Precision Cardiology With Cytokinetics

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Vanguards of Healthcare by Bloomberg Intelligence 1h 0m 5 speakers 4 chapters transcribed
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Andrew Galler 0:00
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Andrew Galler 0:42
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Andrew Galler 1:37
Welcome, everyone, to another episode of the Vanguards of Healthcare podcast. I'm your host, Andrew Galler, one of the biopharmaceutical analysts in Bloomberg Intelligence. Bloomberg Intelligence is Bloomberg's corporate research arm, encompassing over 500 analysts worldwide. I'm pleased to be joined today by Robert Blum, President and CEO of Cytokinetics. Robert, thanks for joining us today.
Robert Blum 1:59
Thank you, Andrew. Thanks for the invitation.
Andrew Galler 2:02
So maybe just to kick it off, do you want to give everyone a brief overview of cytokinetics as a company and maybe the 30-year journey you've had from founding to the recent approval of your first FDA-approved drug, mycorrhizal?
Robert Blum 2:14
Very pleased to do that. And ours is somewhat of an uncommon story. And to your point, it goes back some time, not quite 30 years, but certainly a long time. This is our 28th year. since we began operations as a company. And I was privileged to launch this company alongside of scientific founders and other scientists who were experts in an area of biology that we committed to mine for a new pharmacology. And we like to joke nobody's ever going to accuse us of being an overnight success. But we have been working very diligently and with focus to build an unusual type of company, one very disciplined to this biology, and that is the cytoskeleton and the mechanics of cell behavior, and a business that's rooted in a different approach to how we
Robert Blum 3:19
aim our science, where we access and how we deploy capital, and how the R&D and commercial ambitions of the company synchronize to align to where we are today. Cytokinetics has pioneered and leads in this area of muscle biology, specifically towards a pipeline of new medicines in specialty cardiology, And that culminated in an FDA approval of our first medicine in December, coincident with approval in China, and also a positive CHMP opinion all in December. And as was enabling of us to turn the page onto our business, as we now go to market, a REMS program and enabling of physicians to be certified for patients to be getting our first medicine, a drug called mycorzo that's now approved for the treatment of obstructive HCM in the United States.
Andrew Galler 4:39
Absolutely. And maybe before you get into the nitty gritty of that launch and your product profiles and everything else, maybe just a high level of philosophical question on cardiology in general. Because like over maybe the last 20 to 25 years, it's definitely shifted to more of a specialty and precision driven field of medicine. Whereas before that, it was kind of a one size fits all approach where someone would go in with cardiac issues, they would get ASR, beta blockers, diuretics, and so on and so forth. Do you agree with that statement?

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