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くつ王レディオ

Health & Fitness

Episodes

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敗血症患者の侵襲性カンジダ感染症、βDグルカン ガイド治療は有効か?CandiSep試験から見えた意外な真実 Intensive Care Med

04 Oct 2025

Contributed by Lukas

(1→3)-β-D-Glucan-guided antifungal therapy in adults with sepsis: the CandiSep randomized clinical trialCitationIntensive Care Medicine, 2022; 48: ...

レビュー:免疫不全とデング熱:意外な関係?合併症・重症化・移植臓器への影響を徹底究明 IJID

03 Oct 2025

Contributed by Lukas

Dengue fever in immunocompromised patients: A systematic review and meta-analysisCitationInternational Journal of Infectious Diseases, 2024; 149: 1072...

選択的消化管除染(SDD)が侵襲的機械換気を受ける成人の入院死亡率および臨床アウトカムに及ぼす影響 JAMA

03 Oct 2025

Contributed by Lukas

Effect of Selective Decontamination of the Digestive Tract on Hospital Mortality Among Adults Receiving Invasive Mechanical Ventilation: A Randomized ...

再発性UTI予防に新常識?ALTAR試験が示す抗生物質以外の選択肢、メテナミンの可能性と耐性菌問題の深層 BMJ

03 Oct 2025

Contributed by Lukas

Alternative to prophylactic antibiotics for the treatment of recurrent urinary tract infections in women: multicentre, open label, randomised, non-inf...

レビュー:野兎病の30年データ 最恐の感染症に効く治療薬、バイオテロへの備えとシプロフロキサシンの可能性 CID

02 Oct 2025

Contributed by Lukas

Systematic Review: Clinical Features, Antimicrobial Treatment, and Outcomes of Human Tularemia, 1993–2023CitationClinical Infectious Diseases, 2024;...

結腸・直腸手術後の感染リスクを40_削減?経口抗菌薬の効果と「MBP」の複雑な関係を深掘り! BMJ

02 Oct 2025

Contributed by Lukas

Effect of oral antimicrobial prophylaxis on surgical site infection after elective colorectal surgery: multicentre, randomised, double blind, placebo ...

男性UTIの治療期間は7日間で十分?常識を覆すJAMA論文を徹底解説! JAMA

02 Oct 2025

Contributed by Lukas

Effect of 7 vs 14 Days of Antibiotic Therapy on Resolution of Symptoms Among Afebrile Men With Urinary Tract Infection: A Randomized Clinical TrialCit...

レビュー:マラリア最前線 巧妙な敵と終わらない追いかけっこ〜進化する脅威と希望の光〜 NEJM

01 Oct 2025

Contributed by Lukas

MalariaCitationNew England Journal of Medicine, 2025; 392(13): 1320–1333概要本総説は、マラリアの世界的な現状と課題、診断・治...

SSI予防の常識を覆す!低コストで効果絶大な手袋・器具交換の真実〜世界を変えるChEETAh試験〜 Lancet

01 Oct 2025

Contributed by Lukas

Routine sterile glove and instrument change at the time of abdominal wound closure to prevent surgical site infection (ChEETAh): a pragmatic, cluster-...

侵襲性アスペルギルス症治療の標準を変えるか?ポサコナゾールとボリコナゾールの非劣性・安全性比較を徹底解説 Lancet

01 Oct 2025

Contributed by Lukas

Posaconazole versus voriconazole for primary treatment of invasive aspergillosis: a phase 3, randomised, controlled, non-inferiority trialCitationThe ...

レビュー:薬剤耐性が深刻化!性感染症マイコプラズマ・ジェニタリウム(MG)の「静かなる流行」に迫る Infectious Disease Clinics of North America

30 Sep 2025

Contributed by Lukas

Update in Epidemiology and Management of Mycoplasma genitalium InfectionsCitationInfectious Disease Clinics of North America, 2023; 37(1): 133–151概...

糖尿病性足感染症とMRSA:鼻腔スクリーニングで「ない」を知る!抗菌薬適正使用の新常識 Antimicrobial Agents and Chemotherapy

30 Sep 2025

Contributed by Lukas

Utility of Methicillin-Resistant Staphylococcus aureus Nares Screening for Patients with a Diabetic Foot InfectionCitationAntimicrobial Agents and Che...

