BDNF Superpowers Through MDMA and Ketamine | Dr. Dave Rabin : 1486
episode
The Human Upgrade: Biohacking for Longevity & Performance
1h 10m
1 speaker
8 chapters
transcribed 1 month ago
Transcript
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Transcript generated automatically by AI and may contain errors.
What is treatment‑resistant depression and why do half of patients fail standard meds?
Trauma is now repairable and reversible down to the epigenet code. So there's hope for everyone. In the first 30 minutes of every day, you look at your smartphone for and you've taken in as much information as the average human being took in in a week of being alive in the 1950s. People are getting prescribed medicine for life, and people are starting to get tons of terrible side effects from the medicines, and they're just not getting better in this. Psychedelic medicines are some of the most powerful tools we've ever had access to in the history of psychiatry. Cetamine is the best start. starting place for anyone if you're starting out in this area. It's the easiest, most gentle. It only lasts 60 minutes, and you can do, you know, a full course of therapy legally and accessible in basically
Every state. You mentioned MVMA, you mentioned psilocybin, and you mentioned ketamine. So how would someone know which is the right one for them? You're listening to the human upgrade with Dave Asprey. There's a youth molecule in all your cells that you're losing every year. It's NAD plus. It repairs your DNA and supports your mitochondria, helps your body convert food into usable energy, it keeps your metabolism running, it helps you regulate inflammation. And if you want to live a long time, you're gonna need it. But by the time you reach your 40s, your NAD plus levels are about half what they were when you were age 20. That's if you're even healthy when you're 20. Good news is that you can take supplements that raise your NAD levels.
Plus levels. Bad news is that a lot of them don't work. And for something as important as my NAD plus levels, I don't want to hope a supplement works. I want to know it does. Some supplements have nothing supporting their claims. Others do a little better with studies on just ingredients in their product. But the gold standard is when a company runs a clinical study on the product itself. Did you know out of 90,000 supplement products, only about a hundred are clinically proven? Qualia NAD Plus is one of those. In multiple double blind placebo controlled studies, it increased NAD plus levels by 67%. So if you want to take the guesswork out of maintaining high NAD plus levels as you age, go to qualialife.com slash Dave NAD and they'll give you 15% off at checkout.
They also have a hundred-day money-back guarantee, so what do you have to lose? That's qualialife.com slash DaveNAD. You're losing hair on your head and collagen in your skin right now, even though you probably can't see it yet. And that process speeds up as you age and it doesn't reverse on its own. But you can intervene at the cellular level. Studies show that specific wavelengths of red and near infrared light will stimulate your hair follicles, and that does support collagen production. IRestore has been making red light therapy devices that actually work for over two decades. And with their some Savings event, it's the perfect time to upgrade your hair and skincare. The iRestore Elite is their most advanced laser hair growth system using 300 lasers and 200 LEDs, which helps you regrow thicker, healthier hair in about three months.
And it is really easy to use. You can wear it while you're working, while you're reading, or unwinding at night. And the Illumina face mask: 360 medical grade LEDs. can turn red, infrared, or even blue light at the same time to target all of your different skin concerns. Just ten minutes, a few times a week gives you brighter, smoother, and healthier looking skin. I've been using the Iberstore Elite and the Illumina face mask while I work at home, but not on video. And they fit into my normal routine with no extra time cost. I really like it because I don't lose any time when I use it. iRestore is so confident you'll love their products that they give you a 12-month money-back guarantee. That's because it actually works.
You will see more hair. iRestore is kicking off their summer savings event with some huge discounts on their red light therapy devices. You can save on customer favorites like the iRestore Elite helmet and the Illumina face mask.
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Chapters
8 chapters
1
What is treatment‑resistant depression and why do half of patients fail standard meds?
0:00–8:55
2
Why is ketamine considered the safest and most accessible entry point for psychedelic therapy?
8:55–17:01
3
How does MDMA trigger a BDNF‑dependent pathway that repairs fear extinction in the amygdala?
17:01–26:13
4
What epigenetic changes does MDMA‑assisted therapy make to the cortisol‑receptor gene?
26:13–35:48
5
How do SSRIs and SNRIs block the insula‑mediated brain states needed for emotional healing?
35:48–44:01
6
Why does everyday smartphone use put the nervous system into a chronic fear state?
44:01–53:04
7
How can the vagus nerve be activated to shift the body from a stress‑to‑safety state?
53:04–1:01:56
8
Why did the FDA reject MDMA therapy despite an 88% response rate in trials?
1:01:56–1:10:05
Speakers
1 identifiedMore from The Human Upgrade: Biohacking for Longevity & Performance
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