To Health With That! MTHFR Mutations and Methylation.
Episodes
S2E19: MTHFR and Anxiety
09 Jan 2022
Contributed by Lukas
MTHFR and anxiety are intimately linked, as we have explored in other episodes. Please visit the full show notes here if you'd like links to those epi...
S2E18: The MTHFR Lifestyle
02 Jan 2022
Contributed by Lukas
I mention it a *lot* but what is the MTHFR Lifestyle? Here is your chance to find out. We'll discuss what a good lifestyle really means and why we hav...
S2E17: Happy Holidays and New Years Resolutions
26 Dec 2021
Contributed by Lukas
Let's face it, 2021 has been difficult for a lot of us. Let's make 2022 a year with more joy, more happiness, and more ease. Thank you so much for bei...
Hydration Matters for MTHFR
19 Dec 2021
Contributed by Lukas
Water is so talked about that it has become a non-answer for everything. Nobody pays attention because it's just too simple. Well, let's talk about th...
S2E15: What To Do When You're Having Detox Symptoms
12 Dec 2021
Contributed by Lukas
Detox symptoms are a thing that happens to us. Hopefully, two weeks ago you started thinking about how to recognize them. Now, let's discuss the...
S2E13: Patterns in Symptom Tracking
28 Nov 2021
Contributed by Lukas
I know - I can hear you rolling your eyes, but symptom tracking makes a huge difference, so let's talk about it a little bit more. This week we'll dis...
S2E12: Week One of Methylfolate and a Bit About Backlog
21 Nov 2021
Contributed by Lukas
Congratulations! If you've been following along with the show, then you're one week into your 5-LMTHF start. It may have been a great success, y...
S2E11: The Methylfolate Start
14 Nov 2021
Contributed by Lukas
Finally, we're here! It's what we've all been waiting for. So let's talk about: Dealbreaker scenarios to watch for that mean you might not tol...
S2E10: Why Starting 5-LMTHF Can Cause Symptoms
07 Nov 2021
Contributed by Lukas
Normally, starting a supplement is a piece of cake, but that isn't always the case with 5-LMTHF. But why is this one so different? This week we'll tal...
S2E9: MTHFR Listener Questions Oct. 2021
31 Oct 2021
Contributed by Lukas
You've got questions and I've got answers, or at least theories. This week we'll talk about: What type of blood testing should MTHFR folks be doing ...
S2E8: The Preliminaries with MTHFR
24 Oct 2021
Contributed by Lukas
The MTHFR journey happens in three phases and the one we're in I like to call the Preliminaries. This is where we prime your system for the big flood ...
S2E7: B12 and MTHFR
17 Oct 2021
Contributed by Lukas
Most B vitamins are great with MTHFR. No big issues and they generally make us feel better. There is one, however, that is a bit tricky and that...
S2E6: The Other B Vitamins for MTHFR
10 Oct 2021
Contributed by Lukas
Sure, "folate" is in the name of this mutation, but the most common mistake I see MTHFR folks make is thinking that it's all about folate. This episod...
S2E5: Patience on the MTHFR Journey
03 Oct 2021
Contributed by Lukas
Patience is thin on the ground for MTHFR folks, which is ironic, because it's the thing we need most on our path to health. This week we'll talk about...
S2E4: Adding High Folate Foods
26 Sep 2021
Contributed by Lukas
We are moving through the very baby beginnings of the MTHFR journey. Before you add in any fancy supplements or methylation boosters, we're going to t...
S2E3: MTHFR and Food Cravings
19 Sep 2021
Contributed by Lukas
Food cravings can have a hidden wisdom and some of you may have noticed some of them coming up if you've just eliminated the folic acid foods from you...
S2E2: Getting Toxic Folic Acid, Out.
12 Sep 2021
Contributed by Lukas
In typical Amy fashion, this week I'm doing my best to scare all of you dear listeners away by giving you the hardest possible task up front: getting ...
S2E1: Preparing to Get Healthy With MTHFR
07 Sep 2021
Contributed by Lukas
Welcome back to To Health With That! Season two is going to be a typical MTHFR journey, step by step. We will walk through the entire process of worki...
Season 2 Preview.
01 Aug 2021
Contributed by Lukas
Season One has been amazing. So much information from a very academic standpoint, but what about practical application? I want you to enjoy a beautifu...
