The a16z Show
Episodes
Controlling AI
16 Jan 2020
Contributed by Lukas
AI can do a lot of specific tasks as well as, or even better than, humans can — for example, it can more accurately classify images, more efficientl...
Food, Drugs, and Tech—100 Years of Public Health
14 Jan 2020
Contributed by Lukas
The federal agency known as the FDA, or the Food and Drug Administration, was born over 100 years ago—at the turn of the industrial revolution, in a...
On Pharma Trends and Big Company Innovation
11 Jan 2020
Contributed by Lukas
How does the world’s largest producer of medicines in terms of volume balance the science and the business of innovation? How does an enterprise at ...
Personal Genomics: Where Are We, Really?
06 Jan 2020
Contributed by Lukas
This is a turn of the decade (and January-themed) look backward/ look forward into personal genomics, given recent and past retrospective and prospect...
Why We Should Be Optimistic About the Future
02 Jan 2020
Contributed by Lukas
Many skeptics thought the internet would never reach mass adoption, but today it’s shaping global culture, is integral to our lives -- and it's just...
What to Know about CFIUS
23 Dec 2019
Contributed by Lukas
When innovation and capital go global, so do restrictions on trade, foreign investment, and more. Over the past couple years, U.S. policymakers have e...
Are ISAs the Solution to Student Debt?
19 Dec 2019
Contributed by Lukas
A bold proposal: You go to college for free, then pay back the school after graduation—but only if you get a job in your field of study and make a h...
Shonda Rhimes on How to Create Stories (and Products) People Want
17 Dec 2019
Contributed by Lukas
Hollywood and Silicon Valley seem so different, but are more alike than we think. What challenges do tech startup founders and other creative founders...
The Journey from 0 to 1, from Mosaic to Netscape
17 Dec 2019
Contributed by Lukas
As part of a new series where we will share select a16z partner appearances on other podcasts with our audience here, this episode is cross-posted fro...
Direct Listings, Myths and Facts
11 Dec 2019
Contributed by Lukas
We’ve covered a lot of the strategic financing milestones for startups seeking to build a sustainable and enduring business -- from mindsets for sta...
The Stories and Code of Culture Change
07 Dec 2019
Contributed by Lukas
There are some common tropes that can kill your company culture -- whether it's that corporate values can be weaponized; "fake it til you make it"; th...
Of Container Ships, Supply Chains, and Retail
03 Dec 2019
Contributed by Lukas
This podcast rerun -- first recorded over two and a half years ago, now being rerun as one of our evergreen classics on the tails of the world's large...
Nursing Today, From the Bedside and Beyond
28 Nov 2019
Contributed by Lukas
"Constant attention by a good nurse may be just as important as a major operation by a surgeon”, diplomat Dag Hammarskjöld once observed -- and tha...
How We Podcast
27 Nov 2019
Contributed by Lukas
"Hi everyone, welcome to the a16z Podcast..." ... and welcome to our 500th episode, where, for the first time, we reveal behind-the-scenes details and...
Brand Building Ideas… and People
20 Nov 2019
Contributed by Lukas
Many technical founders, academics, and other experts often believe that great products -- or great ideas! -- sell themselves, without any extra effor...
Come for the Games, Stay for the Party
02 Nov 2019
Contributed by Lukas
The games industry is in the midst of a tectonic shift. Powered by platform convergence, games-as-a-service, and user-generated content, modern video ...
AI in B2B
24 Oct 2019
Contributed by Lukas
Consumer software may have adopted and incorporated AI ahead of enterprise software, where the data is more proprietary, and the market is a few thous...
Free Software and Open Source Business
21 Oct 2019
Contributed by Lukas
Today, despite the critical importance of open source to software, it’s still seen by some as blasphemous to make money as an open source business. ...
Of Emojis and Innovation
15 Oct 2019
Contributed by Lukas
This rerun podcast (first recorded in 2015, now being rerun as one of our evergreen classics/ favorites) -- is ALL about emoji. But it's really about ...
The Environment, Capitalism, Technology
04 Oct 2019
Contributed by Lukas
It used to be that the only way for humanity to grow -- and progress -- was through destroying the environment. Sure, the Industrial Revolution brough...
