Jeff Krasno
speaker
350 appearances
2 recordings
2 series
first heard Jan 2025
last heard Mar 2025
Jeff Krasno’s voice in public audio — every appearance, attributed to the second.
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Appearances
But then my mitochondria would look around and say, I need an energy substrate in order to make heat to get Jeff back up to 98.6. but there's not a lot of glucose around. So what are my options? Fat, oxidized fat, convert triglycerides into free fatty acids to use in my brown fat, particularly to upregulate my body temperature. And I started to just burn fat like crazy.
And, you know, as I started to stack those protocols together, just purely for weight loss, I lost really 40 pounds in a couple of months. So I know that cold water therapy has pros and cons for different people. I know some people absolutely abhor it. Count me in that group, even though I do it every day.
I mean, I was one of these people that would go into like paroxysms of anxiety, just like looking at a cold lake, you know, whatever. But over time I acclimated myself to that practice, um, There's all these other benefits to it, psychological benefits that I think are quite astonishing. There's also mood regulation. There's a secretion and production of a lot of dopamine, et cetera.
But I found that for me, this was a very, very highly effective protocol.
Right. Well, again, because I started to understand the underlying mechanism of what was happening. I mean, I could measure my blood glucose at 10 a.m. It was low, you know, 70s, maybe 80s. And so I'm just trying to put one and one together and just report on my own. I get it. I think that we should do those studies.
Yeah. Sid Mukherjee, who wrote The Emperor of All Maladies. And if anyone wants to read a book about cancer, which is not always the most uplifting topic. It is one of the most beautifully written books ever really on any topic. But yeah, this, this idea of the Warburg effect with, with cancer.
So, you know, which is like, like essentially a dysfunction around glycolysis, anaerobic respiration that leads to the proliferation of these malignant cells and a lot of metastasis. If you can quote unquote sort of starve that of glucose, there could be something there. So I think it's like doing some of these studies that combine the,
you know, fasting techniques with chemo or fasting with other forms of immunotherapies. You know, I think these are fascinating and much needed. Have you ever interviewed Thomas Seyfried?
Okay. I got to listen to that.
I mean, these are very important anecdotes because sometimes it is these outliers that then lead to more clinical study, right? So like, for example, Jimmy Carter, I believe, had like brain cancer, some sort of glioblastoma. He had this immunotherapy, which...
I believe was with the application of like a Keytruda, but then in combination with a particular probiotic, I believe this was true for Jimmy Carter, but it is definitely true now for treating some forms of cancer that immunotherapy plus like acromantia, which is a particular strain of bacteria, a beneficial strain, actually yields better results.
And so now I think they're starting to do more studies about combining immunotherapies with the right kinds of probiotics, et cetera. So this is like, you know, this is the new frontier. This is actually where AI can become very, very interesting too.
That's not my, obviously my field of expertise, but I think when you start to be able to, you know, use these large models to crunch that kind of data, this is, I think more, one of the most exciting sort of precipices of where we are.
Yeah, I mean, I'm generally an optimistic human being, so I'm trying to leverage that part of me. I'm worried more about, I think, general epistemology and sort of the erosion of reason and rationality and the ability to have kind of nuanced, thoughtful conversations. We live in this attention or persuasion economy, I guess you might call it, where essentially we've taken Drew's time and focus.
I mean, everybody's time and focus and we've productized it and commodified it and we buy it and sell it. And for better or worse, you know, we all exist on social media or we, we all consume a lot of 24 hour news, whether many of us try to avoid it, but that is essentially algorithmically preferenced for salaciousness and scandal and hyperbole, et cetera.
And so we have these agitated nervous systems as part of this bigger kind of non-consensual system. psychological experiment of this attention economy. And that really does worry me because it tends to amplify the least rigorous voices and the voices that tend to not really value nuance or common ground or really any effort at sort of finding the middle.
So that is a concern of mine, because I think what we've seen is erosion and just basic epistemology. Certainly, we've seen a lot of erosion in trust of the institutions of liberal democracy that have long kept us semi-stable. And in many cases, those institutions have done a lot of insult and embarrassment to themselves.
I mean, I'm talking about, you know, media, government, institutions of higher learning, certainly food system, pharma, et cetera, you know, A lot of these institutions have really done a lot to undermine public trust in them.
And yet at the same time, there is so many sort of misaligned incentives or perverse incentives to continue to sort of burn down these institutions instead of actually making them better. And this does concern me because I don't really know what's on the other side of liberal democracy.
You know, I don't hear a lot of really thoughtful, cogent alternatives to it, you know, outside of, you know, tyranny and despotism and kleptocracy, et cetera, which I feel we're sort of like on the quasi verge of at this very moment. So Yeah. That's a complicated answer.
Showing 81–100 of 350 · page 5 of 18
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