Empty Bucket, Fix Backlog
25 Jul 2021
Contributed by Lukas
This sounds like the MTHFR version of a Zen slogan... Chop wood, carry water. Empty bucket, fix backlog. It could easily be the mantra we live b...
Why Does My Methylfolate Dose Change So Much?
18 Jul 2021
Contributed by Lukas
MTHFR can be a strange and wonderful journey, and the only real constant is change. But why? Why do doses change so much? This week, we'll talk ...
What Causes Bad Days? The Bucket and The Backlog
11 Jul 2021
Contributed by Lukas
When you're working with MTHFR and following a good plan, you start to feel better from day one. But that doesn't mean that day 38 isn't kind of icky....
How Do You Know When Your Methylation Is Balanced With MTHFR?
04 Jul 2021
Contributed by Lukas
This is a big journey - how do you know when you're there? In good news, there are two main ways. This week, we'll talk about: Signs and behaviors t...
MTHFR Questions From Listeners
27 Jun 2021
Contributed by Lukas
This week we've got some questions from listeners - all about MTHFR. We'll talk about: What to do if you want to work with Amy. The three different...
MTHFR and Joyhacks - Simple Steps to Boost Your Happy.
20 Jun 2021
Contributed by Lukas
We've all heard so many things we're supposed to do to be happy, but do you know anybody who actually does them? This week we'll talk about simp...
MTHFR and Neurotransmitters - Amy's Neurotransmitter Theory
13 Jun 2021
Contributed by Lukas
Research has mostly shown that mental health issues often correlate with imbalance in neurotransmitters and so that idea has been locked in socially. ...
MTHFR and Norepinephrine
06 Jun 2021
Contributed by Lukas
One more episode in our mini-series on neurotransmitters, MTHFR also affects your levels of norepinephrine and its metabolite, epinephrine. We'll disc...
MTHFR and Dopamine
30 May 2021
Contributed by Lukas
In our little mini-series on MTHFR and neurotransmitters, we'll move on to discuss the relationship between MTHFR and dopamine. We'll talk about: Th...
Neurotransmitters: Serotonin and MTHFR
23 May 2021
Contributed by Lukas
MTHFR is tangled up with neurotransmitters via its direct link with the BH4 pathway, which is where most neurotransmitters are made. So let's talk abo...
MTHFR and Decision Fatigue
16 May 2021
Contributed by Lukas
Decision fatigue is the weary, burned out feeling that comes from the constant burden of too many choices. Simple choices and consequential ones all a...
The Best B12 for MTHFR Mutants
09 May 2021
Contributed by Lukas
This is our most frequently asked question in Genetic Rockstars, the MTHFR community, so I figured we'd better have a conversation about it. This week...
Omega-3 Fatty Acids and Gene Expression in MTHFR
02 May 2021
Contributed by Lukas
These two amazing research studies are actually measuring how active the MTHFR gene is and how Omega-3 fatty acids from fish oils change that. We'll t...
The Magical Relationship Between B Vitamins and Fish Oils
25 Apr 2021
Contributed by Lukas
Research is starting to show that some magic happens between B vitamins and fish oils, or omega-3 fatty acids, that allows the two of them together to...
Lowering Your Homocysteine With MTHFR
18 Apr 2021
Contributed by Lukas
We've talked about the risks of homocysteine and optimal levels and even the link between Covid-19 disease severity and Homocysteine, so now, le...
Homocysteine By The Numbers
11 Apr 2021
Contributed by Lukas
Ok - so we get that homocysteine is a problem for MTHFR folks. But what levels are we talking about here? In this episode we'll talk about: Importan...
MTHFR and Covid-19 - What We Know Now.
05 Apr 2021
Contributed by Lukas
In good-ish news, Covid-19 has been around long enough for us to get some DNA-specific research into the mix. Not much research has been done yet on C...
Methionine, homocysteine, and MTHFR.
28 Mar 2021
Contributed by Lukas
It's really easy to get into the mindset that methionine is "good" and homocysteine is "bad" but the truth is so much more interesting than that! Let'...
MTHFR and Homocysteine - The Basics
21 Mar 2021
Contributed by Lukas
Homocysteine is usually the first thing that tips you or your doctor off to the fact that there may be an MTHFR mutation or an issue somewhere else in...