腎盂腎炎治療の盲点?古くて新しいアミノグリコシド系の再評価と耐性菌への可能性 J Antimicrob Chemother

30 Sep 2025

Contributed by Lukas

Effectiveness and safety of an institutional aminoglycoside-based regimen as empirical treatment of patients with pyelonephritisCitationJournal of Ant...

レビュー:エムポックス新潮流 クレードIbの脅威とパンデミック予防への問い EID

29 Sep 2025

Contributed by Lukas

Emergence of Clade Ib Monkeypox Virus — Current State of EvidenceCitationEmerging Infectious Diseases, 2025; 31(8): 1516–1525概要本レビュー...

尿路感染による菌血症:経口βラクタム薬はステップダウン治療の選択肢となるか? JAMA Netw Open

29 Sep 2025

Contributed by Lukas

Oral β-Lactam Antibiotics vs Fluoroquinolones or Trimethoprim-Sulfamethoxazole for Definitive Treatment of Enterobacterales Bacteremia From a Urine S...

「メロペネム_vs_ピペラシリンタゾバクタム:厄介なAmpC産生菌感染症治療の課題と未来〜MERINO-2試験から紐解く複雑な真実〜 OFID

29 Sep 2025

Contributed by Lukas

Meropenem Versus Piperacillin-Tazobactam for Definitive Treatment of Bloodstream Infections Caused by AmpC β-Lactamase–Producing Enterobacter spp, ...

レビュー:致死率の高い感染症「HCID(High‑Consequence Infectious Disease)」 未知なる脅威への備えと対応戦略 EID

28 Sep 2025

Contributed by Lukas

Preparedness and Response Considerations for High-Consequence Infectious DiseaseCitationEmerging Infectious Diseases, 2025; 31(8): 1507–1515概要本...

MERINO試験再検証:抗菌薬感受性検査の「罠」と耐性遺伝子が招く治療格差〜ピペラシリン_タゾバクタム_vs_メロペネムの真実〜 CID

28 Sep 2025

Contributed by Lukas

Association Between Minimum Inhibitory Concentration, Beta-lactamase Genes, and Mortality for Patients Treated With Piperacillin/Tazobactam or Meropen...

MBL産生菌感染症の切り札?最難関の細菌に挑む新治療戦略と未来への課題 CID

28 Sep 2025

Contributed by Lukas

Efficacy of Ceftazidime-avibactam Plus Aztreonam in Patients With Bloodstream Infections Caused by Metallo-β-lactamase–Producing EnterobacteralesCi...

腎移植後の「無症候性細菌尿」:BiRT研究が覆す常識と薬剤耐性菌のリスク  Clinical Microbiology and Infection

27 Sep 2025

Contributed by Lukas

Antibiotics versus no therapy in kidney transplant recipients with asymptomatic bacteriuria (BiRT): a pragmatic, multicentre, randomized, controlled t...

レビュー:パンデミックの火種「スピルオーバー」を初期段階で防ぐ鍵 ワンヘルス調査の重要性 EID

27 Sep 2025

Contributed by Lukas

A Roadmap of Primary Pandemic Prevention Through Spillover InvestigationCitationEmerging Infectious Diseases, 2025; 31(8): 1501–1506要約COVID-19パ...

手術後の抗菌薬、本当に必要?最新エビデンスが示す「術前・術中予防」の決定的な重要性 Lancet ID

27 Sep 2025

Contributed by Lukas

Effect of postoperative continuation of antibiotic prophylaxis on the incidence of surgical site infection: a systematic review and meta-analysisCitat...

レビュー:感染性心内膜炎治療の常識が変わる!?飲み薬への切り替えは安全か? JAMA

26 Sep 2025

Contributed by Lukas

Evaluation of a Paradigm Shift From Intravenous Antibiotics to Oral Step-Down Therapy for the Treatment of Infective Endocarditis: A Narrative ReviewC...

結腸手術の常識が変わる!?術前1日の抗菌薬で感染リスク半減〜MBPなしの新常識〜 Lancet Gastroenterology & Hepatology

26 Sep 2025

Contributed by Lukas

Preoperative oral antibiotics and surgical-site infections in colon surgery (ORALEV): a multicentre, single-blind, pragmatic, randomised controlled tr...

