108: 5th WSC – Sepsis Epidemiology and Clinical Data
episode
5th World Sepsis Congress: Sepsis Research and Innovations
1h 18m
8 chapters
transcribed 17 days ago
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What are the global statistics on sepsis mortality and incidence?
Hello and thank you for tuning in today. You're listening to session two of the Fifth World Sepsis Congress, titled Sepsis Epidemiology and Clinical Data. Over the next 75 minutes, you'll hear from five outstanding speakers sharing their expertise on this critical topic. The session is moderated exquisitely by Eleanor Nadinobi, president of the Medical Women's International Association. Eleanor, over to you.
I am Doctor Eleanor Madinovi President of the Medical Women's International Association. An association globally of female medical practitioners. The Medical Women's International Association. It's a pioneer partner. Of the global sepsis alliance. I am deeply honored to be your moderator. For this session Which is session two. For the twenty twenty five and fifth edition of the World Sepsis Congress. Under the title Sepsis, Epidemiology and Clinical Data. We all know. That data is the new gold. We do have sobering statistics that sepsis is responsible for one in every five deaths worldwide. And affecting nearly fifty million people each year. So we have A wonderful lineup of Erudite speakers to speak on this very important topic.
And to you. Our cherished audience We would like to hear from you for this. It's an interactive time together. And we do want it to be as interactive as possible. I do have some housekeeping rules. We would love to hear from you. And please use the QA function for your comments. And if you have a specific question, please type the letter Q. Followed by home long. That way We'll be able to see your questions clearly and appropriately address them. So let's move right into the sessions. Our very first speaker for today. Is Mosan Nagavi, who is a professor of health metrics sciences and director of subnational burden of disease estimation at the Institute for Health Metrics and Evaluation at the University of Washington.
In his role, Moson leads the institute's work on subnational analysis of disease burden Working closely with international collaborators and country governments, including Projects in Brazil, Russia, Iran, China, and Ethiopia. In 2015, Mosan was named one of the world's most influential scientific minds by Thomson Reuters. This accolade and award was also repeated in 2016. So without Further ado. It is my pleasure. to ask Professor Morsen to make his presentation. Over to you, Professor.
Thank you so much. Thank you, Eleanor. I will talk about because I have fifteen minutes I have to talk very fast. I will talk about global burden of sepsis and AMR. I try to explain how we calculate elite And what is the result and why we calculate sepsis? And what is the benefit of the sepsis for the uh public health and for the uh improving knowledge. Okay. Let's talk about two any two any one. In twenty twenty one, sixty six million people. died globally six sixty six point two million It was the year that we had covet. From D sixty six point twenty one point four die by sepsis and as you see that a definition of definition of sepsis for us is exactly the same as definition that you are using. Acute life-threatening organ dysfunction due to the dysregulation host of response to the infections.
And then based on the method that we published in the Lancet twenty seventeen and we submitted again a new version in the Lancet that will come soon hopefully. Uh our method is based on the calculation of the fraction of the sepsis in the multiple causes of deaths, and then apply this fraction after the modeling process to the uh all cause mortality and well and calculate number of the deaths due to the sepsis. But Just we do not calculate sepsis, also we calculate infectious syndrome. Infectious syndrome is the causes that is breach between underlying cause and the sepsis. For example How is it possible that somebody with a or we'll have UTI. Den we calculat uh boths sepsis and infectious synters. Then Based on the number that we have, uh in twenty twenty one as you see, we have uh twenty one million deaths due to the sepsis with the one hundred and sixty six million
incidence. The reason that is different with our paper because in the incidence part we included implicit sepsis.
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Chapters
8 chapters
1
What are the global statistics on sepsis mortality and incidence?
0:01–8:18
2
How does Professor Mohsen Naghavi calculate global sepsis burden using sub‑national disease modeling?
8:18–17:16
3
What trends are observed in sepsis deaths by age and region from 1990 to 2021?
17:16–28:35
4
How do ICD coding practices affect sepsis epidemiology estimates?
28:35–38:58
5
What did the Baseline African Sepsis Incidence Study (BASIS) reveal about sepsis patterns in sub‑Saharan Africa?
38:58–49:19
6
How does the Latin American Sepsis data highlight gaps in ICU capacity and patient transfers?
49:19–1:00:31
7
What does the Asia‑Pacific data show about sepsis care outside of intensive care units?
1:00:31–1:09:47
8
What are the key take‑aways and future research priorities identified by the panel?
1:09:47–1:18:12
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