The a16z Show
Episodes
Journal Club: Finding New Antibiotics with Machine Learning, What Coronavirus Structures Tell Us
26 Apr 2020
Contributed by Lukas
a16z Journal Club (part of the a16z Podcast), curates and covers recent advances from the scientific literature -- what papers we’re reading, and wh...
Introducing Journal Club
26 Apr 2020
Contributed by Lukas
Announcing a16z Journal Club, a new show where we curate and discuss recent research papers with a16z experts and others. This new show continues the...
What the Narrow Waist of the Internet Means for Innovation Today
24 Apr 2020
Contributed by Lukas
Here is Ali's tweetstorm on the Narrow Waist of Blockchain Computing Stay Updated:Find a16z on XFind a16z on LinkedInListen to the a16z Podcast on S...
IT'S TIME TO BUILD
21 Apr 2020
Contributed by Lukas
“It's Time to Build” by Marc Andreessen. You can also find and share this essay at a16z.com/build Stay Updated:Find a16z on XFind a16z on LinkedI...
Introducing Read Alouds
21 Apr 2020
Contributed by Lukas
We wanted to let you know about a special new series of posts occasionally read out loud from us (you can learn more about the why and why now in ep...
The Passion Economy: Redefining Work
18 Apr 2020
Contributed by Lukas
This episode of the a16z Podcast covers the the rise of online platforms that enable people to make a living off their unique interests and skills. It...
When Bad Policy = Bad Business Models = Bad Public Health
16 Apr 2020
Contributed by Lukas
with @JorgeCondeBio, @julesyoo, and @omnivorousreadIn some ways, the coronavirus feels like it came out of nowhere—a kind of Black Swan event. But a...
Moving to Remote Development (and Work)
15 Apr 2020
Contributed by Lukas
From agile project management to asynchronous collaboration, development teams have pioneered many of the tools and best practices for remote work. Ho...
Virtual Oncology
10 Apr 2020
Contributed by Lukas
with @vintweeta @pbcancerdoc @sumitshahmd @omnivorousreadCoronavirus is now disrupting the entire health care system, not just because of the burden o...
The Story of Schizophrenia
07 Apr 2020
Contributed by Lukas
Descriptions of the mental illness we today call schizophrenia are as old as humankind itself. And more than likely, we are are all familiar with this...
Navigating the Numbers
04 Apr 2020
Contributed by Lukas
For any business, there are three core financial statements – the income or P&L statement, the balance sheet, and the cash flow statement. While the...
Gaming and Livestreaming: Connecting While Distancing
02 Apr 2020
Contributed by Lukas
Since social distancing measures were first put in place, time spent gaming has gone up—way up. According to a recent report by Verizon, video game ...
The Hustlers's Guide to Suing the Man
01 Apr 2020
Contributed by Lukas
This is the next cycle (Q1 2020) of Hustlin' Tech, a podcast series (from the a16z Podcast) about technology platforms that create opportunities for p...
The Hustler's Guide to Elder Care
01 Apr 2020
Contributed by Lukas
This is the next cycle (Q1 2020) of Hustlin' Tech, a podcast series (from the a16z Podcast) about technology platforms that create opportunities for p...
The Hustler's Guide to Nursing Jobs
30 Mar 2020
Contributed by Lukas
This is the next cycle (Q1 2020) of Hustlin' Tech, a podcast series (from the a16z Podcast) about technology platforms that create opportunities for p...
Hustlin' Tech, Round Two
30 Mar 2020
Contributed by Lukas
This is the next cycle of Hustlin' Tech -- a podcast series co-hosted by bestselling authors, a16z co-founder Ben Horowitz; and Shaka Senghor, a leadi...
Security When the Workforce Goes Remote
27 Mar 2020
Contributed by Lukas
We are in the midst of a rapid and unprecedented shift to remote work. What does it mean for security when the airgap between work and life is gone? H...