尿路感染症のステップダウン療法:ホスホマイシンはシプロフロキサシンに劣らない代替薬となるか?~FORECAST試験から治療のゴールを問い直す~ CID

26 Sep 2025

Contributed by Lukas

Fosfomycin vs Ciprofloxacin as Oral Step-Down Treatment for Escherichia coli Febrile Urinary Tract Infections in Women: A Randomized, Placebo-Controll...

菌血症の抗菌薬治療:14日は長すぎる?JAMA論文から読み解く最適期間と個別化医療の可能性 JAMA

25 Sep 2025

Contributed by Lukas

Effect of C-Reactive Protein–Guided Antibiotic Treatment Duration, 7-Day Treatment, or 14-Day Treatment on 30-Day Clinical Failure Rate in Patients ...

敗血症抗菌薬、ナッジで減らせる?オプトアウト戦略の光と影~DETOURS試験が示す医療現場のリアル~ CID

25 Sep 2025

Contributed by Lukas

Evaluation of an Opt-Out Protocol for Antibiotic De-Escalation in Patients With Suspected Sepsis: A Multicenter, Randomized, Controlled TrialCitationC...

レビュー:食品の微生物腐敗―その影響、原因微生物、制御戦略 Nature Reviews Microbiology

25 Sep 2025

Contributed by Lukas

Microbial food spoilage: impact, causative agents and control strategiesCitationNature Reviews Microbiology volume 22, pages528–542 (2024)論文の...

納豆菌が血流に!健康食品の代表「納豆」が引き起こす重篤な菌血症の実態と驚愕の致死率16%:遺伝子解析が明かした臨床的意義 OFID

24 Sep 2025

Contributed by Lukas

元の論文:The majority of Bacillus subtilis strains isolated from blood cultures were derived from traditional Japanese fermented soybeans Natto:...

肺炎治療の隠れた一手?古くて新しい抗生物質ドキシサイクリンの可能性と課題 CID

24 Sep 2025

Contributed by Lukas

Efficacy of Doxycycline for Mild-to-Moderate Community-Acquired Pneumonia in Adults: A Systematic Review and Meta-Analysis of Randomized Controlled Tr...

トキソプラズマ脳炎治療の常識が変わる?高騰薬の代替は同効果で安全性が高いのか CID

24 Sep 2025

Contributed by Lukas

Revisiting the Evidence Base for Modern-Day Practice of the Treatment of Toxoplasmic Encephalitis: A Systematic Review and Meta-AnalysisCitationClinic...

レビュー:創傷マイクロバイオームが創傷治癒や感染に及ぼす影響 Nature Reviews Microbiology

24 Sep 2025

Contributed by Lukas

The wound microbiota: microbial mechanisms of impaired wound healing and infectionCitationNature Reviews Microbiology, vol. 22, pp. 507–521 (202...

人工呼吸器関連肺炎に挑む新薬テジゾリド:標準薬リネゾリドとの比較から見えた生存率と治癒率の複雑な関係性 CID

23 Sep 2025

Contributed by Lukas

A Phase 3, Randomized, Double-Blind Study Comparing Tedizolid Phosphate and Linezolid for Treatment of Ventilated Gram-Positive Hospital-Acquired or V...

移植後の難治性CMV感染症に新薬が光を灯す:マリバビル「SOLSTICE試験」が示す治療の未来と課題 CID

23 Sep 2025

Contributed by Lukas

Maribavir for Refractory Cytomegalovirus Infections With or Without Resistance Post-Transplant: Results From a Phase 3 Randomized Clinical TrialCitati...

レビュー:デング制御における Wolbachia 利用とウイルス適応リスク Journal of Virology

23 Sep 2025

Contributed by Lukas

Using Wolbachia to Eliminate Dengue: Will the Virus Fight Back?CitationJ Virol, 95(13):e02203‑20 (2021)論文の要約本レビュー論文は、デ...

糖尿病性足骨髄炎の常識を覆す?3週間抗菌薬治療の可能性と今後の展望 CID

22 Sep 2025

Contributed by Lukas

Three Weeks Versus Six Weeks of Antibiotic Therapy for Diabetic Foot Osteomyelitis: A Prospective, Randomized, Noninferiority Pilot TrialCitationClini...

