Mike Israetel
speaker
1,094 appearances
5 recordings
5 series
first heard Dec 2024
last heard May 2025
Mike Israetel’s voice in public audio — every appearance, attributed to the second.
Trend
recordings per month · last 12 monthsNo recordings in the last 12 months.Older appearances are listed below; set an alert to hear about the next one.
Appearances
It can be 250 primo and anything between. And you kind of experiment that in a lot of bodybuilding coaches.
What they're really good at is starting you on a certain cycle that they have the wisdom to know works for most people, and then leveling up one drug, leveling down another to get, among other things, kind of that testosterone, that androgen to estrogen ratio to be something that you have your best performance at, best health, so on and so forth.
But the sex drive component, especially if you have a lot of estrogen going on, qualitatively it can change, quantitatively it can change. Now, huge variation. Me personally, I never got like enormous sex drive upregulation. I did get some, but nothing crazy. I've been up to as much as just north of 2000 milligrams per week.
Currently, I'm only 250 milligrams per week, but my sex drive is more or less the same.
There are some reasons to believe that your androgen receptor density escalates up when exposed to more androgens and not down in some cases. And so that means the more gear you take, the more benefit you have, rather linearly. My experience, the experience of most people you talk to, it's, again, slow newsreel, same asymptotic curvilinear relationship.
For me personally, and this is something I didn't discover until quite recently, I would say, unfortunately so, I get probably almost the same gains at 1000 milligrams that I do at 2000. Anything north for me of 1500 just drives me insane, mentally insane, and seems to not really affect my physique hardly at all. How much water retention do you get at these doses?
Considerable, although if you manage your estrogen well, it's not as much as you would think. Managing estrogen with aromatase inhibitors? Oh, yes, that's right. Sorry, I had a point there back then. Aromatase inhibitors in many cases are incredibly toxic drugs. And you generally want to avoid taking them if you can.
Sometimes you have to to get really dry for a contest, but that's only a few weeks out from the show.
And so the modern wisdom, so to speak, with the evidence-based crowd, the safer use crowd, is to manage your estrogen with differential amounts of testosterone and non-estrogenically converting compounds like primobol and mastron versus taking just as much testosterone as you ever would, but taking an aromatase inhibitor on top of that.
Because aromatase inhibitors, in an unbelievable range of circumstances, fuck you up. They're neurotoxic. They're cardiovascularly toxic. It's bad, bad news. These are the compounds you use when you have breast cancer. And they're like, you're going to die if you don't take these. They are gigantic hammers for a very small nail.
If you want to see who's done the worst to their health across the bodybuilding industry, it's whoever runs the most AIs, as we call them, aromatase inhibitors. And there are various other pharmaceutical ways to control estrogen.
Probably the best way for health and effect is only use as much estrogenically converting drugs, nandrolone derivatives, and testosterone as you need to get whatever estrogen you feel best at. And the rest of the... Anabolic load should come from things like primobolin and mastron that don't really do much to your estrogen at all, but increase your androgen and anabolism, so on and so forth.
Nandrolone has some really cool positive effects, kind of exaggerated versions of testosterone. Some people are naturally very dry. And so if they don't take a Nandrolone for their very hard training cycles, they will have insufficient body and joint water, hydration. Joints will creak and they'll get hurt a lot and it's just really bad recovery.
But you put them on Nandrolone variant and all of a sudden they have enough intramuscular and intra-joint water to where they feel great, everything's working. Other people will get on nandrolones and have so many of the side effects that they're like, well, this is way too much estrogen conversion for me. I'm a giant water buffalo.
If I just take testosterone, I'm plenty hydrated, so I don't need to do that. Nandrolones also have this curious side effect. It's colloquially termed DECA-DIC. Nandrolone decanoate is a substance called DECA. It is erectile dysfunction, approximately caused by the presence of nandrolones. And it's curious because nandrolones typically with their estrogenic effects elevate sex drive.
Kind of the more estrogen you have to a point, the more sex drive you have. If you have presence of androgen. If you have presence of testosterone. And so you're horny. But little Billy down there doesn't work as well as he used to or at all. And so if you're in that boat, you're like, well, look, it's just trade-off.
How much of a benefit do I get in training versus how much is my wife or girlfriend going to hate me or hookup culture doesn't work for me anymore, so on and so forth. So lots of considerations there. Nothing generally better than to start out with a solid plan that makes sense with a coach that knows what they're doing at very low doses of everything.
And slowly play with compounds and scale up the very notable, highly note your beneficial effects and highly note your deleterious effects or downsides and see where you can strike a balance that's acceptable to you and considers long-term consequences, et cetera, et cetera, et cetera.
40.
When I was 27 years old.
Showing 581–600 of 1,094 · page 30 of 55
← Previous
Next →