Nick Norwitz

So more than double the effect of the statin by eating Oreos.

Me understanding the physiology in myself. So we talked about different things can drive biomarkers up or down, and the context matters. So our understanding of why lean people have high LDL and low carb has to do with the fact that the leaner and the more insulin sensitive you are,

Me understanding the physiology in myself. So we talked about different things can drive biomarkers up or down, and the context matters. So our understanding of why lean people have high LDL and low carb has to do with the fact that the leaner and the more insulin sensitive you are,

Me understanding the physiology in myself. So we talked about different things can drive biomarkers up or down, and the context matters. So our understanding of why lean people have high LDL and low carb has to do with the fact that the leaner and the more insulin sensitive you are,

when you go low carb when you go keto and the carbohydrate stores and your liver starts to drop it kicks off this cycle whereby you're burning a lot more fat as fuel and you're actually releasing more free fatty acid from your fat cells into your bloodstream and then those free fatty acids need to cycle throughout the the liver and then back through the body so they get taken up by the liver packaged on these big ship-like particles containing cholesterol and stored fat

when you go low carb when you go keto and the carbohydrate stores and your liver starts to drop it kicks off this cycle whereby you're burning a lot more fat as fuel and you're actually releasing more free fatty acid from your fat cells into your bloodstream and then those free fatty acids need to cycle throughout the the liver and then back through the body so they get taken up by the liver packaged on these big ship-like particles containing cholesterol and stored fat

when you go low carb when you go keto and the carbohydrate stores and your liver starts to drop it kicks off this cycle whereby you're burning a lot more fat as fuel and you're actually releasing more free fatty acid from your fat cells into your bloodstream and then those free fatty acids need to cycle throughout the the liver and then back through the body so they get taken up by the liver packaged on these big ship-like particles containing cholesterol and stored fat

They're called VLDL. And then the VLDL dropped the stored fat, the triglycerides, back off at the muscle tissue and the fat tissue. And what happens in this process is that those big particles that are packed with the stored fat have the fat siphoned out of them. They shrink down into LDL particles that contain LDL cholesterol. And what you end up with as a result of this system is very high LDL.

They're called VLDL. And then the VLDL dropped the stored fat, the triglycerides, back off at the muscle tissue and the fat tissue. And what happens in this process is that those big particles that are packed with the stored fat have the fat siphoned out of them. They shrink down into LDL particles that contain LDL cholesterol. And what you end up with as a result of this system is very high LDL.

They're called VLDL. And then the VLDL dropped the stored fat, the triglycerides, back off at the muscle tissue and the fat tissue. And what happens in this process is that those big particles that are packed with the stored fat have the fat siphoned out of them. They shrink down into LDL particles that contain LDL cholesterol. And what you end up with as a result of this system is very high LDL.

It's like a decay product of the thing that was transporting the energy effectively. An epiphenomenon. So yes, there are these particles that are the precursors to LDL. They drop off their cargo, the fat, at fat tissue to replenish small fat cells and muscle tissue. And then the VLDL will shrink.

It's like a decay product of the thing that was transporting the energy effectively. An epiphenomenon. So yes, there are these particles that are the precursors to LDL. They drop off their cargo, the fat, at fat tissue to replenish small fat cells and muscle tissue. And then the VLDL will shrink.

It's like a decay product of the thing that was transporting the energy effectively. An epiphenomenon. So yes, there are these particles that are the precursors to LDL. They drop off their cargo, the fat, at fat tissue to replenish small fat cells and muscle tissue. And then the VLDL will shrink.

the vldl has a lot of triglycerides in it it drops off the triglycerides and becomes an ldl which sticks around longer than the vldl so what you end up with is actually very low triglycerides because the triglycerides get sucked out so fast triglycerides are low not high your ldl ups are being very high because the vldl are being turned over really really quickly into ldl and then as an added nuance when the vldl shrink remember they're big spheres they lose surface components

the vldl has a lot of triglycerides in it it drops off the triglycerides and becomes an ldl which sticks around longer than the vldl so what you end up with is actually very low triglycerides because the triglycerides get sucked out so fast triglycerides are low not high your ldl ups are being very high because the vldl are being turned over really really quickly into ldl and then as an added nuance when the vldl shrink remember they're big spheres they lose surface components

the vldl has a lot of triglycerides in it it drops off the triglycerides and becomes an ldl which sticks around longer than the vldl so what you end up with is actually very low triglycerides because the triglycerides get sucked out so fast triglycerides are low not high your ldl ups are being very high because the vldl are being turned over really really quickly into ldl and then as an added nuance when the vldl shrink remember they're big spheres they lose surface components

from their shell, you could say, and some of that is cholesterol that gets picked up by HDL. So the result is this pattern of very high LDL, high HDL, and low triglycerides. The high LDL, the high HDL, the low triglycerides with particular thresholds is what we call lean mass hyper-responders, and is this pattern we see on lean people who go low carb.

from their shell, you could say, and some of that is cholesterol that gets picked up by HDL. So the result is this pattern of very high LDL, high HDL, and low triglycerides. The high LDL, the high HDL, the low triglycerides with particular thresholds is what we call lean mass hyper-responders, and is this pattern we see on lean people who go low carb.

from their shell, you could say, and some of that is cholesterol that gets picked up by HDL. So the result is this pattern of very high LDL, high HDL, and low triglycerides. The high LDL, the high HDL, the low triglycerides with particular thresholds is what we call lean mass hyper-responders, and is this pattern we see on lean people who go low carb.

But we can get a little bit more into the model if you want, but the point is the model starts with your metabolism shifting towards lots of fat burning. So if you put carbs back into the system, it puts the brake on the system, or at least takes the foot off the gas pedal, and your LDL should drop. That is the prediction of the model. So it should drop with any carb.