MSSA血流感染症の治療戦略を問う:ダプトマイシン併用は本当に有効か?DASH試験が示す意外な真実 CID

22 Sep 2025

Contributed by Lukas

Adjunctive Daptomycin in the Treatment of Methicillin-susceptible Staphylococcus aureus Bacteremia: A Randomized, Controlled TrialCitationClinical Inf...

レビュー:緊急対策か?希望の光か?イギリスの淋菌ワクチン接種プログラムが示す新たな感染症戦略 Journal of Infection

22 Sep 2025

Contributed by Lukas

The United Kingdom meningococcal vaccine (4CMenB) programme against gonorrhoea: a review of the evidence and knowledge gapsCitationJournal of Infectio...

ガイドライン:CDI治療ガイドラインが示す「再発阻止」の新常識と選択肢 CID

21 Sep 2025

Contributed by Lukas

Clinical Practice Guideline by the Infectious Diseases Society of America (IDSA) and Society for Healthcare Epidemiology of America (SHEA): 2021 Focus...

大規模コホートにおける非HIV免疫抑制者におけるPCP肺炎の疫学とアウトカム OFIDや

21 Sep 2025

Contributed by Lukas

An Observational Analysis of a Large Cohort of Pneumocystis jirovecii PneumoniaCitationOFID, ofaf390, https://doi.org/10.1093/ofid/ofaf390論文の要...

ノババックス先行、ファイザーブースター:異種接種がもたらす驚異の免疫応答と安全性_–_COV-BOOSTサブスタディ徹底解説 Journal of Infection

21 Sep 2025

Contributed by Lukas

Heterologous COVID-19 vaccine schedule with protein-based prime (NVX-CoV2373) and mRNA boost (BNT162b2) induces strong humoral responses: results from...

帯状疱疹再発リスクは?シングリックスワクチン接種後の安全性と免疫応答を徹底解説! Journal of Infection

20 Sep 2025

Contributed by Lukas

Herpes zoster recurrence, and safety and immunogenicity of the recombinant zoster vaccine in adults aged ≥50 years with a history of herpes zoster: ...

帯状疱疹ワクチンが心臓と脳卒中リスクを下げるとは?!驚きの新知見と隠された可能性を徹底解剖 Journal of Infection

20 Sep 2025

Contributed by Lukas

Adjuvanted Recombinant Zoster Vaccine Is Effective Against Herpes Zoster Ophthalmicus, and Is Associated with Lower Risk of Acute Myocardial Infarctio...

レビュー:急性脳炎の最新の診断と治療戦略 CID

20 Sep 2025

Contributed by Lukas

State of the Art: Acute EncephalitisCitationClinical Infectious Diseases, ciad306論文の要約本レビューは、成人および小児の急性脳...

20年ぶり!米国でマラリア国内感染、その謎と日本への教訓 MMWR

19 Sep 2025

Contributed by Lukas

Outbreak of Locally Acquired Mosquito-Transmitted (Autochthonous) Malaria — Florida and Texas, May–July 2023CitationMMWR Morbidity and Mortality W...

消えたはずのポリオがNYで再燃?ワクチン由来ウイルスが示すグローバル社会の落とし穴 MMWR

19 Sep 2025

Contributed by Lukas

Public Health Response to a Case of Paralytic Poliomyelitis in an Unvaccinated Person and Detection of Poliovirus in Wastewater — New York, June–A...

レビュー:菌血症の病因機序と介入の可能性 Nature Reviews Microbiology

19 Sep 2025

Contributed by Lukas

Bloodstream infections: mechanisms of pathogenesis and opportunities for interventionCitationNature Reviews Microbiology, vol. 23, pp. 210–224 (...

SFTSが西日本を越え、全国に拡大する:マダニ媒介感染症の全貌と最新対策

19 Sep 2025

Contributed by Lukas

元の文書:国内外における重症熱性血小板減少症候群(SFTS)の発生状況についてCitation:IASR. 2024 Aug 1.この報告は...

見過ごされがちなダニ媒介感染症CRT 知られざる病の実態に迫る. NEJM, Annals of Internal Medicineまとめ

18 Sep 2025

Contributed by Lukas

Human Infection with Candidatus Rickettsia tarasevichiaeCitationNew England Journal of Medicine, 2013; 369(12): 1178–1180概要中国北東部にお...

