For our 76th episode, we discuss a recent Journal of Clinical Endocrinology & Metabolism secondary analysis examining pregnancy outcomes among women with polycystic ovary syndrome (PCOS) and gestational diabetes mellitus (GDM). Drawing on data from the DiGest randomized clinical trial, the study explores whether PCOS influences maternal and neonatal outcomes and whether a reduced-calorie dietary intervention benefits women with these coexisting metabolic conditions. Host Chase Hendrickson, MD, MPH, MHCC, from Vanderbilt University, is joined by regular contributor Alison Myers, MD, from Albert Einstein College of Medicine and Montefiore Medical Center, along with guest expert Ellen Seely, MD, from Brigham and Women's Hospital and Harvard Medical School, to discuss "Association between polycystic ovary syndrome and pregnancy outcomes in GDM: A secondary analysis of the DiGest trial" . Together, they examine the challenges of interpreting secondary analyses, the role of PCOS in pregnancy risk, the potential effects of dietary intervention in gestational diabetes, and what these findings mean for the clinical care of women with PCOS and GDM.

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“What did the council decide on item 42?” — answered with the speaker and the moment.

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