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Huberman Lab

Essentials: Therapy, Treating Trauma & Other Life Challenges | Dr. Paul Conti

22 Jan 2026

Transcription

Chapter 1: What is the main topic discussed in this episode?

0.031 - 22.797 Andrew Huberman

Welcome to Huberman Lab Essentials, where we revisit past episodes for the most potent and actionable science-based tools for mental health, physical health, and performance. I'm Andrew Huberman, and I'm a professor of neurobiology and ophthalmology at Stanford School of Medicine. And now for my discussion with Dr. Paul Conte. Paul, thank you so much for being here today.

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23.217 - 30.468 Andrew Huberman

Thank you so much for having me. We could just start off very basic and just get everyone oriented. How should we define trauma?

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30.488 - 53.134 Dr. Paul Conti

I think we have to look at trauma as not anything negative that happens to us, right? But something that overwhelms our coping skills. and then leaves us different as we move forward. So it changes the way that our brains function, right? And then that change is evident in us as we move forward through life. We can see it in mood, anxiety, behavior, sleep, physical health.

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53.434 - 78.782 Dr. Paul Conti

So we can identify it and we can also see it in brain changes. If trauma rises to the level of changing the functioning of our brains, then there's almost always a reflex of guilt and shame around the trauma that can lead us and often leads us to bury it, to avoid it, which is exactly the opposite of what needs to be done. We need to communicate and put words to what's going on inside of us.

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78.862 - 96.803 Dr. Paul Conti

And very often a person knows, but they're not admitting it to themselves because they're afraid of it. They don't know what to do. But if they start talking, then they'll talk about the event or the situation could be something acute or it could be something chronic that really has been harmful to them, right?

Chapter 2: What is trauma and how does it affect us?

96.823 - 119.543 Dr. Paul Conti

And then they feel different afterwards. But that doesn't always happen. Sometimes it's a process of exploration through dialogue, right? Whether it's written or whether it's spoken of the person sort of exploring the changes inside of themselves, maybe changes to their self-talk inside, changes to their thoughts about the world and whether they can navigate safely and readily in it

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119.523 - 139.658 Dr. Paul Conti

And it anchors, as I talk about this, the example I'll use at times is the example of my own life, where when I was much younger, in my early 20s, my younger brother took his life by suicide. And the response of guilt and shame and hiding all of it inside of me

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139.638 - 166.303 Dr. Paul Conti

was was it says very dramatic but but i wasn't acknowledging it right because i didn't know what to do about it and i felt guilty and i felt responsible and i felt ashamed so there was a an avoidance inside of me so so i didn't see that the change was in me but i was taking care of myself poorly like there was enough going on that was unhealthy that i couldn't avoid the realization that like hey i'm different

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166.283 - 173.532 Dr. Paul Conti

now and in these ways that are automatic, you know, my reflex to, can I make my way in the world? Can I have a good life? Can I be happy?

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173.552 - 192.156 Dr. Paul Conti

Well, my reflexes to that were all different and they were coming through the lens of heightened anxiety, heightened vigilance, a sense of guilt, a sense of shame, and a sense of non-belonging in the world and was ultimately good and helpful people around me and my own realization and, hey, things are not going well, right?

192.136 - 199.824 Dr. Paul Conti

that led me to then get some help and to be able to talk about it and realize like, oh my gosh, I need to face these things that are going on inside of me.

200.365 - 223.852 Andrew Huberman

Why do you think that when we experience trauma, these things that we call guilt and shame surface, those emotions must exist in us for some reason. But in this case, it seems like they don't serve us well. So why is it that we seem to be reflexively wired to feel guilty and feel ashamed when that's The exact opposite of what we need to do in the case of trauma.

224.053 - 246.932 Dr. Paul Conti

There's something adaptive that has happened in us through evolution that now becomes maladaptive in the way we live in the modern world, right? So if you think of through most of human development, people weren't living that long, right? And the idea was to survive and reproduce. So traumatic things that happen to us, it would make sense for them to stay with us.

246.912 - 266.608 Dr. Paul Conti

So if you ate a new food and got really, really sick, it's like you better remember that. If you see someone from the group of people a couple of miles away and one of those people attacks you, it's like you better remember that. So the traumatic things that are sort of emblazoned in our brain

Chapter 3: How do guilt and shame relate to trauma?

339.505 - 362.931 Dr. Paul Conti

Imagine a tribe or a group of people that are sheltered together and someone eats half the food at night or something, right? And there's a very negative response, right? And that person feels shame because shame is so powerful to control behavior, right? So the way that trauma can change our brains and stay with us in a way that says be more

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362.911 - 379.215 Dr. Paul Conti

Vigilant, look at the world in a different way, act more defensively, right? And how that links to shame and to guilt. And then guilt becomes what gets called feeling technically, where we relate the aroused affect to ourselves, right?

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379.195 - 395.178 Dr. Paul Conti

So shame, the aroused affect, and guilt, the next step, when the shame gets related to self, are such profound behavioral interventions and deterrents that you can see, I think, how evolutionarily kind of all makes sense.