結核治療に革命か?6ヶ月が8週間に短縮!?「TRUNCATE-TB試験」が示す新たな可能性 NEJM

18 Sep 2025

Contributed by Lukas

Treatment Strategy for Rifampin-Susceptible TuberculosisCitationNew England Journal of Medicine, 2023; 388(10): 873–887論文の要約本試験は、...

レビュー:非結核性抗酸菌による肺疾患:患者、原則、そして展望 CID

18 Sep 2025

Contributed by Lukas

State-of-the-Art Review: Nontuberculous Mycobacterial Pulmonary Disease: Patients, Principles, and ProspectsCitationClinical Infectious Diseases, ciae...

レビュー:トランスジェンダー・ジェンダー多様性(TGD)患者のケアにおけるデータと信頼の構築 CID

17 Sep 2025

Contributed by Lukas

State-of-the-Art Review: Data and Trust to Improve Care for Transgender and Gender-Diverse PatientsCitationClinical Infectious Diseases, 2025; 80(2): ...

レビュー:身近に潜むHAI(医療関連感染症)の衝撃と、私たちにできる7つの予防戦略 Risk Management and Healthcare Policy

17 Sep 2025

Contributed by Lukas

元の論文:Strategies to Prevent Healthcare-Associated Infections: A Narrative OverviewCitation:Risk Manag Healthc Policy. 2020;13:1765–1780論...

日本のダニに潜む謎のウイルス:新種発見から感染の鍵、そして潜在リスクまで Ticks Tick Borne Dis

17 Sep 2025

Contributed by Lukas

A wide distribution of Beiji nairoviruses and related viruses in Ixodes ticks in JapanCitationTicks and Tick-borne Diseases, 15: 102380 (2024)論文の...

未知の侵入者_Beiji nairovirus:ダニと家畜が運ぶ謎のウイルス、鍵なき感染の真相に迫る Emerging Microbes & Infections

17 Sep 2025

Contributed by Lukas

A new nairo-like virus associated with human febrile illness in ChinaCitationEmerging Microbes & Infections, 2021; 10(1): 1200–1208論文の要約...

医療現場の「手指衛生」:20年の進化と未来への課題 Lancet ID

16 Sep 2025

Contributed by Lukas

元の論文:Hand hygiene in health care: 20 years of ongoing advances and perspectivesCitation:Lancet Infect Dis. 2021;21:e209–21論文の要約...

ダニ媒介の新顔「ソンリンウイルス(SGLV)」徹底解説:未知の脅威とその対策 nature medicine

16 Sep 2025

Contributed by Lukas

Identification of a new orthonairovirus associated with human febrile illness in ChinaCitationNature Medicine, 2021; 27(3): 434–439論文の要約本...

新ウイルス「Wetland virus」の脅威:マダニ媒介の未知なる病原体と、私たちの未来への問い NEJM

16 Sep 2025

Contributed by Lukas

A New Orthonairovirus Associated with Human Febrile IllnessCitationNew England Journal of Medicine, 2024; 391(9): 821–831論文の要約中国北東...

カルバペネム耐性菌に挑む新薬「セフィデロコル」を深掘り!CREDIBLE-CR試験から見えた光と影  Lancet ID

16 Sep 2025

Contributed by Lukas

Efficacy and safety of cefiderocol or best available therapy for the treatment of serious infections caused by carbapenem-resistant Gram-negative bact...

レビュー:HIV陽性者に対する肛門がんスクリーニングの最新知見 CID

16 Sep 2025

Contributed by Lukas

State-of-the-Art Review: Anal Cancer Screening in People With HIVCitationClinical Infectious Diseases, 2025; 80(6): e80–e88論文の要約この総説...

日本初のSFTS院内感染事例から学ぶべき教訓:研修医の感染経路と標準予防策の重要性 IJID

15 Sep 2025

Contributed by Lukas

元の論文:First case of nosocomial transmission of severe fever with thrombocytopenia syndrome in JapanCitation:Int J Infect Dis. 2025; in pres...

レビュー:病院の清潔さの深層 HAIを防ぐ実践的清掃・消毒戦略と人の力 Journal of Hospital Infection

15 Sep 2025

Contributed by Lukas

元の論文:Practical recommendations for routine cleaning and disinfection procedures in healthcare institutions: a narrative reviewCitation:J H...

