Majid Fotuhi, M.D., Ph.D.

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370 appearances 1 recordings 1 series first heard Mar 2026 last heard 1 Mar

Majid Fotuhi, M.D., Ph.D.’s voice in public audio — every appearance, attributed to the second.

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Recordings per month over the last 12 months — 1 in all, peaking in Mar 2026 with 1.

Appearances

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I think that people don't appreciate how important it is to move their body.
Sedentary lifestyle is a major risk factor for cognitive decline, as well as strokes and heart attacks.
Also, recently we have come to appreciate that hearing loss and vision loss can contribute to cognitive decline and dementia.
So I have been talking about how a dozen different medical conditions can contribute to the brain shrinkage that eventually causes cognitive decline and get people to get a diagnosis of Alzheimer's disease.
And so I feel great to know that the international community and this recent paper in Lancet that showed 14 risk factors can reduce the load of dementia in the world by 45%.
But they did not look at all the factors.
It's not just that there are only 14.
There are 14 that they have already studied and established.
There are other factors that, for example, they have not considered and are very important, such as insomnia, if you're sleeping fewer than six hours a night, or sleep apnea, which means you snore at night.
and then you feel tired and groggy during the day.
So the bottom line is that there are many different factors that can contribute to the brain shrinkage with aging, which then causes cognitive decline and Alzheimer's disease.
This is an excellent question, Jason.
So the brain shrinkage that results in cognitive decline and eventually Alzheimer's disease has many components.
One component of it is the amyloid plaques and tau tangles, which almost everybody has heard about these days.
Another component is inflammation in the brain.
Another component is reduced blood flow in the brain.
And another component is the reduced rinsing of the brain that happens mostly at night.
So these are the main components of the super problems, which I describe in my book.
There's a super problems that causes a cognitive decline and brain shrinkage.
Now, the new biomarkers focus on the amyloid plaques and tau tangles.
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