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395.238 - 411.18 Dr. Paul Conti

If we're fighting for survival and we're an elder statesman, if we make it to 20, this makes sense, but it doesn't make sense in a world where we live much longer, we navigate in all sorts of different ways, And there's so much coming at us that can be traumatizing.

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411.2 - 436.827 Dr. Paul Conti

Our brains are built to change from trauma, but not in the way we experience trauma and not in the way that we live life in terms of the nature of living life and the duration of life in the modern world where these traumas that happen to us are often so bad for us because they change how our brain is functioning and then our entire orientation to the world is different. And that could be for...

436.807 - 461.177 Andrew Huberman

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461.157 - 477.934 Andrew Huberman

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477.914 - 494.427 Andrew Huberman

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494.788 - 514.631 Andrew Huberman

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Chapter 4: What is repetition compulsion in the context of trauma?

558.561 - 568.975 Andrew Huberman

We get to run the experiment again and again in an attempt to solve it. Why is it that somebody who is in an abusive relationship goes on to have a second and third or fourth verbally or physically abusive relationship?

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569.039 - 590.804 Dr. Paul Conti

We see that over and over. It's not necessarily in everyone, but boy, it is in a lot of people who have suffered trauma. On the surface of it, it makes no sense. But then if we think, well, how does our brains actually function, right? We're sort of trained, at least in Western society, I think, to think of ourselves as logical creatures, right?

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591.144 - 609.274 Dr. Paul Conti

That like, oh, we're logical and ultimately everything in us can just boil down to logic. which is completely not true. The limbic system, right? The emotion system, so to speak, inside of us always trumps logic, right? If you think about, does it ever make sense to run into a burning building? I mean, logic says no, right?

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609.615 - 635.631 Dr. Paul Conti

But if someone you love is in the burning building, people run right in, right? Because the limbic system says yes. So when logic and emotion come head to head, emotion wins all the time. And the limbic system does not care about the clock or the calendar. So how I would relate that to the repetition compulsion is when people are repeating, what they're trying to do is to make things right.

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635.611 - 662.26 Dr. Paul Conti

With the idea that if we can repeat the situation and make it right, it will fix everything. Which makes perfect sense if we think, well, where is that concept coming from? It's coming from the emotional part of the brain that wants relief from suffering of the trauma and does not understand the clock or the calendar. So if I can solve something now, I will also solve something in the past.

662.24 - 682.087 Dr. Paul Conti

Which is why I can't tell you how many times I've sat with someone and said, we're starting to do therapy. And a person will say, my last seven relationships have been abusive. And I'll say back something sometimes like, well, look, if you tell me that you've had seven relationships that have been abusive in different ways, I'll agree with you.

682.348 - 703.411 Dr. Paul Conti

I only say that because that's never what someone says, right? But I think what you're going to tell me is you've kind of had the same relationship seven times. So the light bulb that goes off, like I have not had seven different abusive relationships. I have had one that I have repeated seven times. And now we start getting to what's really going on and what needs to happen.

703.451 - 715.264 Dr. Paul Conti

That person needs to face what happened in that original abusive relationship. And it always comes down to the same sort of concepts of the person feeling terrified while the abuse was going on.

Chapter 5: How can one effectively process trauma in therapy?

715.244 - 729.94 Dr. Paul Conti

feeling guilty, feeling ashamed, feeling like, oh, they brought it on themselves, they deserve it, they don't deserve anything better, right? Because the brain is trying to make sense of it, right? Or I thought I could make that okay, but I couldn't, right? And then there's more guilt and more shame.

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730.401 - 750.805 Dr. Paul Conti

And if that's stuck inside of someone, like that's bundled up inside of someone, you know, like a medical abscess inside a person, you know, a walled off infection inside the body, this is the same concept in the brain then of course the limbic system is going to want to fix that. And it fixes it by trying to let's recreate that situation and make it right this time.

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751.306 - 768.268 Dr. Paul Conti

I see that play out clinically over and over again. And why do things get better? Because we go to the trauma and we unlock it. It's not hidden inside where it can control things, right? We bring it to the surface and then we can take away its power.

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768.417 - 789.049 Andrew Huberman

the thought about the thing, the event, or events, plural, evokes this arousal, this internal state, makes some people feel sleepy and exhausted, other people feel really anxious, other people feel angry. I mean, arousal has all these different dimensions, as you know. It's clear we need to confront these things. And so how do we deal with arousal?

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789.129 - 801.748 Andrew Huberman

How does one take what they feel inside about something shameful, What do you do with it in a moment? And does that have to be done in the presence of a skilled trained therapist? How do we deal with that internal arousal?

801.931 - 826.383 Dr. Paul Conti

We so often try and change the trauma of the past in order to control the future. And what that really adds up to is the trauma of the past dominates our present. And then we're not really living in the present, right, as we're trying to control the future. We're not going to do a great job of controlling our future if we're not really living in the present.

