paroxanthine
product
5 mentions
2 recordings
first heard Mar 2026
last heard 9 Apr
±0 this month
Paroxanthine, a primary metabolite of caffeine, acts as an adenosine receptor antagonist and influences stimulant effects.
Trend
No mentions in the last 30d.Widen the range to see when paroxanthine was said.
Moments
newest first · ▶ plays the momentUnknownLessWrong (Curated & Popular) · "The effects of caffeine consumption do not decay with a ~5 ... · 1:46 · 9 Apr
…Since paroxanthine is by far the dominant primary metabolite, and its further metabolites are mostly either very short-lived or have poor affinity for adenosine receptors, we can fruitfully use a simplified model of caffeine-paroxanthine elimination.…
UnknownLessWrong (Curated & Popular) · "The effects of caffeine consumption do not decay with a ~5 ... · 1:39 · 9 Apr
…Paroxanthine then has its own 3-5 hour half-life as it's metabolized into a handful of other things.…
UnknownLessWrong (Curated & Popular) · "The effects of caffeine consumption do not decay with a ~5 ... · 1:29 · 9 Apr
…In particular, more than 80% of circulating caffeine is metabolized into paroxanthine, which has a comparable binding affinity at adenosine receptors to caffeine itself.…
5 moments · sign in to read them all