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The a16z Show

Technology Business Science

Episodes

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a16z Podcast: Trends in Cryptocurrencies

19 Dec 2017

Contributed by Lukas

The internet, believe it or not, was just the beginning. Yes, it spawned an incredible number of uses (some unexpected), from marketplaces and commerc...

a16z Podcast: The $200 PC in the Enterprise

19 Dec 2017

Contributed by Lukas

What capabilities do enterprise companies really want from their computers? Twenty years ago, those capabilities might've been bundled into a mainfram...

a16z Podcast: Of Governors and Mayors, and Tech Policy

15 Dec 2017

Contributed by Lukas

Many of the big tech policy issues of the day play out more so at the state and local level, not just federal level. The decisions that cities and sta...

a16z Podcast: Taking the Pulse on Bio

14 Dec 2017

Contributed by Lukas

This conversation between the members of a16z's bio team -- including general partners Jorge Conde and Vijay Pande; Malinka Walaliyadde; and Jeffrey L...

a16z Podcast: Scaling Healthcare

13 Dec 2017

Contributed by Lukas

No matter how grand a vision for a particular industry, disruption in practice is hard. This is especially true in industries like healthcare, which h...

a16z Podcast: Market Shifts

10 Dec 2017

Contributed by Lukas

NASDAQ CEO Adena Friedman runs one of the world's largest financial services companies, including the NASDAQ stock exchange that's home to more than 3...

a16z Podcast: On Data and Data Scientists in the Age of AI

05 Dec 2017

Contributed by Lukas

Data, data, everywhere, nor any drop to drink. Or so would say Coleridge, if he were a big company CEO trying to use A.I. today -- because even when y...

a16z Podcast: AI, from 'Toy' Problems to Practical Application

02 Dec 2017

Contributed by Lukas

When you have “a really hot, frothy space” like AI, even the most basic questions — like what is it good for, how do you make sure your data is ...

a16z Podcast: The Rise of the CCO

18 Nov 2017

Contributed by Lukas

There's a new C-level role in town: the CCO, or Chief Customer Officer. This episode (based on a previous event) is all about the rise of this new rol...

a16z Podcast: How Founders Hire a VP of Product

10 Nov 2017

Contributed by Lukas

Hiring a VP of Product -- especially as the founder of the company -- can almost feel like handing over your baby to someone else to hold, observes a1...

a16z Podcast: Putting AI in Medicine, in Practice

03 Nov 2017

Contributed by Lukas

with Brandon Ballinger (@bballinger), Mintu Turakhia (@leftbundle), Vijay Pande (@vijaypande), and Hanne Tidnam (@omnivorousread) There’s been a lo...

a16z Podcast: The Why Behind the Weird

31 Oct 2017

Contributed by Lukas

Author and professor at George Mason University, Peter Leeson describes himself as not just an economist but as a "collector of curiosa." In...

a16z Podcast: Revenge of the Algorithms (Over Data)... Go! No?

23 Oct 2017

Contributed by Lukas

with Frank Chen, Steven Sinofsky, and Sonal Chokshi There are many reasons why we’re in an “A.I. spring” after multiple “A.I. winters” — b...

a16z Podcast: Platforming the Future

13 Oct 2017

Contributed by Lukas

with Tim O'Reilly and Benedict Evans In this hallway-style podcast conversation, O'Reilly Media founder Tim O'Reilly and a16z partner Benedict Evans d...

a16z Podcast: A New Lab Rises

12 Oct 2017

Contributed by Lukas

with Ion Stoica, Peter Levine, and Sonal Chokshi We’ve already talked quite a bit about the Algorithms, Machines, and People lab at U.C. Berkeley (A...

a16z Podcast: Mindsets for Engineering Biology

06 Oct 2017

Contributed by Lukas

Head of the largest bioengineering lab in the world, former chairman of the FDA and one of the few recipients of the National Medals of Science and ...

