Dr. Mike Roberts

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1,217 appearances 1 recordings 1 series first heard Jul 2026 last heard 8 Jul

Dr. Mike Roberts’s voice in public audio — every appearance, attributed to the second.

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Perform with Dr. Andy Galpin · What Drives Muscle Growth & What Doesn't | Dr. Mike Roberts · 8 Jul 2026 podcast

What you're seeing in terms of hypertrophy is mainly radial hypertrophy, which is saying that the cross-sectional area of the tissue is increasing in size.

How do you measure that, right?

So you can do muscle imaging.

We do ultrasound in the laboratory.

We have a panoramic so we can actually look at the rectus femoris, the vastus lateralis, and we can see something to the tune of, we'll call it 15% increases in the cross-sectional area of that muscle tissue.

And then from there, we can take muscle biopsies.

That's mainly from the vasus lateralis.

Our lab does the vasus.

And we'll see probably, I would call it 20% to 25% type 2 fiber cross-sectional area increases.

So at the cellular level, those type 2 fibers, fast twitch fibers, are increasing 20%, 25%.

uh and it's preferential for type two because type one sometimes depending upon training status we won't see any hypertrophy or in the untrained individuals we'll see something like a 10 increase in cross-sectional area interesting so you say okay the tissue is increasing in cross-sectional area the cells are increasing in cross-sectional area what's going on inside of those mild fibers or muscle cells

Until recently, we frankly didn't know.

And you had mentioned some of our research gets sort of misquoted a lot of times or misapplied.

There are different modes of hypertrophy that we think exist.

The conventional realm of hypertrophy would be that as your fibers, your muscle cells, as they increase in size, you are having a proportional increase in myofibrillar protein content, which are your contractile proteins.

They allow the muscle to function, right?

And then the question became, all right, well, is it the preexisting myofibrils within those myofibers that increase in size, or do you have an increase in the number of myofibrils?

And luckily, we were able to work with a very smart guy, professor at Wisconsin, Troy Hornberger,

He had a fluorescent microscope technique where he did a really neat sort of resistance training model in his mice.

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