Dr. Chantelle Thomas
speaker
1,116 appearances
2 recordings
1 series
first heard Jul 2026
last heard 30 Jul
Dr. Chantelle Thomas’s voice in public audio — every appearance, attributed to the second.
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recordings per month · last 12 monthsRecordings per month over the last 12 months — 2 in all, peaking in Jul 2026 with 2.
Appearances
I'm not sure if you're familiar, but one of the reasons why people might talk about wanting to stop a psychotropic for anxiety or depression is they say, okay, the lows are not.
so low, but the highs have also been truncated.
So everything kind of comes into this more manageable range.
Whereas I would say most people would describe the subjective experience of a psychedelic actually expanding the range of what they can feel.
And so that's also just an interesting thing to think about in terms of what's happening on a at a neurochemical level.
Um, and what's the underpinning in terms of the idea of like how do we feel about our own experience or the access we have to our own experience, which I think some people could reasonably argue gets wider and larger with subjective effects of different compounds.
Interesting.
So um ketamine therapy in an I in an infusion clinic, for example, is looking at just creating conditions to expose the brain to this compound and hoping that the neurochemical effects will optimize someone's window for experiencing depressive symptom relief just based on the signature of the medicine.
Most of those places are not looking at the interaction effect with someone's unique history or the way they experience the ketamine as having an impact on the outcome of the ketamine.
That's not to say that they're not paying attention to, you know, the environment to some extent.
Whereas, um, but they're not, they don't put a lot of stock in the subjective experience of ketamine itself.
Maybe the only place where they're concerned about it is if someone is starting to have a really bad experience with ketamine, then they would turn the amount of ketamine that someone's receiving down and in some instances even administer a benzodiazepine on top of that, which would be a little more rare to help them manage whatever they're encountering with if it's difficult or challenging.
Whereas ketamine assisted psychotherapy is the idea that you use the subjective effects of ketamine itself, in addition to all the biological effects and the neurochemical effects which are beneficial.
And you use those subjective effects as a window into someone's consciousness and what matters and what they're experiencing and the felt sense of what happens is yields highly therapeutically valuable content.
It's not just about what happens during that session, but it's also how you integrate that information over time that suggests whether or not those effects are going to be more durable.
There's a durability issue with ketamine, which infusion.
clinics have addressed and but what I mean by durability is how long it lasts and for how, you know, what's the length of time that someone might get relief from their depression if they're going to respond.
And for
There are people that don't respond.
Um conservative estimates around some of the research shows sixty to eighty percent response rate, which seems quite high.
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