Detox for MTHFR, Revisited
14 Mar 2021
Contributed by Lukas
We've had a few conversations about detox, but let's revisit some of these concepts in greater detail. This week we'll talk about: The symptoms that...
What To Expect When You're Breaking Mental Bad Habits
07 Mar 2021
Contributed by Lukas
Last week we talked about the idea of breaking mental bad habits and I gave you three tools you can use. The Fantasy The Stop and Drop The Distra...
The Genius of Overmethylators
03 Mar 2021
Contributed by Lukas
Let's talk about Overmethylation. Do overmethylators even need to have the MTHFR mutation? Unique gifts overmethylators bring to the world and the ...
Mental Bad Habits
28 Feb 2021
Contributed by Lukas
This week we're expanding on the conversation about other factors in depression and talking about the single most overlooked factor in mental health -...
MTHFR and Depression
21 Feb 2021
Contributed by Lukas
Depression isn't an MTHFR problem, it's a human problem. Having said that, there are lots of ways MTHFR can contribute and the best news is, they're m...
The Genius of Undermethylators
14 Feb 2021
Contributed by Lukas
Undermethylation is the most common MTHFR basic state, and it has its own unique strengths, challenges, and reactions to the world. In this episode yo...
Stages of Healing with MTHFR
31 Jan 2021
Contributed by Lukas
Healing can be a messy process, but by using a systematic approach you can avoid some of the craziness. In this episode we'll talk about: Supplement...
The Bucket Theory and MTHFR
24 Jan 2021
Contributed by Lukas
This week will help you to get a mental image of how all of your tiny stressors end up turning into symptoms your body. It's an MTHFR fairy tale (don'...
MTHFR and Allergies or Sensitivities
17 Jan 2021
Contributed by Lukas
Let's face it - MTHFR goes hand in hand with allergies and sensitivities in a number of different forms. In this episode, we'll talk about: The four...
MTHFR and Pain Medications
10 Jan 2021
Contributed by Lukas
This episode resulted from a great question from listener Jane Turner - thanks, Jane! We'll talk about: MTHFR and Tylenol (or paracetamol, or acetam...
A1298C Mutation
20 Dec 2020
Contributed by Lukas
The internets get hugely focused on particular mutations, so here's my nod to A1298C. In this episode we'll talk about: What makes a difference in y...
All About C677T Mutation
13 Dec 2020
Contributed by Lukas
This episode might surprise you! This week we'll go over: The bizarre and confusing array of names for the C677T mutation The gaps in current resea...
Gentle Detox Strategies for MTHFR Mutants
06 Dec 2020
Contributed by Lukas
Detox is for life, at least it is if you, like me, have an MTHFR situation. In this episode we'll discuss: Why detox kits are not always the best fo...
What Is The Goal With MTHFR?
29 Nov 2020
Contributed by Lukas
It's important to keep the goals in mind when you're working with MTHFR, but... what are they? We'll talk about: Three concrete health goals to work...
What to Expect When You Start Methylfolate
22 Nov 2020
Contributed by Lukas
Starting methylfolate can be a rocky road, so it helps to know what is a normal part of starting and what is a signal that something has gone wrong so...
Dosing Strategies for 5-LMTHF.
08 Nov 2020
Contributed by Lukas
Dosing 5-LMTHF isn't typically just finding a right dose and sticking with it until you die. Typically, you have to be able to roll with the pun...
I Have MTHFR - How Do I Start Taking 5-LMTHF?
01 Nov 2020
Contributed by Lukas
This is, of course, what everybody wants to know first thing out of the gate, before they do anything else with MTHFR, so let's talk about it. This we...
Choline, Magnesium and Zinc for MTHFR
25 Oct 2020
Contributed by Lukas
Of course MTHFR is about folate, but the whole methylation pathway is so vital to your health, that lots of other nutrients are tied up in this proces...
Knowing Your Own MTHFR Red Flags, And Whether You're Moving To Health or Disease.
18 Oct 2020
Contributed by Lukas
The question of whether you're moving to health or disease is a silly one, right? Of course you know. Except with MTHFR, this might be tricker than yo...
I Can't Take Folate - Now What?
