Jenny Kleeman
speaker
443 appearances
8 recordings
5 series
first heard Mar 2025
last heard 15 Jul
Jenny Kleeman’s voice in public audio — every appearance, attributed to the second.
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recordings per month · last 12 monthsRecordings per month over the last 12 months — 7 in all, peaking in Jun 2026 with 3.
Appearances
But there are other ways of achieving the same ends.
We can do embryo selection where we screen embryos created in IVF to see which embryos are the carriers of a genetic condition.
and implant only the ones that aren't the carriers of a condition.
Or we can do gene therapy where you deliver a therapy after a person's born.
And the difference between gene therapy and germline gene correction, which is what Cathy wants to do,
When you do gene editing of sperm or of embryos, the changes you make are present in all the cells of the body, including the reproductive cells.
So it means that that person and all that person's descendants will have the changes that you make.
Gene therapies are very expensive.
You have to have a procedure where the medicine is delivered to you.
And sometimes that can be painful and sometimes it can take a long time, but not always.
I wrote a book.
One of the chapters looked at the most expensive medicine in the world, which is a gene therapy for spinal muscular atrophy, or it was at the time that I wrote it.
And spinal muscular atrophy used to be the most common genetic cause of disease for children under two.
So it's quite a common disease.
And I know that SMA, the gene therapy for SMA, which is called Zolgensma, it costs $2 million a dose, but it is delivered within a few hours.
We were having this conversation and Kathy was saying that gene therapy is really bad.
It's really expensive and you have to have chemotherapy.
She was talking about this gene therapy for sickle cell.
And I said, well, not all gene therapies are like this.
For example, Zolgensma, it only takes a few hours to deliver.
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