a16z Podcast: Why Crypto Tokens Matter

28 Sep 2017

Contributed by Lukas

with Chris Dixon and Fred Ehrsam We’ve already talked about why bitcoin matters. But as the set of cryptocurrencies — and networks and “tokens”...

a16z Podcast: The Case Study of Lyft and Local Governments

26 Sep 2017

Contributed by Lukas

with David Mack, Joseph Okpaku, and Matt Spence How should startups engage with policymakers, build their own government relations (GR) function (whet...

a16z Podcast: Exploding the Map

16 Sep 2017

Contributed by Lukas

with Wei Luo, David Rumsey (@davidrumseymaps), and Hanne Tidnam (@omnivorousread) In this episode, Wei Luo, founding COO of DeepMap -- who build HD ma...

a16z Podcast: Getting Applications Into People's Hands

15 Sep 2017

Contributed by Lukas

with Juan Benet and Chris Dixon The story of how innovation happens is a long one — from government funding early basic research, to the heyday of c...

a16z Podcast: The Asshole Survival Guide

13 Sep 2017

Contributed by Lukas

with Michael Dearing (@mcgd), Bob Sutton (@work_matters), and Hanne Tidnam (@omnivorousread) Bob Sutton's book The No Asshole Rule was all about how ...

a16z Podcast: Adjusting to Trade... and Innovation

10 Sep 2017

Contributed by Lukas

with Russ Roberts, Noah Smith, and Sonal Chokshi Beyond the overly simplistic framing of trade as “good” or “bad” — by politicians, by Econ ...

a16z Podcast: The Macro and Micro of Parenting

05 Sep 2017

Contributed by Lukas

We tend to talk about tech and parenting through devices and artifacts -- screen time, to code or not to code -- but actually, there's a bigger, macro...

a16z Podcast: Competing Against Luck

02 Sep 2017

Contributed by Lukas

with Clayton Christensen, Marc Andreessen, and Steven Levy In business, mistakes of omission may be just as bad as (if not worse than) mistakes of com...

a16z Podcast: Engineering Intent

30 Aug 2017

Contributed by Lukas

"Young hungry and scrappy" is how Hamilton described his country, and it's how many -- including the guests on this episode -- describe star...

a16z Podcast: A Society Under Construction - Modernizing Infrastructure

25 Aug 2017

Contributed by Lukas

What is "infrastructure" actually? In the 19th and 20th century, that usually meant the transportation systems supporting roadways, airports...

a16z Podcast: Cash, Growth, and CEO ❤️ CFO

25 Aug 2017

Contributed by Lukas

with Ben Horowitz, Scott Kupor, and Caroline Moon “The only unforgivable sin in business is to run out of cash” [so said Harold Geneen], yet start...

a16z Podcast: The Taxonomy of Collective Knowledge

15 Aug 2017

Contributed by Lukas

What do disease diagnostics, language learning, and image recognition have in common? All depend on the organization of collective intelligence: data ...

a16z Podcast: Centers of Power, War, and History

11 Aug 2017

Contributed by Lukas

with Graham Allison and Matthew Colford "When a rising power threatens to displace a ruling power, shit happens." It's true of people, it's ...

a16z Podcast: The Strategies and Tactics of Big

07 Aug 2017

Contributed by Lukas

What happens when companies grow exponentially in a short amount of time -- to their organization, their product planning, their behavior towards chan...

a16z Podcast: Independents on the Board

04 Aug 2017

Contributed by Lukas

with Anne Mitchell, Lars Dalgaard, and Scott Kupor"Orthogonal thinking" but "shared core values" -- that's what makes an ideal board... especially whe...

a16z Podcast: From Mind at Play to Making the Information Age

03 Aug 2017

Contributed by Lukas

with Jimmy Soni, Rob Goodman, and Steven Sinofsky Modern technology owes much to the introduction of the binary digit or "bit", first propos...

a16z Podcast: The Curious Case of the OpenTable IPO

24 Jul 2017

Contributed by Lukas

There are the things that you carefully plan when it comes to an IPO -- the who (the bankers, the desired institutional investors); the what (the pric...

