Stuart Winkler

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394 appearances 1 recordings 1 series first heard Jul 2026 last heard 23 Jul

Stuart Winkler’s voice in public audio — every appearance, attributed to the second.

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Thinking About Ob/Gyn · Episode 12.2 Cuff Dehiscence and Classic Papers · 23 Jul 2026 podcast

And really, ultimately, their work has gone.

have gone on to save at least twelve million lives.

Yeah, as most American gynecologist pedigrees do.

They go back to him.

So yeah.

Yeah.

So this is the one where they found high risk strains and included eighteen, forty-five, and fifty-six in this early study, and they were found in six point five percent and twenty six point eight percent of high grade lesions and invasive carcinomas respectively.

So t basically a little over a fourth of the invasive carcinomas had one of these

three positive.

HPV16 was associated with 47% of high-grade lesions and 47% of the cancers.

And then the intermediate risk strains were also identified in this study.

So that included 31, 33, 35, 51, 52, and 58.

And those were detected in about a quarter of the high grade lesions and in about 10% of the cancers.

They also identified some low-risk strains, so 6 and 11, which we know of as being the cause of papillomas.

And then also 42, 43, and 44.

And these were present in about 20% of low-grade lesions, but in none of the cancers.

So this was not the whole picture, and obviously testing wasn't as reliable then as it is today.

And there were a few high-risk strains that they didn't include, which we know now are oncogenic.

But this is the study that showed that HPV was largely responsible for most.

cervical cancers and that the different strains had different impact on the severity of disease.

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