日本のマダニから見つかる新ウイルス:JMTVと新種TAKV、驚きの垂直伝播と潜在リスクを深掘り Viruses

15 Sep 2025

Contributed by Lukas

Detection of Jingmenviruses in Japan with Evidence of Vertical Transmission in TicksCitationViruses, 2021; 13(12): 2547論文の要約日本の複数の...

新マダニ媒介ウイルス「アロンシャン」の脅威:日本にも潜む未確認病原体か? NEJM

15 Sep 2025

Contributed by Lukas

A New Segmented Virus Associated with Human Febrile Illness in ChinaCitationNew England Journal of Medicine, 2019; 380(22): 2116–2125論文の要約...

レビュー:気候変動が変える感染症リスク 蚊・マダニから薬剤耐性まで、米国の現状からワンヘルスを考える CID

15 Sep 2025

Contributed by Lukas

Climate Change and the Epidemiology of Infectious Diseases in the United StatesCitationClinical Infectious Diseases, 2023; 76(5): 950–956論文の要...

レビュー:脊椎インプラント感染症の診断と管理の最前線 CID

14 Sep 2025

Contributed by Lukas

State-of-the-Art Review: Diagnosis and Management of Spinal Implant InfectionsCitationClinical Infectious Diseases, 2024; 79(6): e65–e71論文の要...

ガイドライン:複雑な耐性菌対策 接触予防策の中止基準 MRSA, VRE, MDR-E, CD ICHE

14 Sep 2025

Contributed by Lukas

元の論文:Duration of Contact Precautions for Acute-Care SettingsCitation:Infect Control Hosp Epidemiol. 2018;39(2):127–144論文の要約こ...

性感染症の未来を拓く?】髄膜炎ワクチンが淋菌に効く驚きの可能性を徹底解明! Lancet ID

14 Sep 2025

Contributed by Lukas

Effectiveness of a serogroup B outer membrane vesicle meningococcal vaccine against gonorrhoea: a retrospective observational studyCitationLancet Infe...

HPVワクチン、イギリスで子宮頸がんを87%減少!現実世界データが示す驚異の予防効果と未来への問いかけ Lancet

14 Sep 2025

Contributed by Lukas

The effects of the national HPV vaccination programme in England, UK, on cervical cancer and grade 3 cervical intraepithelial neoplasia incidence: a r...

HIV関連クリプトコッカス髄膜炎治療のブレイクスルー:たった1回の注射で、より安全に命を救う新常識 NEJM

14 Sep 2025

Contributed by Lukas

Single-Dose Liposomal Amphotericin B Treatment for Cryptococcal MeningitisCitationNew England Journal of Medicine, 2022; 386(12): 1109–1120論文の...

レビュー:Staphylococcus aureus菌血症の現代的マネジメントにおける課題と論点 CID

13 Sep 2025

Contributed by Lukas

Contemporary Management of Staphylococcus aureus Bacteremia—Controversies in Clinical PracticeCitationClinical Infectious Diseases, 2023; 77(11): e5...

メトホルミンはCOVID-19の回復を早めるか?大規模臨床試験ACTIV-6の結果と今後の展望 JAMA Internal Medicine

13 Sep 2025

Contributed by Lukas

元の論文:Metformin and Time to Sustained Recovery in Adults With COVID-19: The ACTIV-6 Randomized Clinical TrialCitation:JAMA Intern Med. 2025...

糖尿病薬メトホルミンがCOVID-19後遺症(PCC)リスクを64%低減? CID

13 Sep 2025

Contributed by Lukas

Effect of Metformin on the Risk of Post–coronavirus Disease 2019 Condition Among Individuals With Overweight or Obese: A Population-based Retrospect...

レビュー:生物学的製剤と感染症 ピンポイント治療の落とし穴と予防戦略 Clinical Microbiology and Infection

13 Sep 2025

Contributed by Lukas

ESCMID Study Group for Infections in Compromised Hosts (ESGICH) Consensus Document on the safety of targeted and biological therapies: an infectious d...

ポリオ根絶へ大転換!副作用リスクを克服した次世代ワクチンnOPV2の衝撃成果 Lancet

13 Sep 2025

Contributed by Lukas

Safety and immunogenicity of two novel type 2 oral poliovirus vaccine candidates compared with a monovalent type 2 oral poliovirus vaccine in healthy ...

