Dr. Gabrielle Lyon

speaker

20,614 appearances 52 recordings 13 series first heard Nov 2024 last heard 2d ago

Dr. Gabrielle Lyon’s voice in public audio — every appearance, attributed to the second.

Trend

recordings per month · last 12 months

Recordings per month over the last 12 months — 46 in all, peaking in Sep 2026 with 9.

Appearances

newest first · ▶ plays the moment

The Dr. Gabrielle Lyon Show · Nobody Told You This About Creatine · 27 Aug 2026 podcast

Sleep deprived people are a newer and smaller story, but I think we're going to start to see more and more research. podcast-host

A single large dose in the range of 0.35 grams per kilogram, which for a 150 pound person is a whopping 24 grams. podcast-host

And that partially reversed declines in processing speed during 21 hours without sleep. podcast-host

Sounds podcast-host

like they have a newborn. podcast-host

And with brain energy, metabolites improving on imaging, which is pretty extraordinary. podcast-host

The evidence base is there, but it's still very early. podcast-host

What about people with depression? podcast-host

They might benefit from creatine as an add on to standard SSRIs. podcast-host

Individual trials show large effect sizes through a meta-analysis, though found only a small to moderate benefit overall. podcast-host

And the evidence quality is low. podcast-host

So hold that thought because there's an important caveat in the contraindications, which there are not many. podcast-host

Aging brains. podcast-host

More broadly, five of six studies in adults over 55 found a positive relationship between creatine and cognition, particularly in memory and attention. podcast-host

And now we've been using creatine in soldiers for a long time. podcast-host

And traumatic brain injury, creatine has shown promise in pediatric TBI outcomes and preclinical models that support neuroprotection across Parkinson's, Huntington's, and ALS. podcast-host

Now, this is early and mechanistic, but I did want to flag the humility here that the direction is certainly. podcast-host

Worth our attention. podcast-host

Now, and most importantly, really the safety profile, because this is where fear mongering and misinformation lives. podcast-host

Now, at three to five grams a day, this is backed by hundreds of peer-reviewed publications. podcast-host

Showing 3281–3300 of 20,614 · page 165 of 1031