The Delivery-Optimized Future of Food
25 Mar 2020
Contributed by Lukas
The spike in online ordering and food delivery—a trend that's particularly relevant now—is evidence of how tech is fundamentally changing how and ...
Remote Work and Our New Reality
23 Mar 2020
Contributed by Lukas
Stay Updated:Find a16z on XFind a16z on LinkedInListen to the a16z Podcast on SpotifyListen to the a16z Podcast on Apple PodcastsFollow our host: http...
When Medicine Goes Virtual
19 Mar 2020
Contributed by Lukas
We’re at a moment where we are now seeing medicine go virtual faster, and at a scale that it has never done before. In this conversation, a16z ...
Labs for Diagnostics: Then, Now, and Next
17 Mar 2020
Contributed by Lukas
A lot's going on in the world of healthcare right now, and one topic that's especially relevant is how diagnostic labs work. In this episode with Dave...
How a16z's Crypto Startup School Went Remote
14 Mar 2020
Contributed by Lukas
On February 21, Andreessen Horowitz kicked off its very first Crypto Startup School, with 45 students from around the U.S. and three countries gatheri...
When Fintech Meets Social
12 Mar 2020
Contributed by Lukas
The last financial crisis prompted many consumers to reassess their banking expectations—none more so than millennials and Gen-Z-ers. While revealin...
Innovation Through Software Development and IT
06 Mar 2020
Contributed by Lukas
One of the recurring themes we talk about a lot on the a16z Podcast is how software changes organizations, and vice versa... More broadly: it’s real...
The Open Source CIO
28 Feb 2020
Contributed by Lukas
In 2014, in "Why There Will Never Be Another Red Hat," Peter Levine argued that Red Hat’s open source business model of commercializing support and ...
Novel Coronavirus Updates: How Healthcare System, Tests Work; More
27 Feb 2020
Contributed by Lukas
This episode covers the following -- since our previous deep-dive on the novel coronavirus outbreak -- including:practical implications for the U.S. h...
Metrics and Mindsets for Retention & Engagement
20 Feb 2020
Contributed by Lukas
It's "Marketplaces Week" for us at a16z, thanks to our consumer team releasing a new index of the next industry-defining marketplaces, the Marketplace...
Tough Love, Global Diplomacy, and Lessons on Leadership
14 Feb 2020
Contributed by Lukas
Susan shares how she learned to leverage the characteristics of her personality early in her career as assistant secretary of state [2:05]One of the i...
Building the First CAR T Company
07 Feb 2020
Contributed by Lukas
with @OzAzamTmunity1, @JorgeCondeBio, and @omnivorousreadCAR T therapy, the groundbreaking new medicines that uses engineered T-cells to attack cancer...
Rebel Talent
04 Feb 2020
Contributed by Lukas
When we think about rebellious behavior in the context of organizations and companies, we tend to think of rebels as trouble-makers, rabble-rousers; i...
All about the Coronavirus
30 Jan 2020
Contributed by Lukas
This episode of 16 Minutes on the news from a16z is all about the recent coronavirus outbreak -- or rather, a new type of coronavirus called 2019-nCoV...
The Truth about 1000 True Fans + Pricing Our Attention
27 Jan 2020
Contributed by Lukas
The idea of "1000 true fans" -- first proposed by Kevin Kelly in 2008 and later updated for Tools of Titans -- argued that to be a successful creator,...
Writers Writing, Readers Reading, Creators Creating
27 Jan 2020
Contributed by Lukas
We've been financing good writing with bad advertising -- and "attention monsters" (to quote Craig Mod) for way too long. So what happens when the tec...
What's Next for the Internet?
19 Jan 2020
Contributed by Lukas
How can we evolve the web for a better future? Has the web become a mature platform — or are we still in the early days of knowing what it can do an...
Controlling AI
16 Jan 2020
Contributed by Lukas
AI can do a lot of specific tasks as well as, or even better than, humans can — for example, it can more accurately classify images, more efficientl...