流行情報:感染症発生動向調査週報(IDWR)国立感染症研究所 2025年第35号

13 Sep 2025

Contributed by Lukas

感染症発生動向調査週報(IDWR)第27巻第35号Citation:厚生労働省・国立感染症研究所, 2025年9月12日発行発生動向の...

レビュー:Long COVIDと自己抗体 Lancet ID

12 Sep 2025

Contributed by Lukas

元の論文:Autoantibodies in long COVID: a systematic reviewCitation:Lancet Infect Dis. 2025;25(9):e476–e489論文の要約このシステマテ...

症例報告:死の淵からの生還、キャンプが招いた謎の呼吸不全の真実に迫る NEJM

12 Sep 2025

Contributed by Lukas

Case 15-2025: A 52-Year-Old Man with Fever, Nausea, and Respiratory FailureCitationN Engl J Med. 2025 May 29;392(20):2049–2057. doi:10.1056/NEJMcpc2...

エボラ出血熱:危機下で命を救った治療薬の真実~コンゴPALM試験の衝撃と未来への課題~ NEJM

12 Sep 2025

Contributed by Lukas

A Randomized, Controlled Trial of Ebola Virus Disease TherapeuticsCitationNew England Journal of Medicine, 2019; 381(24): 2293–2303論文の要約コ...

コンゴ民主共和国エボラ大流行下でのrVSV-ZEBOVワクチン有効性:困難な現場での84%という驚異の成果を徹底究明! Lancet

12 Sep 2025

Contributed by Lukas

Effectiveness of rVSV-ZEBOV Vaccination during the 2018–20 Ebola Virus Disease Epidemic in the Democratic Republic of the Congo: a Retrospective Tes...

レビュー:遷延性Enterococcus菌血症の診断と治療の現状と課題 CID

12 Sep 2025

Contributed by Lukas

State-of-the-Art Review: Persistent Enterococcal BacteremiaCitationClinical Infectious Diseases, 2024; 78(1): e1–e11論文の要約本レビューは...

アメリカ血液培養ボトル不足の真実:診断の質と患者ケアへの知られざる影響 CID

11 Sep 2025

Contributed by Lukas

元の論文:The Impact of a Nationwide Blood Culture Bottle Shortage in 2024 on Healthcare Facilities in the United StatesCitation:Clin Infect Di...

ルワンダ首都を襲ったマールブルグウイルス病:都市型アウトブレイクからの教訓と未来への課題 NEJM

11 Sep 2025

Contributed by Lukas

元の論文:Marburg Virus Disease in Rwanda, 2024 — Public Health and Clinical ResponsesCitation:N Engl J Med. 2025;393:983–993論文の要約...

進行がん終末期ケア:広域抗菌薬の使用パターンと意思決定の転換点 JAMA Network Open

11 Sep 2025

Contributed by Lukas

元の論文:Broad-Spectrum Antibiotic Use at the End of Life in Patients With Advanced CancerCitation:JAMA Netw Open. 2025;8(9):e2530980論文の...

接触予防策、本当に必要?MRSA・VRE対策の常識を覆す大規模研究と、手指衛生の重要性 ICHE

11 Sep 2025

Contributed by Lukas

Discontinuing MRSA and VRE Contact Precautions: Defining Hospital Characteristics and Infection Prevention Practices Predicting Safe De-escalationCita...

レビュー:終末期医療における抗菌薬使用と感染症専門医の役割 CID

11 Sep 2025

Contributed by Lukas

State-of-the-Art Review: Use of Antimicrobials at the End of LifeCitationClinical Infectious Diseases, 2024; 78(3): e27–e36論文の要約このレビ...

レビュー:長期グルココルチコイド療法による日和見感染症のリスク CID

10 Sep 2025

Contributed by Lukas

Unintended Consequences: Risk of Opportunistic Infections Associated With Long-term Glucocorticoid Therapies in AdultsCitationClinical Infectious Dise...

症例報告:迷宮入り症例!75歳男性の複雑性肺感染症 NEJM

10 Sep 2025

Contributed by Lukas

Case 21-2025: A 75-Year-Old Man with Cough, Dyspnea, and HypoxemiaCitationN Engl J Med. 2025 Jul 24;393(4):390–399. doi:10.1056/NEJMcpc2412532概要...