a16z Podcast: Making a (Really) Wild Geo-Engineering Idea Real

18 Jul 2017

Contributed by Lukas

Here’s what we know: There’s a pair (father and son) of Russian scientists trying to resurrect (or rather, "rewild") an Ice Age (aka Ple...

a16z Podcast: Addiction vs Popularity in the Age of Virality

15 Jul 2017

Contributed by Lukas

In the age of virality, what does it actually mean to be popular? When does popularity -- or good product design, for that matter -- cross over from d...

a16z Podcast: The Golden Era of Productivity, Retail, and Supply Chains

11 Jul 2017

Contributed by Lukas

This episode of the a16z Podcast takes us on a quick tour through the themes of economics/historian/journalist Marc Levinson's books -- from An Extra...

a16z Podcast: The Cloud Atlas to Real Quantum Computing

30 Jun 2017

Contributed by Lukas

A funny thing happened on the way to quantum computing: Unlike other major shifts in classic computing before it, it begins -- not ends -- with The Cl...

a16z Podcast: Companies, Networks, Crowds

29 Jun 2017

Contributed by Lukas

Is a network -- whether a crowd or blockchain-based entity -- going to replace the firm anytime soon? Not yet, argue Andrew McAfee and Erik Brynjolfss...

a16z Podcast: Lobbying Tech

24 Jun 2017

Contributed by Lukas

What is lobbying, really? Is it “white", "heavy-set" men "playing golf" and making arrangements in "smoke-filled back ...

a16z Podcast: Cybersecurity in the Boardroom vs. the Situation Room

18 Jun 2017

Contributed by Lukas

"We're always fighting the last war" -- that's a phrase historians like to use because policymakers and others tend to be so focused on the ...

a16z Podcast: Taking the ‘Cyber’ Out of Cybersecurity

16 Jun 2017

Contributed by Lukas

Nearly every cybersecurity discussion/presentation follows this formula: We don’t know what we’re doing; the bad guys are getting smarter; our def...

a16z Podcast: Changing the Conversation about Cybersecurity

16 Jun 2017

Contributed by Lukas

When individuals gain the abilities that only nation states once had, how do we put cyber threats in perspective for policymakers -- without unduly &q...

a16z Podcast: Taking the Measure of Tech in Policy -- with Kamala Harris

09 Jun 2017

Contributed by Lukas

"Slow down, cowboys" -- that's what Senator Kamala Harris (D-California) said when prosecutors in her office wanted to bring a case against ...

a16z Podcast: Modernizing Government Services, From Food Stamps to Foster Care

07 Jun 2017

Contributed by Lukas

When people think of modernizing government, they tend to think of new IT, of improved procurement, of new infrastructure ... rather than social servi...

a16z Podcast: The Law (and Tech) of Warfare

04 Jun 2017

Contributed by Lukas

Rules, guidelines, regulations, and “laws” are all sometimes used interchangeably — but what’s legal and what isn’t is far more complex when...

a16z Podcast: The Living Museum

29 May 2017

Contributed by Lukas

Every industry (for-profit, non-profit, government, private-sector) has been touched by tech, with most trying to lead the charge in order to stay ahe...

a16z Podcast: Giving and Getting Feedback -- for Bosses and Employees

26 May 2017

Contributed by Lukas

There's feedback and there's guidance; there's praise and there's criticism. All of it is important to do better work, but to develop a better and mor...

a16z Podcast: What Technology Wants, Needs, Does

23 May 2017

Contributed by Lukas

Turnabout is fair play: That's true in politics, and it's true at Andreessen Horowitz given our internal (and very opinionated!) culture of debate -- ...

a16z Podcast: Tech Policy and the Courts

22 May 2017

Contributed by Lukas

Discussions and headlines around tech policy tend to be dominated by what the President and the White House (aka the executive branch of the governmen...