Food, Drugs, and Tech—100 Years of Public Health
14 Jan 2020
Contributed by Lukas
The federal agency known as the FDA, or the Food and Drug Administration, was born over 100 years ago—at the turn of the industrial revolution, in a...
On Pharma Trends and Big Company Innovation
11 Jan 2020
Contributed by Lukas
How does the world’s largest producer of medicines in terms of volume balance the science and the business of innovation? How does an enterprise at ...
Personal Genomics: Where Are We, Really?
06 Jan 2020
Contributed by Lukas
This is a turn of the decade (and January-themed) look backward/ look forward into personal genomics, given recent and past retrospective and prospect...
Why We Should Be Optimistic About the Future
02 Jan 2020
Contributed by Lukas
Many skeptics thought the internet would never reach mass adoption, but today it’s shaping global culture, is integral to our lives -- and it's just...
What to Know about CFIUS
23 Dec 2019
Contributed by Lukas
When innovation and capital go global, so do restrictions on trade, foreign investment, and more. Over the past couple years, U.S. policymakers have e...
Are ISAs the Solution to Student Debt?
19 Dec 2019
Contributed by Lukas
A bold proposal: You go to college for free, then pay back the school after graduation—but only if you get a job in your field of study and make a h...
Shonda Rhimes on How to Create Stories (and Products) People Want
17 Dec 2019
Contributed by Lukas
Hollywood and Silicon Valley seem so different, but are more alike than we think. What challenges do tech startup founders and other creative founders...
The Journey from 0 to 1, from Mosaic to Netscape
17 Dec 2019
Contributed by Lukas
As part of a new series where we will share select a16z partner appearances on other podcasts with our audience here, this episode is cross-posted fro...
Direct Listings, Myths and Facts
11 Dec 2019
Contributed by Lukas
We’ve covered a lot of the strategic financing milestones for startups seeking to build a sustainable and enduring business -- from mindsets for sta...
The Stories and Code of Culture Change
07 Dec 2019
Contributed by Lukas
There are some common tropes that can kill your company culture -- whether it's that corporate values can be weaponized; "fake it til you make it"; th...
Of Container Ships, Supply Chains, and Retail
03 Dec 2019
Contributed by Lukas
This podcast rerun -- first recorded over two and a half years ago, now being rerun as one of our evergreen classics on the tails of the world's large...
Nursing Today, From the Bedside and Beyond
28 Nov 2019
Contributed by Lukas
"Constant attention by a good nurse may be just as important as a major operation by a surgeon”, diplomat Dag Hammarskjöld once observed -- and tha...
How We Podcast
27 Nov 2019
Contributed by Lukas
"Hi everyone, welcome to the a16z Podcast..." ... and welcome to our 500th episode, where, for the first time, we reveal behind-the-scenes details and...
Brand Building Ideas… and People
20 Nov 2019
Contributed by Lukas
Many technical founders, academics, and other experts often believe that great products -- or great ideas! -- sell themselves, without any extra effor...
Come for the Games, Stay for the Party
02 Nov 2019
Contributed by Lukas
The games industry is in the midst of a tectonic shift. Powered by platform convergence, games-as-a-service, and user-generated content, modern video ...
AI in B2B
24 Oct 2019
Contributed by Lukas
Consumer software may have adopted and incorporated AI ahead of enterprise software, where the data is more proprietary, and the market is a few thous...
Free Software and Open Source Business
21 Oct 2019
Contributed by Lukas
Today, despite the critical importance of open source to software, it’s still seen by some as blasphemous to make money as an open source business. ...
Of Emojis and Innovation
15 Oct 2019
Contributed by Lukas
This rerun podcast (first recorded in 2015, now being rerun as one of our evergreen classics/ favorites) -- is ALL about emoji. But it's really about ...
The Environment, Capitalism, Technology
04 Oct 2019
Contributed by Lukas
It used to be that the only way for humanity to grow -- and progress -- was through destroying the environment. Sure, the Industrial Revolution brough...