16 Minutes on the News #10: Amazon Healthcare, Oculus VR/AR, Google Quantum Supremacy?
30 Sep 2019
Contributed by Lukas
Our news podcast, 16 Minutes -- where we quickly cover the top headlines of the week, the a16z way (why are these topics in the news; what's real, wha...
New Business Models for Gaming, Collaboration, Creativity
28 Sep 2019
Contributed by Lukas
The combination of cloud, social, and mobile took gaming beyond a small base of just console- and PC-gamers to a massive player base. But the underlyi...
16 Minutes on the News #9: All the Recent Phone Hacks
23 Sep 2019
Contributed by Lukas
This is episode #9 of our news show, 16 Minutes, where we quickly cover recent headlines of the week, the a16z way -- why they’re in the news; why t...
a16z Podcast: The Biology of Pain
17 Sep 2019
Contributed by Lukas
What is the nature of physical pain? Why do we even experience it? Is there one type, or many? Do people experience pain differently? What is happenin...
16 Minutes on the News #8: Apple Camera, Services; Wearables - Where are We
16 Sep 2019
Contributed by Lukas
with @benedictevans @vijaypande and @smc90 This is episode #8 of our news show, 16 Minutes, where we quickly cover recent headlines of the week, the a...
a16z Podcast: How to Pay for Healthcare Based on Health
06 Sep 2019
Contributed by Lukas
There's been a lot of talk about the need for our healthcare system to shift away from volume and fee-for-service, where you pay by appointment, proce...
The Hustler's Guide to the Hair Business
06 Sep 2019
Contributed by Lukas
with @bhorowitz @shakasenghor @diishanimira @therealritabee Hustlin’ Tech is a new show (part of the a16z Podcast) that introduces the technology pl...
The Hustler's Guide to Getting Paid
06 Sep 2019
Contributed by Lukas
with @bhorowitz @shakasenghor ram @earnin & vaughn ferguson Hustlin’ Tech is a new show (part of the a16z Podcast) that introduces the technolo...
The Hustler's Guide to Preschool
06 Sep 2019
Contributed by Lukas
with @bhorowitz @shakasenghor @8ennett & sherie james Hustlin’ Tech is a new show (part of the a16z Podcast) that introduces the technology plat...
Introducing Hustlin' Tech
06 Sep 2019
Contributed by Lukas
We're excited to introduce a new podcast series hosted by a16z co-founder Ben Horowitz and Shaka Senghor, a leading voice in criminal justice reform a...
a16z Podcast: Making Culture, Making Influence -- Dapper Dan!
02 Sep 2019
Contributed by Lukas
"You cannot be IN it... and not be OF it." Dapper Dan a.k.a. Daniel Day shares his remarkable history and story of defining an era of fashio...
a16z Podcast: From the Internet's Past to the Future of Crypto
29 Aug 2019
Contributed by Lukas
What can we learn from the history of the internet for the future of crypto? In this episode of the a16z Podcast, general partner Katie Haun interview...
a16z Podcast: What to Know about FedRAMP
28 Aug 2019
Contributed by Lukas
with @ldhawke and @stevesi The government wants to get onto the cloud! But how do they assess the levels of risk in adopting specific cloud products, ...
16 Minutes on the News #7: Apple Card, BEC Scams Federal Indictment
25 Aug 2019
Contributed by Lukas
with @illscience and @smc90 This is episode #7 of our news show, 16 Minutes, where we quickly cover recent headlines of the week, the a16z way -- why ...
a16z Podcast: Software has eaten the world...and healthcare is next
15 Aug 2019
Contributed by Lukas
Back in 2011, a16z cofounder Marc Andreessen first made the bold claim that software would eat the world. In this episode (originally recorded as part...
16 Minutes on the News #6: Health Claims, Corporate Breaches
12 Aug 2019
Contributed by Lukas
with @julesyoo @smc90 This is episode #6 of our new show, 16 Minutes, where we quickly cover recent headlines of the week, the a16z way -- why they're...
16 Minutes on the News #5: Fed Real-time Payments, Death of Retail
11 Aug 2019
Contributed by Lukas
with @astrange @jeff_jordan and @smc90 This is episode #5 of our new show, 16 Minutes, where we quickly cover recent headlines of the week, the a16z w...