症例報告:空港マラリアの謎を解く チュニジアの奇妙な感染事例から見えてくる、グローバル移動の意外なリスクと公衆衛生の課題 Malaria Jorunal

10 Sep 2025

Contributed by Lukas

Airport malaria: report of four cases in TunisiaCitationMalar J. 2015;14:42. doi:10.1186/s12936-015-0566-x概要本報告は、2013年夏にチュニジ...

B型肝炎「機能的治癒」への光明か?新薬ベピロビルセンの画期性と残された課題 NEJM

10 Sep 2025

Contributed by Lukas

Efficacy and Safety of Bepirovirsen in Chronic Hepatitis B InfectionCitationNew England Journal of Medicine, 2022; 387(21): 1957–1968論文の要約...

HIV治療と予防を変える長時間作用型注射薬カボテグラビル:服薬負担軽減と画期的な効果の可能性 NEJM, Lancetまとめ

10 Sep 2025

Contributed by Lukas

Cabotegravir for HIV Prevention in Cisgender Men and Transgender WomenNew England Journal of Medicine, 2021; 385:595–608Global, regional, and nation...

高齢者のRSV入院を83%削減!デンマークの大規模実世界研究が示すRSVpreFワクチンの真価と隠れたインパクト NEJM

09 Sep 2025

Contributed by Lukas

RSV Prefusion F Vaccine for Prevention of Hospitalization in Older AdultsCitationN Engl J Med. 2025 Aug 30; DOI:10.1056/NEJMoa2509810概要この研究...

レビュー:腸チフスのメアリー 公衆衛生と個人の自由、100年後の私たちへの問い Annals of Gastroenterology

09 Sep 2025

Contributed by Lukas

Mary Mallon (1869–1938) and the history of typhoid feverCitationAnn Gastroenterol. 2013;26(2):132–134.概要本論文は、米国において「チ...

新生児を守るRSVワクチン:妊娠中の接種が乳児の重症化・入院を8割以上抑制する?最新研究と安全性を徹底解説 NEJM

09 Sep 2025

Contributed by Lukas

Bivalent Prefusion F Vaccine in Pregnancy to Prevent RSV Illness in InfantsCitationNew England Journal of Medicine, 2023; 388:1451–1464論文の要約...

高齢者のRSウイルス肺炎に切り札か?待望のワクチン候補RSVPreF3 OAの驚くべき効果と安全性 NEJM

09 Sep 2025

Contributed by Lukas

Respiratory Syncytial Virus Prefusion F Protein Vaccine in Older AdultsCitationNew England Journal of Medicine, 2023; 388:595–608論文の要約AReS...

レビュー:ヒト皮膚マイクロバイオームの構成・機能と治療応用展望 Nature Reviews Microbiology

09 Sep 2025

Contributed by Lukas

The human skin microbiome: from metagenomes to therapeuticsCitationNature Reviews Microbiology, 2025 (オンライン先行)論文の要約本レビュ...

デング熱ワクチンTAK-003、ブラジル大流行で分かった「本当の力」:速攻vs持続、そして見えた課題 Lancet ID

08 Sep 2025

Contributed by Lukas

Effectiveness of the TAK-003 dengue vaccine in adolescents during the 2024 outbreak in São Paulo, Brazil: a test-negative, case–control studyCitati...

デング熱は性感染症?意外な感染経路と公衆衛生の真実 ジカ熱との違いを徹底解明 Journal of Travel Medicine

08 Sep 2025

Contributed by Lukas

Can dengue virus be sexually transmitted?CitationJ Travel Med. 2019;26(3):tay157. doi:10.1093/jtm/tay157概要本論文は、デングウイルス(D...

デング熱新ワクチン「Qdenga」4年半の追跡調査:その真の有効性と安全性、そして残された課題とは?

08 Sep 2025

Contributed by Lukas

Long-term efficacy and safety of a tetravalent dengue vaccine (TAK-003): 4·5-year results from a phase 3, randomised, double-blind, placebo-controlle...

デング熱新ワクチン「TAK-003」徹底解剖:80%以上の有効性と型別課題、過去の感染歴を超えた光明か? NEJM

08 Sep 2025

Contributed by Lukas

Efficacy of a Tetravalent Dengue Vaccine in Healthy Children and AdolescentsCitationNEJM, 2019; 381(21): 2009–2019論文の要約本試験は、デン...

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