Dr. David Perlmutter
speaker
551 appearances
1 recordings
1 series
first heard Jul 2026
last heard 9 Jul
Dr. David Perlmutter’s voice in public audio — every appearance, attributed to the second.
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recordings per month · last 12 monthsRecordings per month over the last 12 months — 1 in all, peaking in Jul 2026 with 1.
Appearances
So that
That's what happens once there's a stimulation of the M2 microglia, like from we mentioned earlier from inflammatory chemicals, from being uh diabetic, from being overweight, from being uh having uh hypertension, all of these things conspire to shift the microglia.
Once they do, the mitochondria shift to glycolysis.
So you're putting out much less ATP.
Right.
Right.
And here's the corollary that I think is really interesting.
You can have a healthy M2 microglial cell.
If you threaten its mitochondria, then it will shift.
So it can go either way.
Oh wow.
Whatever shifts the M2 to being destructive will damage the mitochondria.
And if you damage the mitochondria directly, it'll shift them to being destructive as well.
As an example, MPTP was a contaminant.
in IV drugs that were some people in the early nineteen eighties were using, and they developed Parkinson's within one day.
Right.
And thirteen years later, when one of them died, Dr.
J.
William Langston, who was the one who first discovered this,
looked at the brain and what did he see?
Showing 241–260 of 551 · page 13 of 28
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