16 Minutes on the News: The Opioid Crisis
04 Aug 2019
Contributed by Lukas
with @jorgecondebio @vijaypande and @smc90 This is episode #4 of our new show, 16 Minutes, where we quickly cover recent headlines of the week, the a1...
16 Minutes on the News: Fortnite, Esports, Gaming, and Entertainment
04 Aug 2019
Contributed by Lukas
with @andrewchen @dcoolican and @smc90 This is episode #3 of our new show, 16 Minutes, where we quickly cover recent headlines of the week, the a16z w...
16 Minutes on the News: Mobile Malware, Drug Pricing
28 Jul 2019
Contributed by Lukas
with @martin_casado @jorgeconde @jayrughani and @smc90 This is episode #2 of our new show, 16 Minutes, where we quickly cover recent headlines of the ...
a16z Podcast: The Search for the Secret Metal that Powers All Our Devices
23 Jul 2019
Contributed by Lukas
with Kurt House (@kurtzhouse), John Thompson, Connie Chan (@conniechan) and Hanne Tidnam (@omnivorousread) The exploration for and mining of certain m...
16 Minutes on the News: Neuralink & Brain Interfaces, TikTok, FaceApp, iHeartRadio
21 Jul 2019
Contributed by Lukas
with @vijaypande @conniechan @jpm25 and @smc90 Introducing our new podcast, 16 Minutes, a short news podcast where we cover the top headlines of the w...
a16z Podcast: How To Get The Most From Your Board
19 Jul 2019
Contributed by Lukas
In this final of a 3-part series (which originally aired as YouTube videos) on working with venture investors, a16z Managing Partner Scott Kupor share...
a16z Podcast: How To Raise Money From A Venture Investor
18 Jul 2019
Contributed by Lukas
So you've decided raising venture capital is the best fundraising strategy for your startup. Now what? In this second of a 3-part series, a16z Managin...
a16z Podcast: How To Understand And Choose A Venture Investor
17 Jul 2019
Contributed by Lukas
Incentives matter. So understanding the incentives of venture capitalists will help you decide if raising money from a venture investor makes sense fo...
a16z Podcast: Beyond Software, to Talent and Culture
04 Jul 2019
Contributed by Lukas
with Marc Andreessen (@pmarca), Ben Horowitz (@bhorowitz), and Tyler Cowen (@tylercowen) Continuing our 10-year anniversary series since the founding ...
a16z Podcast: Beyond Zero Sum, Again
04 Jul 2019
Contributed by Lukas
with Marc Andreessen (@pmarca), Ben Horowitz (@bhorowitz), and Steven Johnson (@stevenbjohnson) Continuing our 10-year anniversary series since the fo...
a16z Podcast: Beyond Software Eating the World
04 Jul 2019
Contributed by Lukas
with Marc Andreessen (@pmarca), Ben Horowitz (@bhorowitz), Scott Kupor (@skupor), and Sonal Chokshi (@smc90) Continuing our 10-year anniversary series...
a16z Podcast: Beyond Disruption Theory
04 Jul 2019
Contributed by Lukas
with Marc Andreessen (@pmarca), Ben Horowitz (@bhorowitz), and Michael Copeland Continuing our 10-year anniversary series since the founding of Andree...
a16z Podcast: Entrepreneurs, Then and Now
28 Jun 2019
Contributed by Lukas
with Marc Andreessen (@pmarca), Ben Horowitz (@bhorowitz), and Stewart Butterfield (@stewart) A lot in technology -- and venture -- happens in decades...
a16z Podcast: Damage-free Genome Editing -- Next in CRISPR
26 Jun 2019
Contributed by Lukas
Two recent scientific journal papers show what's possible when CRISPR moves from cutting DNA tool to a full-fledged platform -- expanding its toolkit ...
a16z Podcast: Stories from the Frontlines of Synthetic Fraud
25 Jun 2019
Contributed by Lukas
Synthetic fraud—yes, it's a thing: a new evolution of consumer fraud that’s been emerging in financial services, to the tune of $1-$2B a year. In ...
a16z Podcast: The History and Future of Machine Learning
19 Jun 2019
Contributed by Lukas
How have we gotten to where were are with machine learning? Where are we going? a16z Operating Partner Frank Chen and Carnegie Mellon professor Tom Mi...
