On Purpose with Jay Shetty

Mark Hyman: Struggling With Brain Fog, Weight Gain, and Low Energy? It’s Likely Hidden Inflammation! (Do THIS to Reverse It)

18 Aug 2025

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Description

Do you struggle to focus on simple tasks? Do you feel mentally “slowed down” during the day? Today, Jay welcomes back his dear friend and trailblazer in functional medicine, Dr. Mark Hyman. Mark Hyman, MD is the co-founder and Chief Medical Officer of Function Health, the fastest growing health company in the U.S. In this extremely vulnerable conversation, Mark recounts his near-death experience after a severe spinal infection left him unable to walk and fighting for his life. Despite decades of living and teaching optimal health, he suddenly found himself dependent on others for even the simplest tasks. Over the course of five determined months, Mark applied the very principles he has championed for years: nutritional excellence, disciplined daily movement, and an unshakable mindset. Not only did he make a full recovery, but came back stronger than ever at the age of 65, proving that the body’s innate healing capacity can be reignited at any stage of life. The conversation explores the critical role mindset plays in recovery and underscores the often-overlooked connection between diet, lifestyle, and overall well-being. Mark explains how chronic illness is frequently driven by hidden inflammation, fueled by ultra-processed foods, sugar, and environmental toxins. He breaks down the science behind his 10-Day Detox, a simple yet powerful reset proven to dramatically reduce symptoms such as fatigue, pain, and digestive distress. The discussion also delves into the growing prevalence of autoimmune conditions, the hidden epidemic of nutrient deficiencies, and why personalized health data is essential for identifying risks before they become life-threatening. In this interview, you'll learn: How to Rebuild Your Health After a Major Setback How to Use Mindset as Your Greatest Healing Tool How to Reduce Inflammation Through Diet How to Spot the Early Signs of Autoimmune Disease How to Use Food as Medicine Every Day How to Take Small Daily Steps Toward Lifelong Wellness Healing isn’t instant, but each intentional choice, a nourishing meal, a mindful moment, a restful night, builds momentum toward changes far greater than expected. With Love and Gratitude, Jay Shetty Join over 750,000 people to receive my most transformative wisdom directly in your inbox every single week with my free newsletter. Subscribe here. What We Discuss: 00:00 Intro 01:33 Overcoming a Life-Threatening Health Crisis 05:39 What is the Key to Healing? 08:15 Breaking Free from Chronic Pain 09:52 The Powerful Tool That Can Reprogram Your Body 15:03 How Inflammation Silently Damages Your Health 18:51 The Hidden Dangers of Sugar Addiction 23:59 Transforming Health Through Functional Medicine 30:34 Why Autoimmune Diseases Are on the Rise 37:04 Signs Your Immune System Needs Help 40:51 Do You Have an Undiagnosed Autoimmune Condition? 42:41 A Simple 10-Day Reset for Your Body 48:06 The Secret to Healing: Treat the Root Cause 52:44 How AI Is Revolutionizing Healthcare 56:32 The Truth About the Chronic Disease Epidemic 57:55 Understanding How Your Body Really Works 59:02 Expanding Access to Quality Healthcare 01:00:56 The Case for Regulating Ultra-Processed Foods Episode Resources: Mark Hyman | Website Mark Hyman | Instagram Mark Hyman | Facebook Mark Hyman | YouTube Mark Hyman | X Mark Hyman | Pinterest Mark Hyman | Books Function HealthSee omnystudio.com/listener for privacy information.

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Mark Hyman: Struggling With Brain Fog, Weight Gain, and Low Energy? It’s Likely Hidden Inflammation! (Do THIS to Reverse It)

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