Dave Asprey

speaker

17,208 appearances 48 recordings 1 series first heard May 2026 last heard 14 Aug

Dave Asprey’s voice in public audio — every appearance, attributed to the second.

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recordings per month · last 12 months

Recordings per month over the last 12 months — 48 in all, peaking in Jul 2026 with 18.

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The Human Upgrade: Biohacking for Longevity & Performance · Dave Solo Pod: The Original Smart Drug Masterclass : 1518 · 13 Aug 2026 podcast

Belgium was looking at GABA-related molecules.

And he was trying to find a new sedative for the drug industry.

And as you may recall if you listen to my videos, GABA is a common amino acid that's also a neurotransmitter.

You want more of it to chill, more of it for sleep, and more of it if you're stressed.

Problem is.

Paracetam didn't behave right because it affects learning and brain function, but it doesn't sedate or stimulate.

And

The scientist, after a lot of examination, said we need a new name for this category of drug.

And he coined the term nootropic, which we all use today.

And it means mind plus bending or shaping.

So this is a mind-bending or mind-shaping pharmaceutical.

And here's the original list of what makes something a nootropic.

It needs to enhance either learning or memory, it should increase your brain's resistance to.

Disruption, it should protect your brain from some types of injury or chemical stressors, it should improve higher order control, and it should have low toxicity or other psychoactive effects.

So if LSD did all this stuff, but you were tripping balls all day, well, that might not be aneutrophic, but microdosing it could be.

Now that definition.

I like it.

But it's way stricter than the way marketing companies will throw the word nootropic around.

Reddit often calls caffeine stacks and adderall nootropics.

Gorgea meant something that made your brain function better and protected it.

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