a16z Podcast: The Politics of Technology
15 Jun 2019
Contributed by Lukas
with Tony Blair (@InstituteGC), Scott Kupor (@skupor), and Sonal Chokshi (@smc90) If the current pace of tech change is the 21st-century equivalent ...
a16z Podcast: AI and Your Doctor, Today and Tomorrow
13 Jun 2019
Contributed by Lukas
with Eric Topol (@EricTopol) and Vijay Pande (@vijaypande) Artificial intelligence is coming to the doctor’s office. In this episode, Dr. Eric Topol...
a16z Podcast: 10+1 Lessons from Serial Entrepreneur Justin Kan
10 Jun 2019
Contributed by Lukas
Want actionable advice from a founder who has built multiple tech companies and has invested the time to be open, introspective, and transparent about...
a16z Podcast: Deep Learning for the Life Sciences
06 Jun 2019
Contributed by Lukas
with Vijay Pande (@vijaypande) and Bharath Ramsundar Deep learning has arrived in the life sciences: every week, it seems, a new published study comes...
a16z Podcast: The Power of Restorative Justice
03 Jun 2019
Contributed by Lukas
with Van Jones (@VanJones68), Shaka Senghor (@ShakaSeghnor), and Chris Lyons (@clyons) True redemption can be hard to come by in our justice system to...
a16z Podcast: The Economics of Expensive Medicines
30 May 2019
Contributed by Lukas
with Andrew Lo (@AndrewWLo) and Jorge Conde (@JorgeCondeBio) The advent of new gene and cell therapies are beginning to approach that holy grail of me...
a16z Podcast: Collectively Driving Change
27 May 2019
Contributed by Lukas
with Laurene Powell Jobs (@LaurenePowell) and Ben Horowitz (@bhorowitz) Laurene Powell Jobs is, among many other things, founder and President of the ...
a16z Podcast: What Time Is It? From Technical to Product to Sales CEO
20 May 2019
Contributed by Lukas
with David Ulevitch (@davidu) and Sonal Chokshi (@smc90) Since the startup (and founder) journey doesn't go neatly linear from technical to product to...
a16z Podcast: Five Open Problems Toward Building a Blockchain Computer
13 May 2019
Contributed by Lukas
Do you sometimes wish you had been born in a different decade so you could have worked on the fundamental building blocks of modern computing? How fun...
a16z Podcast: A Guide to Making Data-Based Decisions in Health, Parenting... and Life
11 May 2019
Contributed by Lukas
with Emily Oster (@ProfEmilyOster) and Hanne Tidnam (@omnivorousread) Are chia seeds actually that good for you? Will Vitamin E keep you healthy? Will...
a16z Podcast: Innovating in Bets
08 May 2019
Contributed by Lukas
with @annieduke, @pmarca, and @smc90 Every organization, whether small or big, early or late stage -- and every individual, whether for themselves or ...
a16z Podcast: Seven Trends in Blockchain Computing
07 May 2019
Contributed by Lukas
In a followup to one of our most popular podcast episodes which originally aired in April 2017 (https://a16z.com/2017/04/03/cryptocurrencies-protocols...
a16z Podcast: The Future Of Decision-Making—3 Startup Opportunities
29 Apr 2019
Contributed by Lukas
As companies digitize, they change the way they make decisions: decisions are made lower in the organization, based on data, and increasingly automate...
a16z Podcast: So You Wanna Build a Software Company in Healthcare?
25 Apr 2019
Contributed by Lukas
with Jorge Conde (@JorgeCondeBio), Julie Yoo (@julesyoo), and Hanne Tidnam (@omnivorousread) Building a software company in healthcare is hard -- and ...
a16z Podcast: Inside Apple Software Design
19 Apr 2019
Contributed by Lukas
Join longtime Apple software engineer Ken Kocienda in conversation with a16z Deal and Research operating partner Frank Chen for an insider’s account...
a16z Podcast: Fintech for Startups and Incumbents
04 Apr 2019
Contributed by Lukas
In this episode of the a16z Podcast -- which originally aired as a video on YouTube -- general partner Alex Rampell (and former fintech entrepreneur a...
a16z Podcast: A Podcast About Podcasting
03 Apr 2019
Contributed by Lukas
with Nick Quah (@nwquah), Connie Chan (@conniechan), and Sonal Chokshi (@smc90) It's a podcast about podcasting! About the state of the industry, that...
a16z Podcast: How Many Taps in the Apple (Plus) Tree?
