Dave Asprey
speaker
17,208 appearances
48 recordings
1 series
first heard May 2026
last heard 14 Aug
Dave Asprey’s voice in public audio — every appearance, attributed to the second.
Trend
recordings per month · last 12 monthsRecordings per month over the last 12 months — 48 in all, peaking in Jul 2026 with 18.
Appearances
Now, the next thing the RASTMs do is they change your glutamate and AMPA signaling.
Now, I'll tell you what that means.
Glutamate is really important.
It's the main go signal in your brain.
In fact, if you've ever heard of monosodium glutamate, that turns the go signal on so fast that people get migraines from it.
But you need glutamate working in the brain.
The brain, or your brain just won't go.
And the amporeceptors are think of it, the things that catch the signal.
So if you get a clean handoff of glutamate, the amporeceptors are going to be happier.
And what anoracetam and the other drugs like it do is they keep those AMPOReceptors responsive longer so that they can take better advantage of energy in the brain.
Or you can think of it like this: glutamate's a key and the AMPORceptors a
door and Rasetem oils the hinges and the lock so the key just slides right in.
And learning happens when neurons strengthen connections.
So, if you have a better handoff of glutamate to AMPA, you get more plasticity and you can learn better.
Very, very different from root stimulation.
And you can think of stimulating everything in your brain as adding random noise.
And what you want to do is turn up the music, not the sound of the crowd.
That's what we're doing here.
Now it gets really interesting when we look at the next mechanism of these nootropics.
And it has to do with membranes and mitochondria.
Showing 321–340 of 17,208 · page 17 of 861
← Previous
Next →