826.403 - 845.985 Dr. Paul Conti

And so the way to come at that, again, in the moment, if we're saying, okay, in the moment, if I need to fall asleep, right? I might say, okay, let me try and put that out of my mind. Let me try and thought redirect. So there's short-term strategies that can let us be functional in the context of these changes. But the answer is to go look directly at that thing.

846.586 - 865.755 Dr. Paul Conti

Look at that trauma, explore that trauma. And sure, that can be done with a professional. And sometimes that's what makes sense. But not always, right? Sometimes it can be done by talking to another person, right? Writing it down, right? Looking at what's going on inside of me that my mind is so stuck to this. Let's explore that.

866.015 - 890.433 Dr. Paul Conti

We're so afraid so often of looking at the trauma that has changed us. that we'll look anywhere but at that. What ends up happening is when the person puts words to it, right? It could be in writing, it could be talking to a trusted other or with a therapist, right? Things start to change. I mean, just the fact that you can talk about it, you can put words to it and other people don't recoil.

Chapter 6: What should you look for when finding a therapist?

1008.449 - 1013.816 Andrew Huberman

How do we do that in a way that isn't re-traumatizing ourself in a major way or in a minor way?

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1014.237 - 1034.81 Dr. Paul Conti

It starts with real introspection. When things are bouncing around in our minds, often it's very non-productive, right? It's the same thing over and over again. And that's not helpful for us, right? So if we're just thinking about it and we're thinking in the same way we sort of, in a sense, always think about it, then all we're doing is reinforcing the trauma, right?

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1035.191 - 1057.759 Dr. Paul Conti

But if we can distance enough, then we can think in ways that allow us to have new thoughts. that we weren't having. It's not just bouncing around in our minds. And if we speak or write, there are even more mechanisms that come online in our brains that are then sort of monitoring mechanisms. We think in a different way if we're using words.

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1057.739 - 1075.025 Dr. Paul Conti

are better able often to bring in that observing ego, like what's going on inside of me. So it can be very helpful to think, it can be helpful to talk to someone, to a trusted other, friend, family, clergy, to write. I mean, these are things that can be done without expending any resources.

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1075.445 - 1083.337 Dr. Paul Conti

And sometimes if the symptoms are significant enough, like we really do need to talk to somebody professional who can help us get to the root of the trauma.

1083.818 - 1099.411 Andrew Huberman

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1099.932 - 1114.01 Andrew Huberman

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1114.551 - 1131.486 Andrew Huberman

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1131.466 - 1148.709 Andrew Huberman

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Chapter 7: How do psychedelics assist in overcoming trauma?

1260.708 - 1272.746 Dr. Paul Conti

But I think the person also needs to, you know, take ownership, right, of their own therapy and say, if I don't feel helped enough, well, I have to think about that. and talk to the therapist about that because maybe that therapist isn't a match.

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1272.846 - 1290.662 Dr. Paul Conti

People can get into a rhythm of therapy where it's really not helping them, but they either feel sort of nihilistic about it, like, oh, I'm no better and I'm going to therapy. Do we really need to look at ourselves? And this is where the insurance systems often are very difficult because it's hard sometimes for a person to say, oh, I need more therapy because that may not be possible.

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1290.863 - 1309.064 Dr. Paul Conti

So there are sort of negative factors in the world around us, but ultimately I think the answer to the question comes down to observing ourselves and taking ownership of like what's going on in us and how we're feeling and feeling that commitment to self or to self-care to say, I need to go change this.

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1309.304 - 1320.579 Andrew Huberman

Now I'd like to talk a little bit about chemistry. Yes. Drugs. How do you think about prescription drugs in the context of treating people trauma and other conditions.

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1320.98 - 1341.546 Dr. Paul Conti

And I think that we tend to overutilize medicines in this country because we have a healthcare system that often is so based on throughput that we want to polish the hood when there's a problem in the engine, right? So we overutilize medicines often as an endpoint, right? Oh, we're going to make that person's depression better with an antidepressant.

1341.526 - 1362.218 Dr. Paul Conti

Most of the time, for that person's depression to really get better and stay better, they need to unravel what's driving the depression. So the first kind of branch point can be, what is the diagnosis? What is the level of severity? And I think that's very, very important. And the vast majority of people who are helped by antidepressants, they don't have clinically severe depression.

1363.139 - 1381.967 Dr. Paul Conti

Those medicines create more distress tolerance in us. If you can improve someone's distress tolerance and you can use medicines that take away what clinically is rumination, right? Not the standard meaning of that word, but the clinical meaning of it, where there are distress centers in our brain that are overactive.

1382.347 - 1398.309 Dr. Paul Conti

And then we get stuck in these maladaptive negative pathways where we think about something over and over and over again with no real chance of solving it because that's not what's going on inside of us. So medicines can help that, but we have to have some flexibility around their conception.

1398.489 - 1421.677 Dr. Paul Conti

And the modern medical system of 15 minute visits to a psychiatrist that are weeks apart, I mean, I don't understand how that goes well. We use, I think, approximately five times as much medicine, I think, across the board as, say, the Dutch population. They have a healthcare system and a cultural system that to the best of my understanding is more rooted in taking responsibility for oneself.

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