Dave Asprey
speaker
17,208 appearances
48 recordings
1 series
first heard May 2026
last heard 14 Aug
Dave Asprey’s voice in public audio — every appearance, attributed to the second.
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recordings per month · last 12 monthsRecordings per month over the last 12 months — 48 in all, peaking in Jul 2026 with 18.
Appearances
So I do not believe that caffeine or certainly amphetamines are nootropics.
They're just stimulants, and nootropics are not stimulants by definition, but you may benefit.
From stimulants as well.
Now, the original brassetams weren't built for you to study, although they sure worked for that for me.
They were built for neurological use and clinical use, which is why the first ones launched back in the 70s were made by Big Pharma.
And the Silicon Valley smart drug identity arrived later, largely in part to my friend and mentor, Steve Folkes, who was one of the big voices and wrote the smart drug news.
Through all the 80s and 90s, and taught me a lot about this stuff, which is why I can share with you today.
Thank you, Steve.
And yes, Steve's been on the show.
So, what is a rastetam?
It's a synthetic compound that has a pyrolodone ring, which is a chemical signature of all rastetams.
They're cyclical derivatives of GABA.
So they're related structurally to GABA, but they don't actually hit the GABA receptors.
So chemically related.
But functionally unrelated.
And that's why they were such weird drugs, and why even today we don't quite know all of the reasons they do what they do.
And it benefits or and it helps that they're small molecules that go into the brain easily.
One of my favorite tweaks to the original paracetam was adding a fat-soluble group, which makes it into anoracetam, which is the only one that increases memory I.O.
That's the
The one that I take almost every single day and sometimes others.
Showing 241–260 of 17,208 · page 13 of 861
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