16 Minutes on the News #10: Amazon Healthcare, Oculus VR/AR, Google Quantum Supremacy?
30 Sep 2019
Contributed by Lukas
Our news podcast, 16 Minutes -- where we quickly cover the top headlines of the week, the a16z way (why are these topics in the news; what's real, wha...
New Business Models for Gaming, Collaboration, Creativity
28 Sep 2019
Contributed by Lukas
The combination of cloud, social, and mobile took gaming beyond a small base of just console- and PC-gamers to a massive player base. But the underlyi...
16 Minutes on the News #9: All the Recent Phone Hacks
23 Sep 2019
Contributed by Lukas
This is episode #9 of our news show, 16 Minutes, where we quickly cover recent headlines of the week, the a16z way -- why they’re in the news; why t...
a16z Podcast: The Biology of Pain
17 Sep 2019
Contributed by Lukas
What is the nature of physical pain? Why do we even experience it? Is there one type, or many? Do people experience pain differently? What is happenin...
16 Minutes on the News #8: Apple Camera, Services; Wearables - Where are We
16 Sep 2019
Contributed by Lukas
with @benedictevans @vijaypande and @smc90 This is episode #8 of our news show, 16 Minutes, where we quickly cover recent headlines of the week, the a...
a16z Podcast: How to Pay for Healthcare Based on Health
06 Sep 2019
Contributed by Lukas
There's been a lot of talk about the need for our healthcare system to shift away from volume and fee-for-service, where you pay by appointment, proce...
The Hustler's Guide to the Hair Business
06 Sep 2019
Contributed by Lukas
with @bhorowitz @shakasenghor @diishanimira @therealritabee Hustlin’ Tech is a new show (part of the a16z Podcast) that introduces the technology pl...
The Hustler's Guide to Getting Paid
06 Sep 2019
Contributed by Lukas
with @bhorowitz @shakasenghor ram @earnin & vaughn ferguson Hustlin’ Tech is a new show (part of the a16z Podcast) that introduces the technolo...
The Hustler's Guide to Preschool
06 Sep 2019
Contributed by Lukas
with @bhorowitz @shakasenghor @8ennett & sherie james Hustlin’ Tech is a new show (part of the a16z Podcast) that introduces the technology plat...
Introducing Hustlin' Tech
06 Sep 2019
Contributed by Lukas
We're excited to introduce a new podcast series hosted by a16z co-founder Ben Horowitz and Shaka Senghor, a leading voice in criminal justice reform a...
a16z Podcast: Making Culture, Making Influence -- Dapper Dan!
02 Sep 2019
Contributed by Lukas
"You cannot be IN it... and not be OF it." Dapper Dan a.k.a. Daniel Day shares his remarkable history and story of defining an era of fashio...
a16z Podcast: From the Internet's Past to the Future of Crypto
29 Aug 2019
Contributed by Lukas
What can we learn from the history of the internet for the future of crypto? In this episode of the a16z Podcast, general partner Katie Haun interview...
a16z Podcast: What to Know about FedRAMP
28 Aug 2019
Contributed by Lukas
with @ldhawke and @stevesi The government wants to get onto the cloud! But how do they assess the levels of risk in adopting specific cloud products, ...
16 Minutes on the News #7: Apple Card, BEC Scams Federal Indictment
25 Aug 2019
Contributed by Lukas
with @illscience and @smc90 This is episode #7 of our news show, 16 Minutes, where we quickly cover recent headlines of the week, the a16z way -- why ...
a16z Podcast: Software has eaten the world...and healthcare is next
15 Aug 2019
Contributed by Lukas
Back in 2011, a16z cofounder Marc Andreessen first made the bold claim that software would eat the world. In this episode (originally recorded as part...
16 Minutes on the News #6: Health Claims, Corporate Breaches
12 Aug 2019
Contributed by Lukas
with @julesyoo @smc90 This is episode #6 of our new show, 16 Minutes, where we quickly cover recent headlines of the week, the a16z way -- why they're...
