Mike Israetel
speaker
1,094 appearances
5 recordings
5 series
first heard Dec 2024
last heard May 2025
Mike Israetel’s voice in public audio — every appearance, attributed to the second.
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Appearances
Mind Pump: Raw Fitness Truth · 2595: Mike Israetel Unplugged (Explicit Content) · 12 May 2025
podcast
And all of the other related compounds exist. And that is because muscle growth is two things in the natural evolved environment. At some point, totally fucking useless. Cause like take Ronnie Coleman in his prime. What exactly is the adaptive value of being 287 pounds of 3% body fat? Like, I mean, you're not really any better at hunting.
You're not going to be picking fucking pear trees any better to gather the shit. You don't weave baskets any better. So in a typical human evolved environment, it's fucking pointless. And the second thing is it is metabolically insanely expensive to build muscle and to maintain muscle. And so your body evolved in an intermittent starvation environment.
Like sometimes there was food and sometimes the fucking buffalo herd didn't zig by your village and half of you fucking starve to death. And so the body is incredibly, incredibly efficient with its calories such that you guys know this, I'm sure from personal experience, when you work out a lot, you get really tired and you sit around a lot more and your body doesn't even let you lose more weight.
There's a reason it's really hard to diet off a bunch of weight because your body's just not interested in the shit. It's really economical. if we uncork the muscle growth process in the wild, we start to divert so many resources to muscle growth that we just don't have much food. Then you're fucking pretty jacked. You're pretty shredded and you're dead on the side of the road.
Cause you couldn't fucking like your liver that can't fucking get enough calories to operate. The good news is we have capitalism fucking grocery stores and we're all by, by, by historical standards, hyper, hyper fucking rich. And so because we have infinity food now, we, yeah, there may be no functional big downsides.
Now, of course, there's going to be some adverse effects like that with every drug. There's going to be some people that just don't take to the shit and they have some bad downsides. But on the whole, you're likely to see a side effect profile with these drugs that you do with semaglutide and terzapatide. Like, yeah, there's some shit. And if you take it wrong, it fucks you up a little bit.
But on average, almost everyone tolerates it really well. And it's probably healthier to take the shit than not take the shit. One really cool thing about the GLP-1s and the GIPs is More and more research shows that regardless of if you lose weight with them or not, they have like 10 incredibly beneficial overall health and metabolic effects.
These are fucking wonder drugs, you guys, to be used responsibly. And they can have downsides. But if you figure out the dosing and figure out your diet, for most people, these drugs are awesome. So myostatin inhibitor drugs, the activant inhibitor drugs, and I'm sure the fucking eight generations of even better versions of those that are coming up afterwards.
It's going to be one of those things of, like, what's the downside of Viagra? Like, you see slightly different shades of blue, and your head kind of hurts, and your nose is puffy, which is a problem, because if you're doing cunnilingus, how the fuck are you supposed to breathe through your nose and mouth at the same fucking time? This is the only problem.
Otherwise, your dick just gets engorged, and you're out there slaying, fellas. So, you know what I'm saying? Like, talk some shit about Cialis. I'm not going to be here for it. It's a fucking wonder drug. We should have everyone on.
It holds a lot of water. It's not fucking magic, but it also depends on how extreme it is. If you have a client who's 230 pounds and they lose 15 pounds, you don't need to do crazy protocols to get their metabolism backfiring. It's probably better than it's ever been. If you have a competitor who's gone down to 4% body fat, you can't even reverse diet them. You need to bulk them out of that.
One of the big myths with reverse dieting when it came up was People realized it worked pretty well. And so a lot of competitors were like, oh my God, if I reverse diet out of my show, I can stay 5% body fat and gain back all these benefits. Like, no, you just can't stay at 5%. You got to bulk your way the fuck back up out of that. But if you are adding lots of muscle to your body over time,
And if you are careful to not crash your metabolism during a diet or you slowly weave back in some junk foods and just increase the amount of healthy food, you're going to get a lot of really, really big advantages that are way, way better than the kind of quote-unquote traditional method of dieting, which is don't weight train, don't put on muscle, starve yourself for a while.
You guys remember shit like the cabbage soup diet and dumb shit like that, like shit housewives would do? They would just lose a bunch of muscle, lose a bunch of fat, and then just get right back to their normal eating habits. They would be really hungry, really tired. Metabolism is slower. They would regain all their weight and then some.
And then they would be a fall prey to marketers for their next fucking diet. If you properly reverse diet out of that and combine that with weight training, about two or three months after your last diet, you're down 15 pounds. You feel amazing. You look amazing. And you can totally sustain it. And if you want another run at it, you can do another bit of weight loss and kind of keep going.
That long-term periodized approach to weight loss and management, including dieting, Using resistance training to build muscle? I mean, it is 100% the fucking correct answer. Does everyone do it now? No. Are more people doing it than ever? Yes, 100%.
Yeah. There's like one answer that probably explains 80% of the variance. It's not very nice, but it's probably true. Uh, she was not eating 1400 calories. The way that people report their diet is typically like how you tell your dentist, you guys go to the dentist, right? Clearly you're all handsome men with great teeth. Um, The dentist is like, you've been brushing and flossing?
You fucking haven't. You've just been, you know what I'm saying? Like, is eating pussy a way of flossing? Yes. Then no. But, you know, like, you know, we're not great about it. Like, technically, the American Dental Association, I think, says, like, ideally, you should brush and floss after every meal. Fellas, what? Who the fuck does that? You don't do that.
But when your dentist asks you, you know, have you been brushing and flossing? A lot of us were like, yes, yes, ma'am. And yeah, like, that's just how it goes. So when you seek out the help of a trainer, there's this kind of like, it's like going to a religious figure, like a pastor. And he's like, how have you been? And you're like, great, really trying to live a Christian lifestyle.
And it's like, no, you haven't, dude. You're basically a professional gambler at this point. Yeah. But when you talk to Pastor John, you're going to tell him a nice story. And so when people go to trainers, there's that halo effect where they want to present their best case. I was working for a fitness company with my co-founder of RP, Nick Shaw.
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