Dr. Craig Koniver

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302 appearances 1 recordings 1 series first heard Oct 2024 last heard Oct 2024

Dr. Craig Koniver’s voice in public audio — every appearance, attributed to the second.

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I have not seen that.
That can be compounded. What's the dosage on hexarone that you typically prescribe? 100 micrograms. It's the same as these other like ipramoron GHRP6, 100 micrograms. The two that are different would be tesamoron. Ideal dose is 2 milligrams per dose, which is 2,000 micrograms, so quite different. And then semoron has actually a very broad dosing range, anywhere from 200 micrograms.
I've used it up to 3,000 micrograms, depending on your goals.
Yeah. And I think people are familiar with it. You know, some people are talking on podcasts about the MTHFR SNP. We've not talked about that on this podcast. So it'd be nice. Sure. So a SNP is a single nucleotide polymorphism, meaning that genetically things don't flow as easily. Again, that's an oversimplification.
And, you know, you could be homozygous for that, meaning you have both genes making you, you know, influencing you more. You could be heterozygous, meaning it's just one gene. One copy from one parent. Yeah. Or homozygous copy from each parent. Yeah, you said it way better than I did. And so what that means is, and where we see that reflected, homocysteine is a marker we use, a lab marker we use.
It's an emerging marker for looking at one's cardiovascular risk profile. And so if one's got an elevated homocysteine, and elevated by some labs can be greater than seven, by most labs greater than nine, means you're at an increased risk. What that is, I don't remember, but you're at an increased risk of having a cardiovascular event, which would mean a heart attack or stroke.
And so we want to lower that number. And the best way to lower that number is taking ample methylated B vitamins. Methylated means you're adding a methyl group. So methyl B12, methylfolate, trimethylglycine, methionine. These are all methylation donors. which just metabolically and through your detoxification pathways in your liver is going to help you lower that homocysteine.
I'm sure it's more complicated than that, but that's most people. If you're going to take a B vitamin, take a methylated B vitamin because then you overcome. Again, we've done a lot of MTHFR testing. I don't think it's as profound as some people make it out to be like it's going to change their life. I've never seen that. Can it help you?
Sure, but you're going to overcome it by taking sufficient methylated B vitamins anyway.
B12, folate. There's a methylated B6. And then trimethylglycine. TMG is a good compound. Methionine is a good methyl donor. It's an amino acid. Are these taken in the morning or in the afternoon? I like taking them in the morning, although... I think, you know, for people to play around with, because I've certainly seen it, you know, people get that 3 p.m.
kind of slumber as opposed to reaching for the coffee or the donut. Take some more methylated B vitamins and see what happens. Or just the coffee. No, sorry.
That's exactly it. You've nailed it. Yeah. I remember when you messaged me after starting it and you were like, This is amazing. It's amazing. Yeah, you were saying it's amazing.
I hope so too. No, but I mean, your response is what we see with our other patients who are loving. And I think that combination with glycine, I'm a big fan of glycine and injecting it seems to work really well. But back to your question about Penelon, Yeah, I mean, it's one of the smallest peptides, but I think it's one of the most profound.
We used to combine it with epitalin, the Russian peptide that was used for circadian rhythm.
Yeah. Again, put on the do not compound list with all the others. That's a shame. That's gone. But Penelon stays and remains. And yeah, your response to it and experience with it has been very commonplace from working with patients and seeing that. I think there's a sort of circadian rhythm aspect with it as well, you know, and helping with melatonin production.
Obviously, that comes from the Penel gland. This is just, I'm postulating. I think there's more to the pineal gland than we understand.
Yeah, and I think it's kind of elusive, but I think there's something to it. And I say that having used a lot of pineal gland with people over the years and having very similar responses, which is awesome. Like, everyone knows, like you said, when you sleep better, your entire day is better. When you sleep better, your life is better. Like, exponentially better.
Yeah.
Yeah. Wild. Yeah. And it's, I mean, I think it's worth noting that you, you also take care of your health on many other aspects and that's probably why you were sensitive to it, but it worked really well for you. Right. And some other people, it's going to take longer, you know, if they're
you know, having to work on their diet and having to work on their exercise and having to work on their thought patterns. We don't talk about that enough, having positive thoughts. But yeah, it's been, it's so safe. We've never, ever seen, I mean, I never, ever have seen a side effect or negative side effect from Penelon. It's, and, and your response has been uniform.
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