a16z Podcast: The Blockchain, in Congress

20 May 2017

Contributed by Lukas

There’s an interesting paradox when it comes to the U.S. government and tech: Either they’re an inventor, early adopter, and buyer of emerging new...

a16z Podcast: For Your Ears Only

18 May 2017

Contributed by Lukas

When it comes to spycraft — or rather, “tradecraft,” as they say in the biz — what do the movies get right, and what do they get wrong? In thi...

a16z Podcast: From Jobs to Flying Cars

15 May 2017

Contributed by Lukas

In this lively conversation -- from our recent annual tech and policy summit in Washington, D.C. -- Axios' Dan Primack interviews a16z co-founder Marc...

a16z Podcast: Quantum Computing, Now and Next

13 May 2017

Contributed by Lukas

Moore's Law -- putting more and more transistors on a chip -- accelerated the computing industry by so many orders of magnitude, it has (and continues...

a16z Podcast: Boards, from Both Sides of the Table

11 May 2017

Contributed by Lukas

A board veteran who has sat on both sides of the table, CEO of PagerDuty Jennifer Tejada shares what you gain from board membership (vs. being only an...

a16z Podcast: On Wearables, Quantified Self, and Biohacking

01 May 2017

Contributed by Lukas

It’s the end of the beginning — not the beginning of the end — for wearables, argue the guests in this episode of the a16z Podcast. Especially a...

a16z Podcast: The Rise of the Digital 'Pill'

28 Apr 2017

Contributed by Lukas

The first thing that comes to mind when treating health problems is the need to take a pill (or other pharmaceutical) of some kind. But could a digita...

a16z Podcast: QR. AR. VR.

25 Apr 2017

Contributed by Lukas

In this hallway-style episode of the podcast, a16z partners Connie Chan and Kyle Russell discuss recent announcements at Facebook's annual developer c...

a16z Podcast: The Science Of Extending Life

18 Apr 2017

Contributed by Lukas

Is it real or science fiction to dream of being able to treat… getting old? In this episode, we discuss with Dr. Thomas Rando from Stanford (who dir...

a16z Podcast: Crisis Communications

13 Apr 2017

Contributed by Lukas

A crisis is an opportunity to change one's culture, to model scenarios and set up a crisis plan/process, to become a better company. But it's also a b...

a16z Podcast: Monetizing Open Source (Or, All Enterprise Software)

11 Apr 2017

Contributed by Lukas

Here’s what we know about open source: Developers are the new buyers. Community matters. And there will never be another Red Hat (i.e., a successful...

a16z Podcast: The Changing Culture of Open Source

08 Apr 2017

Contributed by Lukas

The culture of open source has changed across generations, from previous ones that had to fight for the brave new way -- to the current "GitHub g...

a16z Podcast: Cryptocurrencies, App Coins, and Investing in Protocols

03 Apr 2017

Contributed by Lukas

Most of us have probably heard of bitcoin and ethereum -- but did you know there were 15 new cryptocurrencies launched this past month alone? How then...

a16z Podcast: Eyes in the Sky

25 Mar 2017

Contributed by Lukas

In this episode of the a16z Podcast recorded at our inaugural Summit, Jonathan Downey, CEO of Airware, Grant Jordan, CEO of Skysafe, and Kyle Russell,...

a16z Podcast: From Hidden Figure to Sonic BOOM

22 Mar 2017

Contributed by Lukas

An aerospace engineer who worked for NASA for over 40 years, Dr. Christine Darden is one of the mathematicians that the book and movie Hidden Figures ...

a16z Podcast: The Storage Renaissance

21 Mar 2017

Contributed by Lukas

As we enter a new era of distributed computing -- and of big data, in the form of machine and deep learning -- storage becomes (even more) important. ...

a16z Podcast: The Product Edge in Machine Learning Startups

17 Mar 2017

Contributed by Lukas

A lot of machine learning startups initially feel a bit of “impostor syndrome” around competing with big companies, because (the argument goes), t...