11 Oct 2020
Contributed by Lukas
Folate is supposed to cure what ails you with MTHFR, so what happens if you just don't tolerate it... at all? This is a problem lots of MTHFR folks fa...
Your Basic State - Overmethylator, Undermethylator or Methylation Neutral
04 Oct 2020
Contributed by Lukas
This is a topic of some debate among the MTHFR community, and one area where Dr. Ben Lynch and I have differing opinions. In this episode we will deep...
Energy, Fatigue, and MTHFR.
28 Sep 2020
Contributed by Lukas
MTHFR has its sticky fingers in almost everything and energy is no exception. Fatigue is one of the most common symptoms that MTHFR folks experience, ...
MTHFR and Glutathione
20 Sep 2020
Contributed by Lukas
Glutathione is called the "master antioxidant," which sounds important, so obviously the MTHFR polymorphism is going to mess it up. In this episode we...
It's Not All About Folate and Amy's MTHFR Journey
13 Sep 2020
Contributed by Lukas
Even though we talk about folate *constantly* and don't seem to talk about any other vitamins, it isn't just about the folate. In this episode, we'll ...
Methylfolate, or a High-Folate Diet Makes Me Feel BAD.
06 Sep 2020
Contributed by Lukas
What we have here, is an MTHFR situation. In this episode we'll talk about: The three scenarios when taking the right kind of folate feels yucky Wh...
What to Eat for MTHFR Mutants. More Importantly, What NOT to Eat.
30 Aug 2020
Contributed by Lukas
We've talked about the difference between natural folate and synthetic folic acid, but what does that mean in terms of eating for your MTHFR mutation?...
Psst... There are Different Types of Folate. Which is Best For You?
23 Aug 2020
Contributed by Lukas
The term "folate" is incredibly confusing because for whatever reason, the term is used interchangeably with "folic acid," which is an entirely differ...
This Vitamin Could Be Hurting You. Not Just For MTHFR!
16 Aug 2020
Contributed by Lukas
There is a vitamin that is helpful in normal doses, but toxic in high doses. It is added to your food, energy drinks, and of course, your multivitamin...
MTHFR and Neurotransmitters - An Unholy Marriage
09 Aug 2020
Contributed by Lukas
Why does MTHFR have so many mental and psychological effects? This is it! Find out: What MTHFR has to do with neurotransmitter formation What BH4 i...
MTHFR Is In Bed With Estrogen. Now What?
02 Aug 2020
Contributed by Lukas
MTHFR doesn't seem obviously linked to hormone balance, so what is happening here? Listen to find out: Why in the world MTHFR gets its sticky finger...
Methylation, Detoxification, and the Glamorous MTHFR Lifestyle.
26 Jul 2020
Contributed by Lukas
What is the glamorous MTHFR lifestyle? It's maybe a bit less glamorous and more just... lifestyle. In this episode we'll talk about: What does...
Why Is Methylation Important? Gene Regulation.
19 Jul 2020
Contributed by Lukas
In this episode we'll cover: The four major reasons why methylation matters The mutant Mickey Mouse of methylation The big reasons why we need to...
Who Should Care About MTHFR Mutation?
12 Jul 2020
Contributed by Lukas
The internet seems to think that everyone should, but it simply isn't true. In this episode we'll cover: The four circumstances in which MTHFR mutat...
MTHFR Testing and Results - What Does This Mean?
05 Jul 2020
Contributed by Lukas
Testing isn't for everyone. In this episode, you'll learn: When your doctor might test. Who really should test Who really shouldn't How to test...
Health Problems Linked to MTHFR Mutations
28 Jun 2020
Contributed by Lukas
This week we'll talk about the health issues associated with MTHFR mutations (or polymorphisms). These include: Midline abnormalities Cancer Card...
What is MTHFR in the simplest terms possible? It's a magic chair.
21 Jun 2020
Contributed by Lukas
MTHFR research on the internet can lead to a back hole of confusion, so let's demystify it with the "magic chair" analogy. What is the MTHFR magic c...
Trailer and bonus P.S.A. from a 4-year-old.
02 Jun 2020
Contributed by Lukas
To Health With That! is a great way to learn a lot about a big health topic in small, bite-sized pieces. Season One will cover the ins and outs of the...