Brain Fog, Memory Loss, and Alzheimer's Prevention | Dr. Majid Fotuhi : 1482
episode
The Human Upgrade: Biohacking for Longevity & Performance
1h 27m
1 speaker
8 chapters
transcribed 1 month ago
Transcript
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Transcript generated automatically by AI and may contain errors.
Why is my brain shrinking and how can I stop it?
This is Majid Fattouhi, MD, PhD, Johns Hopkins, Harvard trained. 36 years of experience teaching and writing and studying about brain.
A lot of people think brain issues are things that are directly related to your brain. So if you have numbness in your toes, swelling in your ankles, back pain, if you're taking medications, urinary frequencies, if your shoulder hurts, if you have headaches, if you have neck pain, there's so many things that can affect the brain. We know that... is a major risk factor for Alzheimer's disease. We also know that people who have have small epicampus. So the brain does shrink.
You're listening to The Human Upgrade with Dave Asprey. Thank you.
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If you've been listening to the show for a while, you know that the most important thing isn't longevity, it's having a brain that works. Because what kind of a nightmare would it be to live like me to at least 180, but the entire time to not know your own name and to put your car keys in the refrigerator and all the other things that we've seen people do, in fact, it's why some people are afraid of longevity, is they have this picture of being weak and even worse, being stupid. And in my path, I started out being all those things. Weak and stupid. Actually, that's all babies come to think of it. But that's not what I'm talking about. Because I felt my brain failing when I was going to Wharton Business School when my career in Silicon Valley was taking off.
I was... dealing with profound chronic fatigue, fibromyalgia, and my brain just didn't work. So I started out studying nootropics. This was, I don't want to say how many years ago, 25 years ago, something like that. And then I really got into neuroscience and neurofeedback and all these different things because I wanted my brain to work. And soon I figured out, oh man, I guess I'm going to have to get my biology to work. Thank goodness people in their 80s are teaching me how they're getting younger because it's turning my brain back on. So I don't think you can separate...
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Chapters
8 chapters
1
Why is my brain shrinking and how can I stop it?
0:00–12:04
2
What are the five pillars of brain health and why do they matter?
12:04–22:49
3
How does exercise grow the hippocampus and improve memory?
22:49–33:32
4
Why are optimal B12 and folate levels critical for brain function?
33:32–45:53
5
How does the APOE4 gene affect Alzheimer’s risk and can exercise erase it?
45:53–56:52
6
What do psychedelics like psilocybin and ketamine do for the brain?
56:52–1:06:55
7
Do GLP‑1 drugs protect the brain or make you “stupid”?
1:06:55–1:17:55
8
Why is VO₂ max the best single predictor of brain aging?
1:17:55–1:27:52
Speakers
1 identifiedMore from The Human Upgrade: Biohacking for Longevity & Performance
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