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Luke O'Neill

👤 Speaker
1510 total appearances

Appearances Over Time

Podcast Appearances

The Pat Kenny Show
Luke O’Neill with some promising advances in treating pancreatic & ovarian cancer

And, of course, what they say is, well, it's the start of it now.

The Pat Kenny Show
Luke O’Neill with some promising advances in treating pancreatic & ovarian cancer

They've got a drug that they can build on, is the idea.

The Pat Kenny Show
Luke O’Neill with some promising advances in treating pancreatic & ovarian cancer

Okay, now, this particular drug, this is not a complicated treatment to get.

The Pat Kenny Show
Luke O’Neill with some promising advances in treating pancreatic & ovarian cancer

It's a pill.

The Pat Kenny Show
Luke O’Neill with some promising advances in treating pancreatic & ovarian cancer

It's not an infusion or anything that intrusive.

The Pat Kenny Show
Luke O’Neill with some promising advances in treating pancreatic & ovarian cancer

That's right.

The Pat Kenny Show
Luke O’Neill with some promising advances in treating pancreatic & ovarian cancer

It's called Daroxin Razib.

The Pat Kenny Show
Luke O’Neill with some promising advances in treating pancreatic & ovarian cancer

Awful name, Daroxin Razib.

The Pat Kenny Show
Luke O’Neill with some promising advances in treating pancreatic & ovarian cancer

Now, it targets, Pat, a thing called Raz...

The Pat Kenny Show
Luke O’Neill with some promising advances in treating pancreatic & ovarian cancer

Now, anybody listening who knows about cancer research would have heard of RAS.

The Pat Kenny Show
Luke O’Neill with some promising advances in treating pancreatic & ovarian cancer

RAS is a gene often mutated in cancer.

The Pat Kenny Show
Luke O’Neill with some promising advances in treating pancreatic & ovarian cancer

So many cancers have RAS mutated, and it's too active, and it causes the cell to divide out of control.

The Pat Kenny Show
Luke O’Neill with some promising advances in treating pancreatic & ovarian cancer

So RAS inhibitors have been around for a while, especially in pancreatic.

The Pat Kenny Show
Luke O’Neill with some promising advances in treating pancreatic & ovarian cancer

This drug really blocks RAS, and that's why they think it's so effective.

The Pat Kenny Show
Luke O’Neill with some promising advances in treating pancreatic & ovarian cancer

And if you knock RAS down...

The Pat Kenny Show
Luke O’Neill with some promising advances in treating pancreatic & ovarian cancer

The cancer stops growing is the idea.

The Pat Kenny Show
Luke O’Neill with some promising advances in treating pancreatic & ovarian cancer

And to see a doubling of survival, that's why it's a headline, I guess.

The Pat Kenny Show
Luke O’Neill with some promising advances in treating pancreatic & ovarian cancer

Nothing before.

The Pat Kenny Show
Luke O’Neill with some promising advances in treating pancreatic & ovarian cancer

It's called unprecedented for pancreatic cancer.

The Pat Kenny Show
Luke O’Neill with some promising advances in treating pancreatic & ovarian cancer

Okay.