a16z Podcast: Build Your Personal Brand

13 Mar 2017

Contributed by Lukas

Your brand, says head of a16z marketing and Outcast Agency co-founder Margit Wennmachers, is what people say about you when you're not in the room. An...

a16z Podcast: The Business of Healthcare

09 Mar 2017

Contributed by Lukas

Starbucks supposedly spends more on healthcare than it does on coffee beans. And 20 years ago, says Rajeev Singh, CEO of Accolade, healthcare was 10% ...

a16z Podcast: The Genetics Of Drug Delivery

07 Mar 2017

Contributed by Lukas

In this episode of the a16z Podcast introduced by Vijay Pande (based on a presentation at our summit event), Russ Altman, Stanford professor of bioeng...

a16z Podcast: Technology, Mobility, and the American Dream

01 Mar 2017

Contributed by Lukas

The irony of our systems working so well -- technological, corporate, and yes, even political -- is that we've become too comfortable: matching to oth...

a16z Podcast: The Future of... You

28 Feb 2017

Contributed by Lukas

Humans have always wanted to enhance themselves -- from getting nutrition just-right to optimizing their performance, whether in sports or health or w...

a16z Podcast: Tech and Entertainment in the 'Era of Mass Customization'

26 Feb 2017

Contributed by Lukas

Imagine, for a moment, an alternative universe: One where Netflix got disrupted by some other streaming-content company that made its DVD rental busin...

a16z Podcast: Brains, Bodies, Minds ... and Techno-Religions

23 Feb 2017

Contributed by Lukas

Evolution and technology have allowed our human species to manipulate the physical environment around us -- reshaping fields into cities, redirecting ...

a16z Podcast: When Will Genomics Live Up to the Hype?

22 Feb 2017

Contributed by Lukas

It's been nearly 15 years since the Human Genome Project was completed. But "are we there yet" in the golden age of genomics? What did we th...

a16z Podcast: Startups, Pivots, Culture, and Timing (Oh Shit!)

19 Feb 2017

Contributed by Lukas

The hardest thing about pivots (major shifts in company/product direction) isn't just the actual pivot. It's the courage to make the decision... and b...

a16z Podcast: Securing Infrastructure and Enterprise Services

14 Feb 2017

Contributed by Lukas

The modern enterprise holds all sorts of applications, devices, and workflow needs. How should we be thinking about securing infrastructure -- and ide...

a16z Podcast: Cars and Cities, the Autonomy Edition

08 Feb 2017

Contributed by Lukas

Thanks to freeways, cities became something to get through instead of something to get to. Now, as the next transportation revolution -- from rivers t...

a16z Podcast: What Startups Should Know about Analyst Relations

01 Feb 2017

Contributed by Lukas

In the age of the internet -- where information is freely available online, and connections between sellers and buyers of software products are visibl...

a16z Podcast: Building Worlds with VR, Art, and Narrative

27 Jan 2017

Contributed by Lukas

Once upon a time, Robert Stromberg got a phone call from "Jim" Cameron (aka James Francis Cameron of Terminator and Titanic fame) about a li...

a16z Podcast: The Why, How, and When of PR

26 Jan 2017

Contributed by Lukas

"Punch above your weight" -- If there's one thing public relations (PR) should help startups and founders do, it's that. Unfortunately, some...

a16z Podcast: VR, AR, and Beyond: The New Medium of Human Experience

24 Jan 2017

Contributed by Lukas

The building blocks for VR and AR are finally here -- but the content is just beginning. So everything you'll actually experience and consume in these...

a16z Podcast: Of Policy, Capital, and the Startup Ecosystem

21 Jan 2017

Contributed by Lukas

How to think about business policy and top-of-mind issues for the tech industry, given a new president? From what agencies matter for startups and VC ...

a16z Podcast: Of Presidents, Policies, and Tech

21 Jan 2017

Contributed by Lukas

How to think about tech policy and top-of-mind issues for the tech industry, given a new president? From what agencies matter for different tech domai...

