Dave Asprey
speaker
17,208 appearances
48 recordings
1 series
first heard May 2026
last heard 14 Aug
Dave Asprey’s voice in public audio — every appearance, attributed to the second.
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recordings per month · last 12 monthsRecordings per month over the last 12 months — 48 in all, peaking in Jul 2026 with 18.
Appearances
The ampiest of them is when you add a phenol group called phenol paracetam, which goes into the blood-brain barrier faster, and you feel like you're on a stimulant, because it really does uh act that way.
The racetam backbone also shows up in some anticonvulsants, like levitaracetam and brevaracetam.
It's the same ring, totally different mechanism.
Those aren't things you would take.
for studying, but there are some very interesting derivatives of the racetams that we're using in the nootropic community.
So here's the difference between a nootropic racetam and a conventional stimulant.
Stimulants, huge shifts in dopamine and norepinephrine and global arousal in the brain.
Racetams, they have a very weak affinity for the receptors that you would normally hit with sedatives or stimulants or opioids or benzos.
And racetams work because they change the efficiency of signals you already have.
They don't just pound on the receptor the way that some of these more powerful psychiatric drugs do.
Or you can think of it like this a stimulant is stepping harder on the gas in your car.
But a
The RAS attempt tunes the engine and the wiring so that there's just less friction and the car goes faster.
So think of it like a tuning fork.
And that's why subjectively I missed the effects the first time I took it, because they were subtle.
And if you're super healthy, you may not really notice it, even though you're getting neuroprotection from it.
Next, let's get into how RAS attemps work.
What are the mechanisms?
And I won't get too nerdy on you here, but
But I am going to talk about neurotransmitters because many people at this point have heard of things like acetylcholine and dopamine or GABA.
Showing 261–280 of 17,208 · page 14 of 861
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