30 Mar 2019
Contributed by Lukas
with Benedict Evans (@benedictevans) and Steven Sinofsky (@stevesi) What does Apple's recent event — in which a range of new services was announced,...
a16z Podcast: Incenting Innovation Inside, Loonshots to Moonshots
25 Mar 2019
Contributed by Lukas
with Safi Bahcall (@safibahcall), Vijay Pande (@vijaypande), and Sonal Chokshi (@smc90) A "moonshot" is a destination (like going to the moo...
a16z Podcast: For the Billions of Creatives Out There
16 Mar 2019
Contributed by Lukas
with Brian Koppelman (@briankoppelman), Marc Andreessen (@pmarca), and Sonal Chokshi (@smc90) The writer-showrunner is a relatively new phenomenon in ...
a16z Podcast: Lessons Learned from Chinese Education Startups
12 Mar 2019
Contributed by Lukas
When people talk about trends in education technology, they often focus on how to disrupt higher education in the U.S., whether it's about breaking fr...
a16z Podcast: What's in the Water at the George Church Lab?
26 Feb 2019
Contributed by Lukas
with George Church (@geochurch) and Jorge Conde (@JorgeCondeBio) Renowned scientist George Church is known for his groundbreaking work and methods use...
a16z Podcast: Capitalizing on an Autonomous Vehicle Future
24 Feb 2019
Contributed by Lukas
with Peter Ludwig, Qasar Younis (@qasar), and Sonal Chokshi (@smc90) When people talk about autonomous vehicles, we hear everything from "we're m...
a16z Podcast: Gaming Goes Mainstream
17 Feb 2019
Contributed by Lukas
Bobby Kotick is the CEO of Activision Blizzard (a merger he engineered); it's one of only two video gaming companies in the Fortune 500, and the large...
a16z Podcast: Who's Down with CPG, DTC? (And Micro-Brands Too?)
16 Feb 2019
Contributed by Lukas
with Ryan Caldbeck (@ryan_caldbeck), Jeff Jordan (@jeff_jordan), and Sonal Chokshi (@smc90) It's clear that all kinds of commerce companies and consum...
a16z Podcast: To All the Robots I've Loved Before
14 Feb 2019
Contributed by Lukas
with Kate Darling (@grok_) and Hanne Tidnam (@omnivorousread) We already know that we have an innate tendency to anthropomorphize robots. But beyond j...
a16z Podcast: Cryptonetworks as Emerging Economies (Done Right?)
12 Feb 2019
Contributed by Lukas
with Chris Burniske (@cburniske), Joel Monegro (@jmonegro), Denis Nazarov (@Iiterature), and Jesse Walden (@jessewldn) When designing cryptonetworks -...
a16z Podcast: Voting, Security, and Governance in Blockchains and Cryptonetworks
10 Feb 2019
Contributed by Lukas
with Phil Daian (@phildaian) and Ali Yahya (@ali01) Whether in corporations, boardrooms, or political elections, voting is something we see in all kin...
a16z Podcast: Product-Market SALES Fit (What Comes First?)
03 Feb 2019
Contributed by Lukas
with Jyoti Bansal (@jyotibansalsf), Peter Levine, Satish Talluri (@satishtalluri), and Sonal Chokshi (@smc90) One of the toughest challenges for found...
a16z Podcast: Stories and Lessons in Enterprise Sales
30 Jan 2019
Contributed by Lukas
with Mark Leslie (@mleslie45) and Peter Levine What does it actually take to win at enterprise sales? In this episode, Mark Leslie, former CEO and cha...
a16z Podcast: Finding Go-to-Market Fit in the Enterprise
30 Jan 2019
Contributed by Lukas
with Peter Levine, Bob Tinker, and Hanne Tidnam (@omnivorousread) For consumer companies, often when the holy grail of product-market fit is achieved,...
a16z Podcast: Connecting Hearts, Bodies, and Networks to Cure Cancer
26 Jan 2019
Contributed by Lukas
Veterinary oncology can inform human oncology, and vice versa -- providing a better model for looking at drug performance, interrelationships, and mor...