16 Minutes on the News #5: Fed Real-time Payments, Death of Retail
11 Aug 2019
Contributed by Lukas
with @astrange @jeff_jordan and @smc90 This is episode #5 of our new show, 16 Minutes, where we quickly cover recent headlines of the week, the a16z w...
16 Minutes on the News: The Opioid Crisis
04 Aug 2019
Contributed by Lukas
with @jorgecondebio @vijaypande and @smc90 This is episode #4 of our new show, 16 Minutes, where we quickly cover recent headlines of the week, the a1...
16 Minutes on the News: Fortnite, Esports, Gaming, and Entertainment
04 Aug 2019
Contributed by Lukas
with @andrewchen @dcoolican and @smc90 This is episode #3 of our new show, 16 Minutes, where we quickly cover recent headlines of the week, the a16z w...
16 Minutes on the News: Mobile Malware, Drug Pricing
28 Jul 2019
Contributed by Lukas
with @martin_casado @jorgeconde @jayrughani and @smc90 This is episode #2 of our new show, 16 Minutes, where we quickly cover recent headlines of the ...
a16z Podcast: The Search for the Secret Metal that Powers All Our Devices
23 Jul 2019
Contributed by Lukas
with Kurt House (@kurtzhouse), John Thompson, Connie Chan (@conniechan) and Hanne Tidnam (@omnivorousread) The exploration for and mining of certain m...
16 Minutes on the News: Neuralink & Brain Interfaces, TikTok, FaceApp, iHeartRadio
21 Jul 2019
Contributed by Lukas
with @vijaypande @conniechan @jpm25 and @smc90 Introducing our new podcast, 16 Minutes, a short news podcast where we cover the top headlines of the w...
a16z Podcast: How To Get The Most From Your Board
19 Jul 2019
Contributed by Lukas
In this final of a 3-part series (which originally aired as YouTube videos) on working with venture investors, a16z Managing Partner Scott Kupor share...
a16z Podcast: How To Raise Money From A Venture Investor
18 Jul 2019
Contributed by Lukas
So you've decided raising venture capital is the best fundraising strategy for your startup. Now what? In this second of a 3-part series, a16z Managin...
a16z Podcast: How To Understand And Choose A Venture Investor
17 Jul 2019
Contributed by Lukas
Incentives matter. So understanding the incentives of venture capitalists will help you decide if raising money from a venture investor makes sense fo...
a16z Podcast: Beyond Software, to Talent and Culture
04 Jul 2019
Contributed by Lukas
with Marc Andreessen (@pmarca), Ben Horowitz (@bhorowitz), and Tyler Cowen (@tylercowen) Continuing our 10-year anniversary series since the founding ...
a16z Podcast: Beyond Zero Sum, Again
04 Jul 2019
Contributed by Lukas
with Marc Andreessen (@pmarca), Ben Horowitz (@bhorowitz), and Steven Johnson (@stevenbjohnson) Continuing our 10-year anniversary series since the fo...
a16z Podcast: Beyond Software Eating the World
04 Jul 2019
Contributed by Lukas
with Marc Andreessen (@pmarca), Ben Horowitz (@bhorowitz), Scott Kupor (@skupor), and Sonal Chokshi (@smc90) Continuing our 10-year anniversary series...
a16z Podcast: Beyond Disruption Theory
04 Jul 2019
Contributed by Lukas
with Marc Andreessen (@pmarca), Ben Horowitz (@bhorowitz), and Michael Copeland Continuing our 10-year anniversary series since the founding of Andree...
a16z Podcast: Entrepreneurs, Then and Now
28 Jun 2019
Contributed by Lukas
with Marc Andreessen (@pmarca), Ben Horowitz (@bhorowitz), and Stewart Butterfield (@stewart) A lot in technology -- and venture -- happens in decades...
a16z Podcast: Damage-free Genome Editing -- Next in CRISPR
26 Jun 2019
Contributed by Lukas
Two recent scientific journal papers show what's possible when CRISPR moves from cutting DNA tool to a full-fledged platform -- expanding its toolkit ...
