Kyal Van Der Leest
speaker
124 appearances
1 recordings
1 series
first heard Mar 2025
last heard Mar 2025
Kyal Van Der Leest’s voice in public audio — every appearance, attributed to the second.
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They might follow the extreme thing of, I want to live forever, but then find their happy medium point, sort of like what I did when I started. My extremity came from desperation. I tried everything biohacking on myself before using it on my mum to try and help her with her cancer.
And what worked for me and didn't ruin my health or take from it, I'd have her do, like the hyperbaric oxygen therapy, the red light therapy, all the mitochondrial enhancing and supportive supplements, all the B vitamins, using every type of B vitamin to see which form resonated better with my body, which form worked. Folic acid, no. B6, HCL, no. Those ones ruined me.
But the correct bioidentical forms, I had to learn the hard way. I didn't have to, but I did learn the hard way about you know, naturopathic medicine, nutritional medicine does still have its risks and it does still have potential problems for people if they don't use it appropriately or use it too long. For example, like you can get vitamin A toxicity and all these other things.
Yeah, I definitely am very happy to see the future of medicine is looking a lot more naturopathic. So let's hope the momentum keeps going. And podcasts have been fantastic for that, too. So keep doing what you're doing with your show, Tina.
Oral or injectable, it also depends on the pharmacokinetics. Where do you want the peptide to go? If you have a disc injury in your wrist, for example, or a broken finger, injectable BPC every day of the week versus oral. The challenge with oral peptides is they do need to get into circulation, which... Really, it depends which peptide you're using. Some of them, the chain length is just too long.
Insulin is a perfect example. If they had an insulin pill, there would be no diabetics injecting themselves or in a pump. It's too large of an amino acid to be absorbed orally. So you have to inject it. Unlike ones like KPV, that's an antimicrobial, anti-inflammatory gut peptide. That's three amino acids long. That does not need to be injected.
That can be taken orally, provided it's protected with something like a delayed release capsule. The things that'll break it down are proteolytic enzymes and acid. So the delayed release capsule will get it through the acid.
And things like bicarbonate or sulcoprosate sodium will prevent the acid as well, but also allow it to get through digestion and get distally through the gut where it needs to be to have that effect. A lot of people take our BPC for injuries and they notice it doesn't work immediately. And that's likely because you've got a lot of gut inflammation.
It's working locally exactly where you've administered through capsule.
let the gut inflammation subside or work on your gut health and then try it again and then maybe that 500 micrograms of that peptide that was all being used by your gut actually will get more more of it will get in circulation and then you might break through that plateau that you need to actually start healing that injury in your elbow but be it golfers or tennis elbow or in your foot if you've got a bit of arthritis down there going on or some some issue distally
You need to get over that barrier first of fix the gut health. Like as we said, start all health begins in the gut.
I mean, again, we're not treating conditions here, but autoimmune. community, like if 80% of the gut is hanging around the barrier of your gastrointestinal tract, if you can do anything you can do to reduce gut inflammation, reduces these endotoxins, not mycotoxins, LPS and endotoxins from entering circulation, it calms down your immune system.
The soldiers on the other side of your barrier can chill out finally. They don't have to be hyper vigilant, hyper responsive all the time to this low level of leaky gut or hyper permeability. once they have calmed down, then the whole immune system can calm down.
It can fight off things, other pathogens, other things like dormant viruses, all those other things that people might be dealing with that just kind of get put on the shelf because they're so busy dealing with that gut inflammation. the inflammatory cascade does need to be, that spiral needs to be broken somehow.
And if you have got inflammation, really bad hyperpermeability, that inflammatory cascade is not going to get broken. You can take all the immunosuppressants you want, like you can't do that indefinitely. And when they wear off, it's going to just be ready to go again, unless the gut health is fixed.
Yeah, so that's called Total Recomp, and that's my attempt to create a healthy weight loss, one that supports thyroid function, one that supports stable blood glucose levels, blood sugar, insulin levels. They're called glucose disposal agents, things like Gymnema, which is a naturopathic herb. If you've ever used it, put it on your tongue. It completely numbs your... taste to sweet things.
It's quite an interesting experiment if you've ever got your hands on it to see and taste and all the chemicals and other things that are being hidden behind the sugar. But chromium is another critical cofactor we put in it. Alpha lipoic acid, vitamin B1, all focusing on metabolic health, blood sugar support. But then yet again, harnessing peptides using DNF10, which is a satiety peptide.
It has GLP-1-like effects. It's not comparable. Nothing's comparable to injectable GLP-1s, but it has appetite suppressant effects. It actually acts on peptide YY as well, which is with reduced hunger. So it's not just GLP-1 that the DNF10 peptide works on. So there's two mechanisms for that one.
And then there's a new, not peptide, but people think it is, called SLUPP332 that we included in that formula. And that is basically being called exercise in a pill. It's like an amazing weight loss one that works on the estrogen receptor alpha pathways to help increase fat loss. And it actually has mitochondrial enhancing effect, too. It increases ATP synthesis.
using that with things like fat burners like alkanatine like gbb the precursor to alkanatine albaba which is a mitochondrial uncoupler so that increases your metabolic your um your body temperature it's a thermogenic because instead of pushing through the hydrogen ions in the electron transport chain to atp it uncouples them and sort of creates inefficiency in it but that inefficiency is released as heat so that actually is part of what's called um
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