a16z Podcast: The Business of Cybercrime
17 Jan 2019
Contributed by Lukas
with Joel de la Garza, Jonathan Lusthaus, and Hanne Tidnam (@omnivorousread) The idea of the cybercriminal as lone wolf or hobby hacker is no longer m...
a16z Podcast: Pulse Check on Consumer Tech Trends 2019, CES and Beyond
17 Jan 2019
Contributed by Lukas
with Benedict Evans (@benedictevans) and Steven Sinofsky (@stevesi) Every year, the Consumer Electronics Show (CES) puts the latest and greatest devel...
a16z Podcast: Dark Data in Healthcare
16 Jan 2019
Contributed by Lukas
with Susannah Fox (@susannahfox), Anil Sethi (@anilsethiusa / @ciitizencorp), Vijay Pande (@vijaypande), and Sonal Chokshi (@smc90) The problem of &qu...
a16z Podcast: The Science and Business of Innovative Medicines
14 Jan 2019
Contributed by Lukas
with Vas Narasimhan (@vasnarasimhan), Jorge Conde (@jorgecondebio), Vijay Pande (@vijaypande), and Sonal Chokshi (@smc90)On average, only 1 out of 20 ...
a16z Podcast: All About Synthetic Biology
11 Jan 2019
Contributed by Lukas
with James J. Collins, Vijay Pande (@vijaypande), and Hanne Tidnam (@omnivorousread) The idea of 'designing biology' -- once science fiction -- has ov...
a16z Podcast: What’s Next for Marketplace Startups (Hint: Services)
09 Jan 2019
Contributed by Lukas
The past and future of marketplace startups -- where are we? Ever since eBay popularized an internet meeting place for buyers and sellers of, well, ju...
a16z Podcast: Talent, Tech Trends, and Culture -- with Ben, Marc, and Tyler Cowen
29 Dec 2018
Contributed by Lukas
with Marc Andreessen (@pmarca), Ben Horowitz (@bhorowitz), and Tyler Cowen (@tylercowen) This episode of the a16z Podcast features the rare combinatio...
a16z Podcast: How the Internet Happened
24 Dec 2018
Contributed by Lukas
In his book (and podcast), Brian McCullough chronicles the history and evolution of the internet -- from college kids in a basement and the dot-com bo...
a16z Podcast: All About Stablecoins
21 Dec 2018
Contributed by Lukas
with Andy Milenius (@realzandy), Jesse Walden (@jessewldn), and Sonal Chokshi (@smc90) The history, evolution, and use of money revolves around the im...
a16z Podcast: The Infrastructure of Total Health
21 Dec 2018
Contributed by Lukas
with Bernard J. Tyson (@bernardjtyson) and Ben Horowitz (@bhorowitz) Bernard J. Tyson is the chairman and CEO of Kaiser Permanente, a $73 billion non-...
a16z Podcast: Building Crypto, from Vision to Reality
18 Dec 2018
Contributed by Lukas
with Brian Armstrong (@brian_armstrong), Chris Dixon (@cdixon), and Sonal Chokshi (@smc90) Where are we, really, right now -- in terms of what we can/...
a16z Podcast: On Marrying Entertainment and Technology
05 Dec 2018
Contributed by Lukas
with Jeffrey Katzenberg, Meg Whitman (@MegWhitman), and Marc Andreessen (@pmarca) In this episode of the a16z Podcast, based on a discussion that took...
a16z Podcast: The IQ and EQ of Robots
21 Nov 2018
Contributed by Lukas
with Boris Sofman (@bsofman), Dave Touretzky (@DaveTouretzky), and Hanne Tidnam (@omnivorousread) We're just now beginning to truly see the the first ...
a16z Podcast: Ancient Dreams of Technology, Gods & Robots
19 Nov 2018
Contributed by Lukas
with Adrienne Mayor (@amayor) and Hanne Tidnam (@omnivorousread) Is it possible that ancient Greeks and Romans dreamed of technological innovations li...
a16z Podcast: M&A and Innovation, Inside Out
17 Nov 2018
Contributed by Lukas
with Stephanie Cohen and Martin Casado (@martin_casado) As chief strategy officer of Goldman Sachs (and former global head of financial sponsors M&...