a16z Podcast: Stories from the Frontlines of Synthetic Fraud
25 Jun 2019
Contributed by Lukas
Synthetic fraud—yes, it's a thing: a new evolution of consumer fraud that’s been emerging in financial services, to the tune of $1-$2B a year. In ...
a16z Podcast: The History and Future of Machine Learning
19 Jun 2019
Contributed by Lukas
How have we gotten to where were are with machine learning? Where are we going? a16z Operating Partner Frank Chen and Carnegie Mellon professor Tom Mi...
a16z Podcast: The Politics of Technology
15 Jun 2019
Contributed by Lukas
with Tony Blair (@InstituteGC), Scott Kupor (@skupor), and Sonal Chokshi (@smc90) If the current pace of tech change is the 21st-century equivalent ...
a16z Podcast: AI and Your Doctor, Today and Tomorrow
13 Jun 2019
Contributed by Lukas
with Eric Topol (@EricTopol) and Vijay Pande (@vijaypande) Artificial intelligence is coming to the doctor’s office. In this episode, Dr. Eric Topol...
a16z Podcast: 10+1 Lessons from Serial Entrepreneur Justin Kan
10 Jun 2019
Contributed by Lukas
Want actionable advice from a founder who has built multiple tech companies and has invested the time to be open, introspective, and transparent about...
a16z Podcast: Deep Learning for the Life Sciences
06 Jun 2019
Contributed by Lukas
with Vijay Pande (@vijaypande) and Bharath Ramsundar Deep learning has arrived in the life sciences: every week, it seems, a new published study comes...
a16z Podcast: The Power of Restorative Justice
03 Jun 2019
Contributed by Lukas
with Van Jones (@VanJones68), Shaka Senghor (@ShakaSeghnor), and Chris Lyons (@clyons) True redemption can be hard to come by in our justice system to...
a16z Podcast: The Economics of Expensive Medicines
30 May 2019
Contributed by Lukas
with Andrew Lo (@AndrewWLo) and Jorge Conde (@JorgeCondeBio) The advent of new gene and cell therapies are beginning to approach that holy grail of me...
a16z Podcast: Collectively Driving Change
27 May 2019
Contributed by Lukas
with Laurene Powell Jobs (@LaurenePowell) and Ben Horowitz (@bhorowitz) Laurene Powell Jobs is, among many other things, founder and President of the ...
a16z Podcast: What Time Is It? From Technical to Product to Sales CEO
20 May 2019
Contributed by Lukas
with David Ulevitch (@davidu) and Sonal Chokshi (@smc90) Since the startup (and founder) journey doesn't go neatly linear from technical to product to...
a16z Podcast: Five Open Problems Toward Building a Blockchain Computer
13 May 2019
Contributed by Lukas
Do you sometimes wish you had been born in a different decade so you could have worked on the fundamental building blocks of modern computing? How fun...
a16z Podcast: A Guide to Making Data-Based Decisions in Health, Parenting... and Life
11 May 2019
Contributed by Lukas
with Emily Oster (@ProfEmilyOster) and Hanne Tidnam (@omnivorousread) Are chia seeds actually that good for you? Will Vitamin E keep you healthy? Will...
a16z Podcast: Innovating in Bets
08 May 2019
Contributed by Lukas
with @annieduke, @pmarca, and @smc90 Every organization, whether small or big, early or late stage -- and every individual, whether for themselves or ...
a16z Podcast: Seven Trends in Blockchain Computing
07 May 2019
Contributed by Lukas
In a followup to one of our most popular podcast episodes which originally aired in April 2017 (https://a16z.com/2017/04/03/cryptocurrencies-protocols...
a16z Podcast: The Future Of Decision-Making—3 Startup Opportunities
29 Apr 2019
Contributed by Lukas
As companies digitize, they change the way they make decisions: decisions are made lower in the organization, based on data, and increasingly automate...