JJ Virgin
speaker
1,112 appearances
7 recordings
5 series
first heard Nov 2024
last heard 1 Mar
JJ Virgin’s voice in public audio — every appearance, attributed to the second.
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recordings per month · last 12 monthsRecordings per month over the last 12 months — 2 in all, peaking in Mar 2026 with 1.
Appearances
So we can start to do the things to help your body produce it, right? Like improve your L cells, things like acromantia. You've probably heard of that. Things that help slow down the breakdown of this. There's this DPP-4 enzyme that breaks it down. So we could slow it down. We can help with production of it. However, some of these people may never have it come back online.
It doesn't need to be expensive. When you look at the compounded versions, it could be $50 a month. For a lot of these people, they're on polypharmacy. They're spending more on their high blood pressure, their lipid-lowering drugs. And if they went on this, and they eat less, right? So if they went on these things, low dose, a microdose is usually about a fifth of the dose.
You may have to go up to the starting dose, but then you could back down. But here's what needs to happen. If it could be the case that if you wanted to use one of these, you had to go in and get your body composition tested and be consistent with checking your body composition because it doesn't cause muscle loss. Caloric restriction causes muscle loss.
Any diet poorly designed causes a 20 to 30% loss in skeletal muscle. That is the diet. It's not the drug. The drug actually doesn't cause muscle loss. It doesn't. In fact, you can gain muscle on the drug. So that's BS. But that's the thing that a lot of people are talking about, right? Not true. It's the diet. It's the diet.
So if you are any diet that does not have optimal protein and you're not doing resistance training, you'll lose skeletal muscle if you're doing caloric restriction. That's the way that works. So if you are...
eating correctly getting that protein and maybe supplementing with essential amino acids if you're too low in protein if you're doing your resistance training which first you just start with getting the person to move because a lot of these people are the average person's walking 3 000 steps a day 3 000 so really if we just got them to walk to 8 000 if we started to get some air squats in you know we just get them moving and you know working with people who are morbidly obese
We oftentimes have to have an air squat over, say, a couch arm because it just hurts so much. So we've got to get the inflammation down. Then you start to improve the diet, right? You get them moving more. You get them sleeping. They might need to do some sleep therapy because a lot of times when you're obese, you don't sleep well. Then you start and you can taper it.
Will they have to be on it for life? They might have to cycle it for life, low dose. But I contend that that would be better than living a life of obesity on medications.
What are they taking it for? Are they taking it because they had issues? Vanity reasons. Vanity reasons. There's other I mean, yes, you could use it for vanity reasons. However, you could also use it for inflammation. You could use it for APOB, like my husband's on a teensy cycling dose. And these cycling doses are not meant to take your appetite away, right?
It's purely to lower his APOB that was chronically elevated. We tried everything, couldn't get it to go. Same with my son is using it for his brain. So you can use low doses of these, not for body composition, but for inflammation, for insulin sensitizing, for neuroregeneration, for microvascular dilation. There's other things they do. And there's a whole host.
Like if you go to Consensus and chat GPT and plug in benefits of GLP-1 agonists, it's kind of mind-blowing overwhelming. That's a PubMed, you know, thing. So... But what about the side effects? Well, the side effects when you're low dosing are not an issue.
Yeah, like you should, they start, the dose they start people with is ridiculous. Like it's way higher than it should ever be.
So let's say I am not a physician. I don't play one on podcasts. If I were working with someone who I could work with a physician who would get compounded pharmacy, you know, triseptide or semaglutide, I would start with about a fifth of the starting dose. And I would start super low with that in combination with they have to track their food.
They have to make sure they're getting in their protein, one gram per pound of target body weight. And then we're going to start to move. And then we see how they do. And then we get them, you know, we'll see if we have to raise it or not. And then if we do have to raise it, you just continue to do all the other stuff. So hopefully you can start to take it down.
And then cycling might be once every two weeks, once every three weeks, once every month.
I take a teensy bit of it. Now, here's what's interesting. I tracked everything with this because I have a weird autoimmune thing that every once in a while... Remember I talked about how my weight went up?
This weird little autoimmune thing that every once in a while will trigger. And I'm like, what the heck is that? And so... I was 144 pounds and like 11, 12 percent. I think it was 11 percent body fat when I did it. And I went on and the person who initially put me on it put me on a starting dose. It was too much. It was way too much. And so that dropped me like I like. And it was funny.
Here's what's weird. I was actually tracking my calories and I didn't change what I was doing or eating by more than 200 calories. But I went down to 138. And so I popped the dose way down and started cycling it. So basically a fifth of the dose once or twice a month, right? And came back up to my normal weight, normal body fat. And so it's one you just have to watch.
But I use the teensiest dose every once in a while. Right. All the autoimmunity stuff at bay because there's good research on that.
Oh, is this like intermittent faster, do you mean? Well, you know, fasting's kind of such a tough word because what's it really mean? It could mean anything from normal eating, like stop eating three hours before bed, eat about an hour or two after waking up in the morning. That's like to me what we should be doing. Get that, you know, 10 to 12 hour window.
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