a16z Podcast: Culture and/of Design

18 Jan 2017

Contributed by Lukas

"Mobile-first" (and now too AI-first) has been a mantra of sorts in design, but what does that mean at a company, product management, and co...

a16z Podcast: Real Estate -- Ownership, Asset, Economy

13 Jan 2017

Contributed by Lukas

The largest asset class in the United States is owner-occupied real estate, yet options for homeowners accessing this are very binary right now: eithe...

a16z Podcast: Machine Intelligence, from University to Industry

11 Jan 2017

Contributed by Lukas

From the significance of Google DeepMind's AlphaGo wins to recent advances in "expert-level artificial intelligence" in playing an imperfect...

a16z Podcast: New Year, New Horizons -- Pluto!

01 Jan 2017

Contributed by Lukas

What (on earth) does it take to get a signal to Pluto? Stanford senior scientist and astronomer Ivan Linscott, part of the team that ran the radio sci...

a16z Podcast: The Movement of Money

31 Dec 2016

Contributed by Lukas

As companies expand out from the internet into the rest of the economy — the proverbial bits to atoms — “the business models are becoming more c...

a16z Podcast: The Realities of Aging / When Healthcare Is Local

27 Dec 2016

Contributed by Lukas

As people live longer, aging is more top of mind than ever. This is especially true for the "sandwich generation" wedged between caring for ...

a16z Podcast: Mobility and the Global Refugee Crisis

16 Dec 2016

Contributed by Lukas

"We throw around words like 'crisis' very easily, but this is a global crisis, and it is of historic proportions," says current U.S. Deputy ...

a16z Podcast: Produce or Perish! (What We Eat)

14 Dec 2016

Contributed by Lukas

Nature is the ultimate complex system, of course — but with today’s technology, it’s now provided us with an “incredible toolkit” of differe...

a16z Podcast: The Internet Is Your Movement

09 Dec 2016

Contributed by Lukas

Clearly disruption plays out not just in business but also in politics. Whether it was the Scottish national party, recent election campaigns, or loca...

a16z Podcast: Health Data -- A Feedback Loop for Humanity

05 Dec 2016

Contributed by Lukas

"We live in a world where we use millions of variables to predict which ad you're going to click on. Whether or not you deserve to get a loan. Wh...

a16z Podcast: Knowledge Builds Technology and Technology Builds Knowledge -- with Joel Mokyr

27 Nov 2016

Contributed by Lukas

The Industrial Revolution (and period between 1500-1700) was an unprecedented age of technology and economic progress — not unlike today’s, in fac...

a16z Podcast: Drones for Delivery in Healthcare

23 Nov 2016

Contributed by Lukas

“If we have instant delivery for our burgers,” says Zipline CEO and co-founder Keller Rinaudo, “we should have it for our medicine.” So while...

a16z Podcast: Old Food, New Tech -- 'Clean Meat'

23 Nov 2016

Contributed by Lukas

You’ve heard the numbers or some statistic like this: By the year 2050, we’ll need to feed 9.7 billion humans on the planet. Our current productio...

a16z Podcast: The Business of Creativity -- Pixar CFO, IPO, and Beyond!

09 Nov 2016

Contributed by Lukas

You've heard a version of this story before: Steve Jobs calls some executive out of the blue to come work for him. Only this time the story turns out ...

a16z Podcast: What's Next for Technology and National Security?

09 Nov 2016

Contributed by Lukas

We live in very interesting times, to say the least -- whether it's a shift in how technology is built and adopted today compared to the past; a chang...

a16z Podcast: Messages and Movements in Politics AND Business

03 Nov 2016

Contributed by Lukas

In business, as in politics, "the movement is the message" -- whether that "movement" is a product that's taking off grassroots-st...

a16z Podcast: So Where Are We on the 'S-curve' for PC Devices?

29 Oct 2016

Contributed by Lukas

There have been a number of new device announcements this past month -- from Google’s new Pixel phone (the first time they made their own phone on t...

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